Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fabrice, Lestienne"'
Autor:
Marie-Dominique Thouvenin, Adeline Bacquey, Marine Babin, Fabrice Lestienne, Christophe Lauze, Eléonore Gravier, Diana Placintescu, Ariadna Ortiz-Brugués, Sonja Ständer
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 12, Pp 3137-3151 (2023)
Abstract Introduction Pruritus is a prevalent symptom, described as one of the most bothersome of psoriasis. Specific itch management remains a challenge, for which hydrotherapy could be used as adjunct care to medical treatment. Therefore, we assess
Externí odkaz:
https://doaj.org/article/ebf99eba8feb40c09f7fcf45c6ec4578
Autor:
Daniel Redoules, Eléonore Gravier, Stéphanie Bosch, Magali Savignac, Marie Tauber, Fabrice Lestienne, Marie-Dominique Thouvenin, Marion Mars, Christian Rouvière, Simon Lachambre, Carle Paul, Alexia Brocario, Catherine Leclerc, Marine Babin, Marc Moreau, Clara Douzal, Lucette Pelletier, Jean-Charles Guéry, Hélène Duplan, Isabelle Néant
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:1348-1357
Background Type-17 inflammation characterizes psoriasis, a chronic skin disease. Because several inflammatory cytokines contribute to psoriasis pathogenesis, inhibiting the simultaneous production of these cytokines in TH17 cells may be beneficial in
Autor:
Marion, Mars, Isabelle, Néant, Catherine, Leclerc, Stéphanie, Bosch, Christian, Rouviere, Marc, Moreau, Simon, Lachambre, Carle, Paul, Marie, Tauber, Eléonore, Gravier, Clara, Douzal, Hélène, Duplan, Marine, Babin, Alexia, Brocario, Marie-Dominique, Thouvenin, Jean-Charles, Guéry, Daniel, Redoules, Fabrice, Lestienne, Lucette, Pelletier, Magali, Savignac
Publikováno v:
The Journal of allergy and clinical immunology. 149(4)
Type-17 inflammation characterizes psoriasis, a chronic skin disease. Because several inflammatory cytokines contribute to psoriasis pathogenesis, inhibiting the simultaneous production of these cytokines in TWe sought to investigate the role of CaTr
Autor:
Jean-Claude Martel, Cussac Didier, Fabrice Lestienne, Adrian Newman-Tancredi, P. Heusler, Mark A. Varney, Cristina Cosi
Publikováno v:
Journal of Pharmacy and Pharmacology. 69:1178-1190
Objectives NLX-112 (befiradol, F13640) is a selective serotonin 5-HT1A receptor agonist. Although it has been tested in vivo, little has been reported on its in vitro signal transduction profile. Methods NLX-112 was tested on G-protein activation, in
Autor:
Cussac Didier, Adrian Newman-Tancredi, Fabrice Lestienne, Anne-Marie Ormière, Jean-Claude Martel, Mark A. Varney
Publikováno v:
Cellular Signalling. 63:109383
A previous study observed bell-shaped concentration-response isotherms for activation of Gαi3 G-protein subunits by high efficacy 5-HT1A receptor agonists in a Chinese hamster ovary (CHO) cell line expressing high levels of these receptors. This sug
Distinctive in vitro signal transduction profile of NLX-112, a potent and efficacious serotonin 5-HT
Autor:
Adrian, Newman-Tancredi, Jean-Claude, Martel, Cristina, Cosi, Peter, Heusler, Fabrice, Lestienne, Mark A, Varney, Didier, Cussac
Publikováno v:
The Journal of pharmacy and pharmacology. 69(9)
NLX-112 (befiradol, F13640) is a selective serotonin 5-HTNLX-112 was tested on G-protein activation, inhibition of adenylyl cyclase, ERK1/2 phosphorylation (pERK) and receptor internalization in recombinant cell lines. NLX-112 was also tested on G-pr
Autor:
Stéphanie Tardif, Amélie Tourette, David Troulier, Antoine Dumoulin, Marie‐Thérèse Calmettes, Delphine Denais-Lalieve, Marie-Christine Ailhaud, Claudie Cathala, Luc De Vries, Isabelle Rauly-Lestienne, Anne-Dominique Degryse, Emilie Lauressergues, Didier Cussac, Fabrice Lestienne, Peter Heusler
Publikováno v:
Pharmacology Research & Perspectives
The Hedgehog (HH) pathway has been linked to the formation of basal cell carcinoma (BCC), medulloblastoma, and other cancers. The recently approved orally active drugs vismodegib (GDC‐0449) and sonidegib (LDE–225) were not only efficacious for th
Autor:
Joëlle Riond, Didier Cussac, Lucie Fournier, Florence Busato, Jérome Besse, Cécile Desjobert, Jörg Tost, Sophie Bréand, Stéphane Vispé, Emeline Davoine, Natacha Novosad, Fabrice Lestienne, Luc De Vries, Arthur Deroide, Paola B. Arimondo
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2015, 6 (17), pp.15265-15282. ⟨10.18632/oncotarget.3317⟩
Scopus-Elsevier
Oncotarget, 2015, 6 (17), pp.15265-15282. ⟨10.18632/oncotarget.3317⟩
Europe PubMed Central
Oncotarget, Impact journals, 2015, 6 (17), pp.15265-15282. ⟨10.18632/oncotarget.3317⟩
Scopus-Elsevier
Oncotarget, 2015, 6 (17), pp.15265-15282. ⟨10.18632/oncotarget.3317⟩
Europe PubMed Central
// Stephane Vispe 1 , Arthur Deroide 1 , Emeline Davoine 1 , Cecile Desjobert 1 , Fabrice Lestienne 2 , Lucie Fournier 1 , Natacha Novosad 1 , Sophie Breand 3 , Jerome Besse 3 , Florence Busato 4 , Jorg Tost 4 , Luc De Vries 2 , Didier Cussac 2 , Joe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66560f2157e2f74b389fb7912920127c
https://hal-pasteur.archives-ouvertes.fr/pasteur-03043762
https://hal-pasteur.archives-ouvertes.fr/pasteur-03043762
Autor:
Fabrice Lestienne, Yves Rival, Anne Rouquette, Didier Junquero, Aline Stennevin, Thierry Wurch, Jean-Francois Patoiseau, Laurence Puech, Elisabeth Dupont-Passelaigue, Claudie Cathala
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 311:467-475
Peroxisome proliferator-activated receptors (PPARs) regulate storage and catabolism of fats and carbohydrates. PPARgamma activity increases insulin sensitivity and adipocyte differentiation at the expense of adipogenesis and weight gain. The goal of