Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation.

Autor: Harlaar N; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, the Netherlands., Dekker SO; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Zhang J; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Snabel RR; Department of Molecular Developmental Biology, Radboud University, Nijmegen, the Netherlands., Veldkamp MW; Department of Clinical and Experimental Cardiology, Amsterdam UMC, Amsterdam, the Netherlands., Verkerk AO; Department of Clinical and Experimental Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.; Department of Medical Biology, Amsterdam UMC, Amsterdam, the Netherlands., Fabres CC; Applied Stem Cell Technologies, University of Twente, Enschede, the Netherlands., Schwach V; Applied Stem Cell Technologies, University of Twente, Enschede, the Netherlands., Lerink LJS; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Rivaud MR; Department of Clinical and Experimental Cardiology, Amsterdam UMC, Amsterdam, the Netherlands., Mulder AA; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands., Corver WE; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Goumans MJTH; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands., Dobrev D; Institute of Pharmacology, University Duisburg-Essen, Essen, Germany., Klautz RJM; Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, the Netherlands., Schalij MJ; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Veenstra GJC; Department of Molecular Developmental Biology, Radboud University, Nijmegen, the Netherlands., Passier R; Applied Stem Cell Technologies, University of Twente, Enschede, the Netherlands., van Brakel TJ; Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, the Netherlands., Pijnappels DA; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., de Vries AAF; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. a.a.f.de_vries@lumc.nl.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2022 Apr; Vol. 6 (4), pp. 389-402. Date of Electronic Publication: 2022 Jan 06.