Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fabrice, Cerini"'
Autor:
Sabrina Pagano, Hubert Gaertner, Fabrice Cerini, Tiphaine Mannic, Nathalie Satta, Priscila Camillo Teixeira, Paul Cutler, François Mach, Nicolas Vuilleumier, Oliver Hartley
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132780 (2015)
Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis and treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers for use in risk stratifi
Externí odkaz:
https://doaj.org/article/d71fe6cec5384c9a8e8759ee64e05c43
Publikováno v:
AIDS Research and Human Retroviruses, Vol. 33, No 8 (2017) pp. 768-777
In the absence of an effective vaccine, strategies to prevent HIV transmission are urgently needed. Condomless receptive anal intercourse represents a major route of transmission, and efforts are being made to develop strategies, in which potent anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee11b00eb47d49c5f5cb75bea277eb71
https://doi.org/10.1089/aid.2016.0199
https://doi.org/10.1089/aid.2016.0199
Autor:
Alexia Borgeat, Inês De Magalhaes Pinheiro, Kalyana Bharati Akondi, Oliver Hartley, Ilaria Scurci, Marianne Paolini-Bertrand, Fabrice Cerini
Publikováno v:
Biochimica et Biophysica Acta-General Subjects, Vol. 1865, No 1 (2020) P. 129753
Background Chemokine receptor tyrosine sulfation plays a key role in the binding of chemokines. It has been suggested that receptor sulfation is heterogeneous, but no experimental evidence has been provided so far. The potent anti-HIV chemokine analo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f9117585a5e7b84243bc393eea81b0
https://doi.org/10.1016/j.bbagen.2020.129753
https://doi.org/10.1016/j.bbagen.2020.129753
Autor:
Madiha Derouazi, Else-Marit Suso-Inderberg, Hubert François Gaertner, Pierre-Yves Dietrich, Paul R. Walker, Wilma Di Berardino-Besson, Sébastien Wälchli, Oliver Hartley, Elodie Belnoue, Fabrice Cerini, Andres M. Salazar, Stéphane König, Susanna Carboni, Isabelle Dunand-Sauthier
Publikováno v:
Molecular Therapy, Vol. 24, No 9 (2016) pp. 1675-1685
Cell penetrating peptides (CPPs) from the protein ZEBRA are promising candidates to exploit in therapeutic cancer vaccines, since they can transport antigenic cargos into dendritic cells and induce tumor-specific T cells. Employing CPPs for a given c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3568b34984c582fb7ffb039f337387ee
https://doi.org/10.1038/mt.2016.134
https://doi.org/10.1038/mt.2016.134
Publikováno v:
Journal of Biological Chemistry, Vol. 293, No 49 (2018) pp. 19092-19100
Peptides represent a promising source of new medicines, but improved technologies are needed to facilitate discovery and optimization campaigns. In particular, longer peptides with multiple disulfide bridges are challenging to produce, and producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7399eedaaf50d805613fa54491af2f
https://archive-ouverte.unige.ch/unige:115805
https://archive-ouverte.unige.ch/unige:115805
Autor:
Fabrice Cerini, Guy Gorochov, Karim Dorgham, Irène Rossitto-Borlat, Hubert François Gaertner, Oliver Hartley, Astrid Melotti
Publikováno v:
Chemokines
Chemokines, pp.47-72, 2016, ⟨10.1016/bs.mie.2015.09.014⟩
Chemokines, pp.47-72, 2016, ⟨10.1016/bs.mie.2015.09.014⟩
Phage display technology, which allows extremely rare ligands to be selected from libraries of variants according to user-defined selection criteria, has made a huge impact on the life sciences. In this chapter, we describe phage display methods for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc3f665466687fe48812e2ebbdb1b19
https://hal.archives-ouvertes.fr/hal-02480548
https://hal.archives-ouvertes.fr/hal-02480548
Autor:
Karim, Dorgham, Fabrice, Cerini, Hubert, Gaertner, Astrid, Melotti, Irène, Rossitto-Borlat, Guy, Gorochov, Oliver, Hartley
Publikováno v:
Methods in Enzymology, Vol. 570 (2016) pp. 47-72
Phage display technology, which allows extremely rare ligands to be selected from libraries of variants according to user-defined selection criteria, has made a huge impact on the life sciences. In this chapter, we describe phage display methods for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::936771d79f8947edf9514ca36a2cfe29
https://archive-ouverte.unige.ch/unige:88614
https://archive-ouverte.unige.ch/unige:88614
Autor:
Stephan B Abramson, Nico Callewaert, Ilya I. Tolstorukov, Michael M. Meagher, Jay C. Harner, Hubert François Gaertner, Anthony R Sump, Dustin J Peterson, Scott Brown, Robin E. Offord, Bram Laukens, Robert C Sealock, Knut Madden, Fabrice Cerini, Scott K. Johnson, John T Harms, Oliver Hartley, Anna M. Oommen
Publikováno v:
Protein Expression and Purification, Vol. 119 (2016) pp. 1-10
Protein Expression and Purification
PROTEIN EXPRESSION AND PURIFICATION
Protein Expression and Purification
PROTEIN EXPRESSION AND PURIFICATION
In the continued absence of an effective anti-HIV vaccine, approximately 2 million new HIV infections occur every year, with over 95% of these in developing countries. Calls have been made for the development of anti-HIV drugs that can be formulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ed5918e72bcd53b6ac92ea4a6c44e4
https://archive-ouverte.unige.ch/unige:88663
https://archive-ouverte.unige.ch/unige:88663
Autor:
Irene Borlat, Brigitte Dufour, Robin E. Offord, Richard J. Fish, Olivier Lebeau, Fabrice Cerini, Marc Parmentier, Gabriel Kuenzi, Astrid Melotti, Jean-Yves Springael, Hubert François Gaertner, Oliver Hartley
Publikováno v:
Protein Engineering, Design and Selection, Vol. 21, No 2 (2008) pp. 65-72
The HIV coreceptor CCR5 is a validated target for both the prevention and therapy of HIV infection. PSC-RANTES, an N-terminally modified analogue of one of the natural chemokine ligands of CCR5 (RANTES/CCL5), is a potent inhibitor of HIV entry into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ec538d98a636a3ec51182e25b12a19
https://doi.org/10.1093/protein/gzm079
https://doi.org/10.1093/protein/gzm079
Autor:
Jill Wilken, Robin E. Offord, Marc Alizon, Laurent Picard, Donald E. Mosier, Alejandra Ramos, Fabrice Cerini, Darren A. Thompson, Cristina Pastore, Nikolaus Heveker, Astrid Melotti, Brigitte Dufour, Oliver Hartley, Stephen J. Kent, Richard J. Fish, Hubert François Gaertner
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 101, No 47 (2004) pp. 16460-5
We have used total chemical synthesis to perform high-resolution dissection of the pharmacophore of a potent anti-HIV protein, the aminooxypentane oxime of [glyoxylyl 1 ]RANTES(2-68), known as AOP–RANTES, of which we designed and made 37 analogs. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15c6f120f7a45a6ec3c7f0b29c2a845
https://doi.org/10.1073/pnas.0404802101
https://doi.org/10.1073/pnas.0404802101