Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Fabio Vanoli"'
Autor:
Henry de Traux de Wardin, Josephine K. Dermawan, Marie-Sophie Merlin, Leonard H. Wexler, Daniel Orbach, Fabio Vanoli, Gudrun Schleiermacher, Birgit Geoerger, Stelly Ballet, Delphine Guillemot, Eléonore Frouin, Stacy Cyrille, Olivier Delattre, Gaelle Pierron, Cristina R. Antonescu
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract The genomic spectrum of rhabdomyosarcoma (RMS) progression from primary to relapse is not fully understood. In this pilot study, we explore the sensitivity of various targeted and whole-genome NGS platforms in order to assess the best genomi
Externí odkaz:
https://doaj.org/article/6f1928873e1d41818ff5568e4b5f0d3e
Autor:
Fabio Vanoli, Laurie Herviou, Yusuke Tsuda, Patricia Sung, Ziyu Xie, Eve Fishinevich, Soe S. Min, William Mallen, Henry de Traux de Wardin, Yanming Zhang, Maria Jasin, Cristina R. Antonescu
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-9 (2023)
Abstract The discovery of neurotrophic tyrosine receptor kinase (NTRK) gene fusions as pan-tumor oncogenic drivers has led to new personalized therapies in oncology. Recent studies investigating NTRK fusions among mesenchymal neoplasms have identifie
Externí odkaz:
https://doaj.org/article/6d475775db3a45d7a90a1301210e36c8
Autor:
Rohit Prakash, Thomas Sandoval, Florian Morati, Jennifer A. Zagelbaum, Pei-Xin Lim, Travis White, Brett Taylor, Raymond Wang, Emilie C. B. Desclos, Meghan R. Sullivan, Hayley L. Rein, Kara A. Bernstein, Przemek M. Krawczyk, Jean Gautier, Mauro Modesti, Fabio Vanoli, Maria Jasin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Human SWS1, SWSAP1, and SPIDR interact with RAD51, a critical protein for homology-directed repair. Here the authors reveal roles for the mouse SWS1–SWSAP1–SPIDR complex in inter-homolog recombination, including during meiosis, and sister chromat
Externí odkaz:
https://doaj.org/article/1b96dd6800dc4b43afc200198f18973b
Autor:
Federico González, Daniela Georgieva, Fabio Vanoli, Zhong-Dong Shi, Matthias Stadtfeld, Thomas Ludwig, Maria Jasin, Danwei Huangfu
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 651-660 (2013)
Induced pluripotent stem cells (iPSCs) hold great promise for personalized regenerative medicine. However, recent studies show that iPSC lines carry genetic abnormalities, suggesting that reprogramming may be mutagenic. Here, we show that the ectopic
Externí odkaz:
https://doaj.org/article/42225dc0d06f426aa70d80c381455699
Publikováno v:
PLoS Genetics, Vol 6, Iss 11, p e1001205 (2010)
Damage tolerance mechanisms mediating damage-bypass and gap-filling are crucial for genome integrity. A major damage tolerance pathway involves recombination and is referred to as template switch. Template switch intermediates were visualized by 2D g
Externí odkaz:
https://doaj.org/article/641967dd5086490c852f392f3782c8d2
Autor:
Josephine K. Dermawan, Fabio Vanoli, Laurie Herviou, Yun-Shao Sung, Lei Zhang, Samuel Singer, William D. Tap, Ryma Benayed, Tejus A. Bale, Jamal K. Benhamida, Brendan C. Dickson, Cristina R. Antonescu
Publikováno v:
Modern Pathology. 35:1055-1065
To elucidate the mechanisms underlying the divergent clinicopathologic spectrum of EWSR1/FUS::CREB translocation-associated tumors, we performed a comprehensive genomic analysis of fusion transcript variants, recurrent genetic alterations (mutations,
Autor:
Andrew N.J. Tutt, Anita Grigoriadis, Melinda L. Telli, James M. Ford, Shaveta Vinayak, Alan Ashworth, Christopher J. Lord, Jessica Frankum, Hasan Mirza, Maggie C.U. Cheang, Anders Isaksson, Markus Mayrhofer, Maria Jasin, Fabio Vanoli, Sarah Pinder, Cheryl Gillett, Bhavna Sidhu, Shalaka Joshi, Patrycja Gazinska, Vandna Shah, Daniel Weekes, Johnathan Watkins
Supplementary Figure S1. Frequency of genomic aberrations in the KCL TNBC cohort. Supplementary Figure S2. Conceptual diagrams of Scores of Chromosomal Instability Scarring (SCINS). Supplementary Figure S3. Extent and location of SCINS in TNBC. Suppl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094e1985f5e799065b529af5433df180
https://doi.org/10.1158/2159-8290.22531226.v1
https://doi.org/10.1158/2159-8290.22531226.v1
Autor:
Andrew N.J. Tutt, Anita Grigoriadis, Melinda L. Telli, James M. Ford, Shaveta Vinayak, Alan Ashworth, Christopher J. Lord, Jessica Frankum, Hasan Mirza, Maggie C.U. Cheang, Anders Isaksson, Markus Mayrhofer, Maria Jasin, Fabio Vanoli, Sarah Pinder, Cheryl Gillett, Bhavna Sidhu, Shalaka Joshi, Patrycja Gazinska, Vandna Shah, Daniel Weekes, Johnathan Watkins
Supplementary Methods, Figure Legends, Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f34678b3a6f52c27a52aa3119cc173
https://doi.org/10.1158/2159-8290.22531220
https://doi.org/10.1158/2159-8290.22531220
Autor:
Andrew N.J. Tutt, Anita Grigoriadis, Melinda L. Telli, James M. Ford, Shaveta Vinayak, Alan Ashworth, Christopher J. Lord, Jessica Frankum, Hasan Mirza, Maggie C.U. Cheang, Anders Isaksson, Markus Mayrhofer, Maria Jasin, Fabio Vanoli, Sarah Pinder, Cheryl Gillett, Bhavna Sidhu, Shalaka Joshi, Patrycja Gazinska, Vandna Shah, Daniel Weekes, Johnathan Watkins
Supplementary Table S1. KCL TNBC and breast cell line cohort characteristics. Supplementary Table S2. Categories of genomic segment used as the basis for measuring SCINS. Supplementary Table S3. Genes expressed in a SAM of different SCINS clusters. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af647901e150db501520ef97984d3d5
https://doi.org/10.1158/2159-8290.22531217.v1
https://doi.org/10.1158/2159-8290.22531217.v1
Autor:
Andrew N.J. Tutt, Anita Grigoriadis, Melinda L. Telli, James M. Ford, Shaveta Vinayak, Alan Ashworth, Christopher J. Lord, Jessica Frankum, Hasan Mirza, Maggie C.U. Cheang, Anders Isaksson, Markus Mayrhofer, Maria Jasin, Fabio Vanoli, Sarah Pinder, Cheryl Gillett, Bhavna Sidhu, Shalaka Joshi, Patrycja Gazinska, Vandna Shah, Daniel Weekes, Johnathan Watkins
SWEAVE document. R code for SCINS analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c56521fa34f9659ba0fc42cd02277f
https://doi.org/10.1158/2159-8290.22531223.v1
https://doi.org/10.1158/2159-8290.22531223.v1