Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Fabiola Cecchi"'
Autor:
Ansh Kapil, Andreas Spitzmüller, Nicolas Brieu, Susanne Haneder, Anatoliy Shumilov, Armin Meier, Fabiola Cecchi, Alice Barkell, Nathalie Harder, Katrin Mittermaier, Ana Hidalgo-Sastre, Regina Alleze, Markus Schick, Günter Schmidt, Hadassah Sade, Zenta Tsuchihashi, Fumitaka Suto, Mark Gustavson, J. Carl Barrett, Danielle Carroll
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Many targeted cancer therapies rely on biomarkers assessed by scoring of immunohistochemically (IHC)-stained tissue, which is subjective, semiquantitative, and does not account for expression heterogeneity. We describe an image analysis-base
Externí odkaz:
https://doaj.org/article/b0bb13ca3be44be6a20f420d905211e6
Autor:
Steve Sweet, David Chain, Wen Yu, Philip Martin, Marlon Rebelatto, Andrew Chambers, Fabiola Cecchi, Yeoun Jin Kim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Mass spectrometry-based targeted proteomics allows objective protein quantitation of clinical biomarkers from a single section of formalin-fixed, paraffin-embedded (FFPE) tumor tissue biopsies. We combined high-field asymmetric waveform ion
Externí odkaz:
https://doaj.org/article/ee7281eae9b34786b420309d30eac8ac
Autor:
Francesca Bergamo, Silvia Dalla Santa, Fotios Loupakis, Krisida Cerma, Anna Tosi, Caterina De Grandis, Anna Dalla Pietà, Enrico Gringeri, Valentina Angerilli, Gaetano Ramondo, Alessandro Rago, Fabiola Cecchi, Stephen Benz, Umberto Cillo, Angelo Paolo Dei Tos, Vittorina Zagonel, Matteo Fassan, Antonio Rosato, Sara Lonardi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The current level of evidence for immunotherapy in previously untreated microsatellite unstable metastatic colorectal cancer is based on recent pieces of evidence of few studies that demonstrated durable response and clinical benefit, in terms of obj
Externí odkaz:
https://doaj.org/article/62fa4157fd0c491396c7545d5fb57ed7
Autor:
Manish A Shah, Zev A Wainberg, Daniel V T Catenacci, Howard S Hochster, James Ford, Pamela Kunz, Fa-Chyi Lee, Howard Kallender, Fabiola Cecchi, Daniel C Rabe, Harold Keer, Anne-Marie Martin, Yuan Liu, Robert Gagnon, Peter Bonate, Li Liu, Tona Gilmer, Donald P Bottaro
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0276211 (2022)
[This corrects the article DOI: 10.1371/journal.pone.0054014.].
Externí odkaz:
https://doaj.org/article/59c2c84b825f40d781e74d4c8add9f83
Autor:
Fabiola Cecchi, Karen Rex, Joanna Schmidt, Cathy D. Vocke, Young H. Lee, Sandra Burkett, Daniel Baker, Michael A. Damore, Angela Coxon, Teresa L. Burgess, Donald P. Bottaro
Publikováno v:
Cancers, Vol 15, Iss 2, p 460 (2023)
Drug resistance is a long-standing impediment to effective systemic cancer therapy and acquired drug resistance is a growing problem for molecularly-targeted therapeutics that otherwise have shown unprecedented successes in disease control. The hepat
Externí odkaz:
https://doaj.org/article/a80b981e67e645ef924150313ab3db86
Autor:
Manish A Shah, Zev A Wainberg, Daniel V T Catenacci, Howard S Hochster, James Ford, Pamela Kunz, Fa-Chyi Lee, Howard Kallender, Fabiola Cecchi, Daniel C Rabe, Harold Keer, Anne-Marie Martin, Yuan Liu, Robert Gagnon, Peter Bonate, Li Liu, Tona Gilmer, Donald P Bottaro
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261994 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0054014.].
Externí odkaz:
https://doaj.org/article/3a8c73388258421cbed41f983d337c90
Autor:
Maud Toulmonde, Carlo Lucchesi, Stéphanie Verbeke, Amandine Crombe, Julien Adam, Damien Geneste, Vanessa Chaire, Audrey Laroche-Clary, Raul Perret, François Bertucci, Frederic Bertolo, Laurence Bianchini, Bérengère Dadone-Montaudie, Todd Hembrough, Steve Sweet, Yeoun Jin Kim, Fabiola Cecchi, François Le Loarer, Antoine Italiano
Publikováno v:
EBioMedicine, Vol 62, Iss , Pp 103131- (2020)
Background: Undifferentiated pleomorphic sarcoma (UPS) is the most frequent, aggressive and less-characterized sarcoma subtype. This study aims to assess UPS molecular characteristics and identify specific therapeutic targets. Methods: High-throughpu
Externí odkaz:
https://doaj.org/article/0185fa0580fe4a78a9027ab7a57a448a
Autor:
Fabiola Cecchi, Todd Hembrough
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Natural killer (NK) cells are immune cells capable of killing virally infected cells and tumor cells without the need for antigen stimulation. Tumors, however, can create a suppressive microenvironment that decreases NK function. A feature
Externí odkaz:
https://doaj.org/article/48d3bd4220aa4c7d9b1edcc8b511b00f
Autor:
Deborah R Kaye, Peter A Pinto, Fabiola Cecchi, Joseph Reilly, Alice Semerjian, Daniel C Rabe, Gopal Gupta, Peter L Choyke, Donald P Bottaro
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157130 (2016)
OBJECTIVE:To measure Met protein content in prostate biopsies guided by fused magnetic resonance and ultrasound imaging, and to measure soluble Met (sMet) protein concentration in plasma samples from patients presenting evidence of prostate cancer. P
Externí odkaz:
https://doaj.org/article/4e639ba113d6431dbbeb804a17b23f21
Autor:
Elaine M. Jagoda, Sibaprasad Bhattacharyya, Joseph Kalen, Lisa Riffle, Avrum Leeder, Stephanie Histed, Mark Williams, Karen J. Wong, Biying Xu, Lawrence P. Szajek, Osama Elbuluk, Fabiola Cecchi, Kristen Raffensperger, Meghana Golla, Donald P. Bottaro, Peter Choyke
Publikováno v:
Molecular Imaging, Vol 14 (2015)
Developing an imaging agent targeting the hepatocyte growth factor receptor protein (Met) status of cancerous lesions would aid in the diagnosis and monitoring of Met-targeted tyrosine kinase inhibitors (TKIS). A peptide targeting Met labeled with [
Externí odkaz:
https://doaj.org/article/b4b698de7cb6463c8bfdf88a43f902f0