Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Fabio Sterpone"'
Autor:
Olivier Languin-Cattoën, Emeline Laborie, Daria O. Yurkova, Simone Melchionna, Philippe Derreumaux, Aleksey V. Belyaev, Fabio Sterpone
Publikováno v:
Polymers, Vol 13, Iss 22, p 3912 (2021)
Von Willebrand Factor (vWf) is a giant multimeric extracellular blood plasma involved in hemostasis. In this work we present multi-scale simulations of its three-domains fragment A1A2A3. These three domains are essential for the functional regulation
Externí odkaz:
https://doaj.org/article/b7568d091e654db79d0a0b88bae949b3
Autor:
Stepan Timr, Fabio Sterpone
Publikováno v:
Biology, Vol 10, Iss 12, p 1240 (2021)
In this work, we investigate the β-barrel of superoxide dismutase 1 (SOD1) in a mutated form, the isoleucine 35 to alanine (I35A) mutant, commonly used as a model system to decipher the role of the full-length apoSOD1 protein in amyotrophic lateral
Externí odkaz:
https://doaj.org/article/d0f6d92be7834fde9b7e6a5ae77451f6
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113895 (2014)
In this work we investigate by computational means the behavior of two orthologous bacterial proteins, a mesophilic and a thermophilic tetrameric malate dehydrogenase (MalDH), at different temperatures. Namely, we quantify how protein mechanical rigi
Externí odkaz:
https://doaj.org/article/57ff500d3589400986992b0e514a52c8
Publikováno v:
The Journal of Physical Chemistry B. 127:3616-3623
Autor:
Daniele Di Bari, Stepan Timr, Marianne Guiral, Marie-Thérèse Giudici-Orticoni, Tilo Seydel, Christian Beck, Caterina Petrillo, Philippe Derreumaux, Simone Melchionna, Fabio Sterpone, Judith Peters, Alessandro Paciaroni
Publikováno v:
ACS Central Science
ACS Central Science, 2023, ⟨10.1021/acscentsci.2c01078⟩
ACS Central Science, 2023, ⟨10.1021/acscentsci.2c01078⟩
International audience; Temperature variations have a big impact on bacterial metabolism and death, yet an exhaustive molecular picture of these processes is still missing. For instance, whether thermal death is determined by the deterioration of the
Publikováno v:
The Journal of Physical Chemistry B. 126:10317-10326
Publikováno v:
Proteins: Structure, Function, and Bioinformatics.
Publikováno v:
Proteins: Structure, Function, and Bioinformatics.
Autor:
Emeline Laborie, Simon Ebbinghaus, Roland Pollak, Fabio Sterpone, Sara Ribeiro, Stepan Timr, Mailin Becker, Nirnay Samanta
Publikováno v:
Journal of the American Chemical Society. 143:19909-19918
Stress granules (SGs) are among the most studied membraneless organelles that form upon heat stress (HS) to sequester unfolded, misfolded, or aggregated protein, supporting protein quality control (PQC) clearance. The folding states that are primaril
Probing the structures of amyloid-beta (Aβ) peptides in the early steps of aggregation is extremely difficult experimentally and computationally. Yet, this knowledge is extremely important as small oligomers are the most toxic species. Experiments a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf1b62290e8b6119c0b2c1da47d2b27a
https://doi.org/10.22541/au.167108799.96485165/v1
https://doi.org/10.22541/au.167108799.96485165/v1