Zobrazeno 1 - 10
of 159 222
pro vyhledávání: '"Fabrice"'
Autor:
Damien Vasseur, Ludovic Bigot, Kristi Beshiri, Juan Flórez-Arango, Francesco Facchinetti, Antoine Hollebecque, Lambros Tselikas, Mihaela Aldea, Felix Blanc-Durand, Anas Gazzah, David Planchard, Ludovic Lacroix, Noémie Pata-Merci, Catline Nobre, Alice Da Silva, Claudio Nicotra, Maud Ngo-Camus, Floriane Braye, Sergey I. Nikolaev, Stefan Michiels, Gérôme Jules-Clement, Ken André Olaussen, Fabrice André, Jean-Yves Scoazec, Fabrice Barlesi, Santiago Ponce, Jean-Charles Soria, Benjamin Besse, Yohann Loriot, Luc Friboulet
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Understanding the resistance mechanisms of tumor is crucial for advancing cancer therapies. The prospective MATCH-R trial (NCT02517892), led by Gustave Roussy, aimed to characterize resistance mechanisms to cancer treatments throu
Externí odkaz:
https://doaj.org/article/e6a5668f34d34175ab097af1e5bb22e4
Autor:
Fabrice Bonnet, Adama Doumbia, Vanessa Machault, Frederic Nogbou Ello, Pantxika Bellecave, Corine Bernice Akpovo, Baba Toumany Sidibe, Laura Fernandez, Antoine Kouamé, Edgard Adjogoua, Mireille Dosso, Serge Niangoran, Valérie Journot, Serge Paul Eholié
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Observational studies suggest a reduction in fatal or severe COVID-19 disease with the use of ACE2 inhibitors and statins. We implemented a randomized controlled tree-arm open label trial evaluating the benefits of adding telmisartan (TLM) o
Externí odkaz:
https://doaj.org/article/6849647e41974c5c839b0d3421ac4bf5
Autor:
Armando Santoro, Garrido Pilar, Daniel S.W. Tan, Jon Zugazagoitia, Frances A. Shepherd, Alessandra Bearz, Fabrice Barlesi, Tae Min Kim, Tobias R. Overbeck, Enriqueta Felip, Can Cai, Eddy Simantini, Tracey McCulloch, Eric S. Schaefer
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Despite promising outcomes of treatment with anti-programmed cell death (PD)-1/PD-ligand (L)1 agents in combination with platinum-doublet chemotherapy (PDC) in the first-line setting, a significant unmet medical need remains in pa
Externí odkaz:
https://doaj.org/article/49d4a4474e494f5081ff231d7fc7b4f8
Autor:
Otávio Henrique Bezerra Pinto, Rafael da Silva Oliveira, Brendo Ramos Ferreira, Julianna Peixoto, Maria Regina Silveira Sartori, Betania Ferraz Quirino, Fabrice Brunet, Ricardo Henrique Kruger
Publikováno v:
Environmental Microbiome, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Dihydrogen (H₂) natural gas is a clean and renewable energy source of significant interest in the transition to sustainable energy. Unlike conventional petroleum-based fuels, H₂ releases only water vapor upon combustion, makin
Externí odkaz:
https://doaj.org/article/a8f9e990691d4aff85ff0fd98573ff33
Autor:
Fabrice E. Graf, Richard N. Goodman, Sarah Gallichan, Sally Forrest, Esther Picton-Barlow, Alice J. Fraser, Minh-Duy Phan, Madalitso Mphasa, Alasdair T. M. Hubbard, Patrick Musicha, Mark A. Schembri, Adam P. Roberts, Thomas Edwards, Joseph M. Lewis, Nicholas A. Feasey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Infections with Enterobacterales (E) are increasingly difficult to treat due to antimicrobial resistance. After ceftriaxone replaced chloramphenicol (CHL) as empiric therapy for suspected sepsis in Malawi in 2004, extended-spectrum beta-lact
Externí odkaz:
https://doaj.org/article/a653d1fed48c4d248ed8875692a5b104
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
Autor:
