Výsledky vyhledávání - "Fabrice, Gaston"

Structure-antigenicity of the V3 region of SIVmac envelope glycoprotein

Autor: Faouzi Lakhdar-Ghazal, Elmostafa Bahraoui, Tahar Babas, Fabrice Gaston

Publikováno v: Journal of Peptide Science. 16:48-57

The objective of this study was to analyze the immunogenicity and antigenicity of the V3 domain (Cys313–Cys346) of the external envelope glycoprotein gp125 of SIVmac251. The corresponding peptide was synthesized and characterized as linear and cycl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04d0874c6f6b33a8077173ea3c465b1e
https://doi.org/10.1002/psc.1193

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Development and Characterization of Peptidic Fusion Inhibitors Derived from HIV-1 gp41 with Partial D-Amino Acid Substitutions

Autor: Elmostafa Bahraoui, Fabrice Gaston, Sergio Madurga, Giovana C. Granados, Francesc Rabanal, Faouzi Lakhdar-Ghazal, Ernest Giralt

Publikováno v: ChemMedChem. 4:570-581

The aim of this study was to design synthetic peptides with D-amino acid substitutions that mimic the human immunodeficiency virus (HIV) gp41 HR2 region. The objective was to develop new and active C34 analogue peptides by introducing D-amino acid po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d256d9d2dac1d9192851b0e201d0bd
https://doi.org/10.1002/cmdc.200800390

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Design of HR1 and HR2 synthetic peptide analogs: Characterization of their antiviral activities and their capacities to induce neutralizing antibodies

Autor: Ernest Giralt, Elmostafa Bahraoui, Meritxell Teixidó, Olfa Mzoughi, Giovana C. Granados, Esther Zurita, Ibtissem Hamimmed, Miguel Moreno, Fabrice Gaston

Publikováno v: Retrovirology
Retrovirology, 2013, 10 (Suppl 1), pp.P112
Retrovirology, BioMed Central, 2013, 10 (Suppl 1), pp.P112

Background HIV-1 entry is a dynamic process with two main actors: HIV-1 envelope glycoproteins: gp120 and gp41. The entry is a key step of the infection: blockade of this step leads to an inhibition of the viral replication. Our main focus in this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2762a84dded9a838693e7420cfde86a4
https://www.hal.inserm.fr/inserm-00873099

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Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

Autor: Fabrice Gaston, Xavier Contreras, Elmostafa Bahraoui, Matija B. Peterlin, Olfa Mzoughi

Publikováno v: Retrovirology
Retrovirology, BioMed Central, 2012, 9 (1), pp.37. ⟨10.1186/1742-4690-9-37⟩
Retrovirology, 2012, 9 (1), pp.37. ⟨10.1186/1742-4690-9-37⟩
Contreras, Xavier; Mzoughi, Olfa; Gaston, Fabrice; Peterlin, Matija B; & Bahraoui, Elmostafa. (2012). Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages. Retrovirology, 9(1), 37. doi: http://dx.doi.org/10.1186/1742-4690-9-37. Retrieved from: http://www.escholarship.org/uc/item/0gb9m1ww
Retrovirology, Vol 9, Iss 1, p 37 (2012)

Background Macrophages, which are CD4 and CCR5 positive, can sustain HIV-1 replication for long periods of time. Thus, these cells play critical roles in the transmission, dissemination and persistence of viral infection. Of note, current antiviral t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9ab7b12e9b4dd8a9a0065d5c439c21
https://www.hal.inserm.fr/inserm-00727309/document

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Fusion intermediates of HIV-1 gp41 as targets for antibody production: design, synthesis, and HR1-HR2 complex purification and characterization of generated antibodies

Autor: Elmostafa Bahraoui, Giovana C. Granados, Olfa Mzoughi, Ernest Giralt, Fabrice Gaston, Faouzi Lakhdar-Ghazal

Publikováno v: ChemMedChem. 5(11)

The objective of this project was to study the interaction between HR1 and HR2, the stability of the complex formed, and to characterize the antibodies produced against monomeric HR1 and HR2 peptides as well as the HR1-HR2 complex. In this work, HR1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2800b370fad10fab9540d0e28ad937
https://pubmed.ncbi.nlm.nih.gov/20922745

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Structure-antigenicity of the V3 region of SIVmac envelope glycoprotein

Autor: Fabrice, Gaston, Tahar, Babas, Faouzi, Lakhdar-Ghazal, Elmostafa, Bahraoui

Publikováno v: Journal of peptide science : an official publication of the European Peptide Society. 16(1)

The objective of this study was to analyze the immunogenicity and antigenicity of the V3 domain (Cys313-Cys346) of the external envelope glycoprotein gp125 of SIVmac251. The corresponding peptide was synthesized and characterized as linear and cyclic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ba63a0ef2d4c8694254b7e49e08439e
https://pubmed.ncbi.nlm.nih.gov/19908202

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