Výsledky vyhledávání - "Fabio Rancati"

Mental and physical health in family members of substance users: A scoping review

Autor: Marco Di Sarno, Fabio Rancati, Raffaella Calati, Rossella Di Pierro, Valentina De Candia, F Madeddu

Background Due to the high pressure they sustain, family members of substance users are thought to experience negative consequences in mental and physical health. This scoping review provided a comprehensive overview on the mental and physical health

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ff59f2e42b03d79479eccf6b70d302
http://hdl.handle.net/10281/295513

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Discovery of a novel class of inhaled dual pharmacology muscarinic antagonist and β

Autor: Fabio, Rancati, Ian D, Linney, Andrea, Rizzi, Maurizio, Delcanale, Chris K, Knight, Wolfgang, Schmidt, Fiorella, Pastore, Benedetta, Riccardi, Valentina, Mileo, Chiara, Carnini, Nicola, Cesari, Wesley P, Blackaby, Riccardo, Patacchini, Laura, Carzaniga

Publikováno v: Bioorganicmedicinal chemistry letters. 41

The targeting of both the muscarinic and β-adrenergic pathways is a well validated therapeutic approach for the treatment of chronic obstructive pulmonary disease (COPD). In this communication we report our effort to incorporate two pharmacologies i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::99df3b0c884d5696f26973b1a0152ad6
https://pubmed.ncbi.nlm.nih.gov/33753262

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Discovery of a novel class of inhaled dual pharmacology muscarinic antagonist and β2 agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD)

Autor: Nicola Cesari, Laura Carzaniga, Ian Linney, Fiorella Pastore, Valentina Mileo, Riccardo Patacchini, Chiara Carnini, Wolfgang Schmidt, Maurizio Delcanale, Andrea Rizzi, Wesley Blackaby, Benedetta Riccardi, Fabio Rancati, Chris Knight

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 41:127975

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::045974f8add23f9443a5e55b04948b7d
https://doi.org/10.1016/j.bmcl.2021.127975

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Preparation of Sterically Demanding 2,2-Disubstituted-2-Hydroxy Acids by Enzymatic Hydrolysis

Autor: Laura Carzaniga, Francesco Molinari, Immacolata Serra, Roberta Mazzucato, Andrea Pinto, Martina Letizia Contente, Fabio Rancati, Diego Romano

Publikováno v: Catalysts, Vol 9, Iss 2, p 113 (2019)
Catalysts
Volume 9
Issue 2

Preparation of optically-pure derivatives of 2-hydroxy-2-(3-hydroxyphenyl)-2-phenylacetic acid of general structure 2 was accomplished by enzymatic hydrolysis of the correspondent esters. A screening with commercial hydrolases using the methyl ester

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c06654055984523dbf36550cfbcb995
https://www.mdpi.com/2073-4344/9/2/113

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Novel Pyrrolidine Derivatives of Budesonide as Long Acting Inhaled Corticosteroids for the Treatment of Pulmonary Inflammatory Diseases

Autor: Alessandro Fioni, Anna Maria Capelli, Chiara Carnini, Gessica Marchini, Fabio Rancati, Valentina Cenacchi, Eleonora Ghidini, Fabrizio Facchinetti

Publikováno v: Journal of medicinal chemistry. 61(11)

Inhaled corticosteroids (ICSs) represent the first line therapy for the treatment of asthma and are also extensively utilized in chronic obstructive pulmonary disease. Our goal was to develop a new ICS with a basic group, which can allow solid state

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e55945d31dfd4ca3b098cce803602cf
https://pubmed.ncbi.nlm.nih.gov/29741897

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Synthesis of 7-Substituted-(2,3-dihydro-1,4-benzodioxin-5-yl)-piperazine

Autor: Salvatore La Rosa, Steven Mark Bromidge, Stefania Gagliardi, Simone Del Sordo, Fabio Rancati, Carlo Parini

Publikováno v: Synthetic Communications. 38:2507-2520

A simple and versatile method for the synthesis of 7-substituted (2,3-dihydro-1,4-benzodioxin-5-yl)-piperazines starting from easy available class of derivatives has been developed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bde1aa9ee0d37e4b234f8478c8b557e3
https://doi.org/10.1080/00397910802219148

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Personality Structure Features Associated with Early Dropout in Patients with Substance-Related Disorders and Comorbid Personality Disorders

Autor: Rossella Di Pierro, Fabio Madeddu, Emanuele Preti, S Dainese, Chiara Rottoli, Fabio Rancati

This study aims at investigating factors associated with early dropout in dual diagnosis patients, considering socio-demographic, diagnostic and personality structure variables. We hypothesized that the personality structure of the patient will show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff3e5c4545d13d1a95a2a2fdc292429
http://hdl.handle.net/10281/70129

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A soluble polymer-bound Evans’ chiral auxiliary: synthesis, characterization and use in cycloaddition reactions

Autor: Dario Pasini, Alessandro Galbiati, Giovanni Desimoni, Fabio Rancati, Giuseppe Faita, Paolo Quadrelli

Publikováno v: Tetrahedron: Asymmetry. 13:333-337

The synthesis of novel soluble polymer-supported optically-active oxazolidinone (Evans’ chiral auxiliary) with different chiral monomer/styrene ratios is described. The polymer was obtained in high yields and then functionalized with trans -crotoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dd63307232c2d77e4cb0993c22a4ef2
https://doi.org/10.1016/s0957-4166(02)00117-9

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