Samuel Abassah-Oppong, Matteo Zoia, Brandon J. Mannion, Raquel Rouco, Virginie Tissières, Cailyn H. Spurrell, Virginia Roland, Fabrice Darbellay, Anja Itum, Julie Gamart, Tabitha A. Festa-Daroux, Carly S. Sullivan, Michael Kosicki, Eddie Rodríguez-Carballo, Yoko Fukuda-Yuzawa, Riana D. Hunter, Catherine S. Novak, Ingrid Plajzer-Frick, Stella Tran, Jennifer A. Akiyama, Diane E. Dickel, Javier Lopez-Rios, Iros Barozzi, Guillaume Andrey, Axel Visel, Len A. Pennacchio, John Cobb, Marco Osterwalder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Approximately a quarter of the human genome consists of gene deserts, large regions devoid of genes often located adjacent to developmental genes and thought to contribute to their regulation. However, defining the regulatory functions embed
Externí odkaz:
https://doaj.org/article/ea97ba56f1764b518e534e1063bf2e68
Autor:
Youssoufa Maiga, Leon Samuel Moskatel, Seybou H. Diallo, Oumar Sangho, Housseini Dolo, Fatoumata Konipo, Salimata Diallo, Awa Coulibaly, Mariam Daou, Modibo Sangaré, Thomas Coulibaly, Adama Sissoko, Guida Landouré, Mohamed Albakaye, Zoumana Traoré, Abdoul Karim Dao, Mamadou Togo, Saliou Mahamadou, Souleymane dit papa Coulibaly, Najib Kissani, Karamoko Nimaga, Rokia Sanogo, Fabrice Berna, Madani Ouologem, Callixte Kuaté, Robert Cowan, Julien Nizard
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Introduction Neurological disorders (ND) have a high incidence in sub-Saharan Africa (SSA). In this region, systemic challenges of conventional medicine (CM) and cultural beliefs have contributed to a large utilization of traditional medicin
Externí odkaz:
https://doaj.org/article/1ec8c46b5e7745d8b803bf21c43b7457
Autor:
Julie Tottey, Lucie Etienne-Mesmin, Sandrine Chalançon, Alix Sausset, Sylvain Denis, Carine Mazal, Christelle Blavignac, Guillaume Sallé, Fabrice Laurent, Stéphanie Blanquet-Diot, Sonia Lacroix-Lamandé
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Human cryptosporidiosis is distributed worldwide, and it is recognised as a leading cause of acute diarrhoea and death in infants in low- and middle-income countries. Besides immune status, the higher incidence and severity of thi
Externí odkaz:
https://doaj.org/article/296bc824a16244a8a67b49bd5713baf7
Autor:
Yohann Loriot, Maud Kamal, Laurene Syx, Remy Nicolle, Celia Dupain, Naoual Mensourri, Igor Duquesne, Pernelle Lavaud, Claudio Nicotra, Maud Ngocamus, Ludovic Lacroix, Lambros Tselikas, Gilles Crehange, Luc Friboulet, Zahra Castel-Ajgal, Yann Neuzillet, Edith Borcoman, Philippe Beuzeboc, Grégoire Marret, Tom Gutman, Jennifer Wong, Francois Radvanyi, Sylvain Dureau, Jean-Yves Scoazec, Nicolas Servant, Yves Allory, Benjamin Besse, Fabrice Andre, Christophe Le tourneau, Christophe Massard, Ivan Bieche
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Metastatic urothelial carcinoma (mUC) is a lethal cancer, with limited therapeutic options. Large-scale studies in early settings provided critical insights into the genomic and transcriptomic characteristics of non-metastatic UC. The genomi
Externí odkaz:
https://doaj.org/article/e0e414a0867f424a9bfcb03a773faebb
Autor:
Emilie Pacheco Da Silva, Raphaëlle Varraso, Laurent Orsi, Emmanuel Wiernik, Marcel Goldberg, Christophe Paris, Léopold K. Fezeu, Céline Ribet, Rachel Nadif, Fabrice Carrat, SAPRIS study group, Mathilde Touvier, Marie Zins, Orianne Dumas, Nicole Le Moual
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Few studies evaluated the use of Household Disinfectant and Cleaning Products (HDCPs) during the COVID-19 pandemic, but no population-based cohorts used longitudinal data. We studied changes in HDCPs during the first lockdown, bas
Externí odkaz:
https://doaj.org/article/2c2e966f4d0e47ba8fa586136b843c4e