Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fabiola Porta"'
Publikováno v:
CHIMIA, Vol 75, Iss 9, Pp 766-771 (2021)
The formulation of active ingredients into emulsion- and suspension-based delivery systems offers a wide range of opportunities to produce stable and highly bioavailable product forms for their later application in human and animal nutrition. Recent
Externí odkaz:
https://doaj.org/article/3bd0c54e9126432281b33000888c0b6a
Autor:
Daniel Ehrsam, Fabiola Porta, Janine Hussner, Isabell Seibert, Henriette E Meyer zu Schwabedissen
Publikováno v:
Materials, Vol 12, Iss 17, p 2836 (2019)
Background: It was our intention to develop cathepsin B-sensitive nanoparticles for tumor-site-directed release. These nanoparticles should be able to release their payload as close to the tumor site with a decrease of off-target effects in mind. Cat
Externí odkaz:
https://doaj.org/article/89d8b1f3c1564bb68551db869533dbec
Autor:
Matthias Hamburger, Mouhssin Oufir, Daniel Ehrsam, Jörg Huwyler, Henriette E. Meyer zu Schwabedissen, Fabiola Porta, Sandro Sieber
Publikováno v:
Bioconjugate Chemistry. 31:781-793
The concept of triggered drug release offers a possibility to overcome the toxic side effects of chemotherapeutics in cancer treatment by reducing systemic exposure to the active drug. In the present work, the concept foresees the use of the extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e09be9fa98d559e9690f1e88a6b6976
https://doi.org/10.1021/acs.bioconjchem.9b00865
https://doi.org/10.1021/acs.bioconjchem.9b00865
Autor:
Alexandra Ernst, Jörg Huwyler, Susanne H. Schenk, Philip Grossen, Fabiola Porta, Dominik Witzigmann, Klara Kiene
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 119:322-332
Nanoparticles, such as polymersomes, can be directed to the hepatic asialoglycoprotein receptor to achieve targeted drug delivery. In this study, we prepared asialofetuin conjugated polymersomes based on the amphiphilic di-block copolymer poly(dimeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f71b496d67b0c08e5732332715ca9a4
https://doi.org/10.1016/j.ejpb.2017.07.002
https://doi.org/10.1016/j.ejpb.2017.07.002
Autor:
Janine Hussner, Isabell Seibert, Henriette E. Meyer zu Schwabedissen, Fabiola Porta, Daniel Ehrsam
Publikováno v:
Materials
Materials, Vol 12, Iss 17, p 2836 (2019)
Volume 12
Issue 17
Materials, Vol 12, Iss 17, p 2836 (2019)
Volume 12
Issue 17
Background: It was our intention to develop cathepsin B-sensitive nanoparticles for tumor-site-directed release. These nanoparticles should be able to release their payload as close to the tumor site with a decrease of off-target effects in mind. Cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26b3a74b3559cf94d5e28b9ef92c5c7
https://pubmed.ncbi.nlm.nih.gov/31484396
https://pubmed.ncbi.nlm.nih.gov/31484396
Autor:
Livia Basile, M. Mori, Stefania Villa, Fabiola Porta, Daniel Ehrsam, Lisa Dalla Via, Arianna Gelain, Henriette E. Meyer zu Schwabedissen, Aída Nelly García-Argáez, Fiorella Meneghetti
Aim To develop several new derivatives aimed to complete the studies concerning the antiproliferative profile of the oxadiazole derivative MD77. Materials and methods The substitution pattern around the phenyl rings of this compound was analyzed thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6e5177459568317a52b44b9199c1e8
http://hdl.handle.net/11577/3307474
http://hdl.handle.net/11577/3307474
Publikováno v:
RSC Advances. 6:97636-97640
The asialoglycoprotein receptor (ASGPR) expressed on parenchymal liver cells specifically binds multivalent carbohydrates from desialylated glycoproteins. This feature offers a huge potential for hepatocyte specific drug targeting. In this study, mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095f87b51b95533ec59fcf1db727955f
https://doi.org/10.1039/c6ra18297f
https://doi.org/10.1039/c6ra18297f
Autor:
Ksenia Morozova, Andrea Bulbarello, Matteo Scampicchio, Christian Schaefer, Fabiola Porta, Elger Funda
Publikováno v:
LWT. 117:108594
Oxidative stability is critical in guaranteeing the declared shelf life of new formulations and contributes significantly to time-to-market efficiencies. In this study an innovative method based on isothermal calorimetry is proposed for monitoring th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d27dbc28b5b0980ccb3ba3feb65c3d
https://doi.org/10.1016/j.lwt.2019.108594
https://doi.org/10.1016/j.lwt.2019.108594
Publikováno v:
Molecular pharmaceutics. 15(11)
Cytotoxic compounds used to treat cancer are often associated with adverse events. The development of formulations activated by tumor-specific triggers would allow a reduction of systemic exposure while maintaining therapeutic concentrations in the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a73cfbef435d3b782e04ecb0dee576
https://pubmed.ncbi.nlm.nih.gov/30274515
https://pubmed.ncbi.nlm.nih.gov/30274515
Autor:
Andrej Bieri, Fabiola Porta, Dominik Witzigmann, Sandro Sieber, Cristina Prescianotto-Baschong, Natalja Strelnikova, Thomas Pfohl, Philip Grossen, Jörg Huwyler
Publikováno v:
RSC Advances. 5:74320-74328
Nanocarriers encapsulating gold nanoparticles (AuNPs) hold tremendous promise for numerous biomedical applications. So far only a few fabrication strategies have been investigated and efficient processes for the manufacturing of gold nanohybrids (AuN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bc3bf50583b8406bda9bce92b0853b
https://doi.org/10.1039/c5ra13967h
https://doi.org/10.1039/c5ra13967h