Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fabio Pibiri"'
Autor:
Rosalba Satta, Ekrem Maloku, Adrian Zhubi, Bashkim Kadriu, Alessandro Guidotti, Erbo Dong, Fabio Pibiri
Publikováno v:
Neuropsychopharmacology. 36:1366-1374
Nicotine improves cognitive performance and attention in both experimental animals and in human subjects, including patients affected by neuropsychiatric disorders. However, the specific molecular mechanisms underlying nicotine-induced behavioral cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e6cf922ad534f2eb9ac5eceb6457de
https://doi.org/10.1038/npp.2011.21
https://doi.org/10.1038/npp.2011.21
Autor:
Patricia Tueting, Bashkim Kadriu, Fabio Pibiri, John M. Davis, Erminio Costa, Alessandro Guidotti, Marin Veldic
Publikováno v:
NeuroReport. 21:543-548
Schizophrenia postmortem brain is characterized by gamma aminobutyric acid downregulation and by decreased dendritic spine density in frontal cortex. Protracted L-methionine treatment exacerbates schizophrenia symptoms, and our earlier work (Tremoliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604b1c30ef1571db75987dd96d6cfcb9
https://doi.org/10.1097/wnr.0b013e3283373126
https://doi.org/10.1097/wnr.0b013e3283373126
Autor:
Rosalba Satta, Ekrem Maloku, Adrian Zhubi, Erminio Costa, Alessandro Guidotti, Mihály Hajós, Fabio Pibiri
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16356-16361
Tobacco smoking is frequently abused by schizophrenia patients (SZP). The major synaptically active component inhaled from cigarettes is nicotine, hence the smoking habit of SZP may represent an attempt to use nicotine self-medication to correct ( i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f9b76069556bc3a12e0cbc05ba4412
https://doi.org/10.1073/pnas.0808699105
https://doi.org/10.1073/pnas.0808699105
Autor:
Bashkim Kadriu, Erminio Costa, Graziano Pinna, James Auta, Alessandro Guidotti, Fabio Pibiri, Alan P. Kozikowski
Publikováno v:
Proceedings of the National Academy of Sciences. 105:14169-14174
Diisopropyl fluorophosphate (DFP) causes neurotoxicity related to an irreversible inhibition of acetylcholinesterase (AChE). Management of this intoxication includes: ( i ) pretreatment with reversible blockers of AChE, ( ii ) blockade of muscarinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c323147fbb577f336262d9fa57f11d
https://doi.org/10.1073/pnas.0807172105
https://doi.org/10.1073/pnas.0807172105
Autor:
Roberto Carlos Agis-Balboa, Erminio Costa, Fabio Pibiri, Marianela Nelson, Alessandro Guidotti, Graziano Pinna
Publikováno v:
Neurochemical Research. 33:1990-2007
The neurosteroid allopregnanolone is a potent positive allosteric modulator of GABA action at GABA(A) receptors. Allopregnanolone is synthesized in the brain from progesterone by the sequential action of 5alpha-reductase type I (5alpha-RI) and 3alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc922c35bd559bc3455ec3b8ef8f3022
https://doi.org/10.1007/s11064-008-9718-5
https://doi.org/10.1007/s11064-008-9718-5
Publikováno v:
Proceedings of the National Academy of Sciences. 105:5567-5572
Mice subjected to social isolation (3–4 weeks) exhibit enhanced contextual fear responses and impaired fear extinction. These responses are time-related to a decrease of 5α-reductase type I (5α-RI) mRNA expression and allopregnanolone (Allo) leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe8fe2a90d675fbe19ff1525ce8e7ed
https://doi.org/10.1073/pnas.0801853105
https://doi.org/10.1073/pnas.0801853105
Publikováno v:
NeuroReport. 17:1537-1541
Anabolic androgenic steroid abuse triggers impulsive aggression, anxiety, and depression, which suggests a dysfunction of GABAergic neurotransmission. Socially isolated female mice that have received testosterone propionate (1.45 micromol/kg) treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c15482be34025faf614ff621eddc90
https://doi.org/10.1097/01.wnr.0000234752.03808.b2
https://doi.org/10.1097/01.wnr.0000234752.03808.b2
Autor:
Sara Lazzarotti, V. Benetti, Alfredo Vannacci, Tiziano Tuccinardi, Fabio Pibiri, M. Paola Castelli, Giuseppe Saccomanni, and Adriano Martinelli, Pier Luigi Ferrarini, Clementina Manera, T. Cavallini
Publikováno v:
Journal of Medicinal Chemistry. 49:5947-5957
On the basis of docking studies carried out using the recently published cannabinoid receptor models,35 new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives were designed, synthesized, and tested for their affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1840a6e8d0acd224c71849e7201d78
https://doi.org/10.1021/jm0603466
https://doi.org/10.1021/jm0603466
Publikováno v:
Scopus-Elsevier
Gamma-hydroxybutyric acid (GHB), a naturally occurring metabolite of gamma-aminobutyric acid (GABA), has been postulated to act as a specific agonist of GHB receptors and as well as a weak GABA(B) receptor agonist. To date, 6,7,8,9-tetrahydro-5-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03fd7c73da14fdcba6cbf8847e386c1
https://doi.org/10.1111/j.1527-3458.2004.tb00025.x
https://doi.org/10.1111/j.1527-3458.2004.tb00025.x
Autor:
Giovanni Addolorato, Giancarlo Colombo, Gian Luigi Gessa, Fabio Pibiri, Giovanni Vacca, Salvatore Serra, Roberta Agabio, Mauro A.M. Carai
Publikováno v:
Neurotoxicity Research. 6:403-414
The present paper describes the results of recent preclinical and clinical studies conducted in this laboratory in order to characterize the anti-alcohol properties of the GABA(B) receptor agonist, baclofen. At a preclinical level, the repeated admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ad520acbc3bb7ecf77f65c965da7bd
https://doi.org/10.1007/bf03033315
https://doi.org/10.1007/bf03033315