Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fabio Wolf"'
Autor:
Eva-Lotta von Rüden, Fabio Gualtieri, Katharina Schönhoff, Maria Reiber, Fabio Wolf, Wolfgang Baumgärtner, Florian Hansmann, Andrea Tipold, Heidrun Potschka
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-14 (2020)
Abstract Background Cumulating evidence from rodent models points to a pathophysiological role of inflammatory signaling in the epileptic brain with Toll-like receptor-4 signaling acting as one key factor. However, there is an apparent lack of inform
Externí odkaz:
https://doaj.org/article/1b13645435504471a5438fa249104a85
Autor:
Marta Nowakowska, Michael Oglesbee, Fabio Wolf, Michael Keck, Eva-Lotta von Rüden, Fabio Gualtieri, Heidrun Potschka
Publikováno v:
Neuroscience. 386:108-120
Strong evidence exists that Toll-like receptor (TLR)-mediated effects on microglia functional states can promote ictogenesis and epileptogenesis. So far, research has focused on the role of high-mobility group box protein 1 as an activator of TLRs. H
Autor:
Steven R. Talbot, Leonie Zieglowski, Dietmar Zechner, Kerstin Schwabe, Simeon O. A. Helgers, Brigitte Vollmar, Tjark Wölk, Christine Häger, Nora Weegh, Andreas Wree, Franz-Tassilo Müller-Graff, Nina Miljanovic, Roelof Maarten van Dijk, Ines Koska, André Bleich, Fabio Wolf, Heidrun Potschka, Angela Kuhla, Lisa Ernst, Babette Koegel, Rene Tolba, Svenja Biernot
Publikováno v:
Laboratory animals. 54(1)
In many animal experiments scientists and local authorities define a body-weight reduction of 20% or more as severe suffering and thereby as a potential parameter for humane endpoint decisions. In this study, we evaluated distinct animal experiments
Autor:
Vera Russmann, Peter Gass, Rupert Palme, Fabio Wolf, R. Maarten van Dijk, Christina Möller, Rainer Hellweg, C. Otzdorff, Heidrun Potschka, Michael Keck, Valentina Di Liberto
Publikováno v:
Epilepsia. 59:765-777
Objective: Rodent epilepsy models can significantly contribute to our understanding of pathophysiological mechanisms and to validation of biomarker and target candidates. Evidence-based severity assessment is a presupposition for the ethical evaluati
Autor:
Heidrun Potschka, Fabio Wolf, Clayton R. Hunt, Fabio Gualtieri, Michael Keck, Eva-Lotta von Rüden, Tej K. Pandita
Publikováno v:
ACS chemical neuroscience. 10(3)
Inflammatory responses involving Toll-like receptor signaling represent a key factor contributing to epileptogenesis. Thus, it is of particular interest to explore the relevance of toll-like receptor ligands and modulators, such as heat shock protein
Autor:
Fabio Wolf, Michael Keck, Vera Bierling, Roelof Maarten van Dijk, Heidrun Potschka, Katharina Schönhoff, Christina Möller
Publikováno v:
Epilepsybehavior : EB. 92
Although an impact of epilepsy on circadian rhythmicity is well-recognized, there are profound gaps in our understanding of the influence of seizures on diurnal rhythms. The effect on activity levels and heart rate is of particular interest as it mig