Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Fabio Papes"'
Autor:
Fabio Papes, Antonio P. Camargo, Janaina S. de Souza, Vinicius M. A. Carvalho, Ryan A. Szeto, Erin LaMontagne, José R. Teixeira, Simoni H. Avansini, Sandra M. Sánchez-Sánchez, Thiago S. Nakahara, Carolina N. Santo, Wei Wu, Hang Yao, Barbara M. P. Araújo, Paulo E. N. F. Velho, Gabriel G. Haddad, Alysson R. Muotri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-26 (2022)
Abstract Transcription Factor 4 (TCF4) has been associated with autism, schizophrenia, and other neuropsychiatric disorders. However, how pathological TCF4 mutations affect the human neural tissue is poorly understood. Here, we derive neural progenit
Externí odkaz:
https://doaj.org/article/7f4c4866201a4b0fb0158c28268eed74
Autor:
Pinar Mesci, Janaina S. de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W. Adams, Simoni H. Avansini, Roberto H. Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A. Szeto, Gabriela Goldberg, Patrick T. Bruck, Fabio Papes, Sumit K. Chanda, Alysson R. Muotri
Publikováno v:
PLoS Biology, Vol 20, Iss 11 (2022)
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by the World Health Organization (WHO). Early clinical symptomatology focused mainly
Externí odkaz:
https://doaj.org/article/d270539d16b945478c694db07d712953
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription factor widely expressed throughout the body and during neural development. Mutations in TCF4 cause a devastating autism spectrum disorder known as Pitt
Externí odkaz:
https://doaj.org/article/7733f28fa3a54f0dbf3e24c181f11e72
Autor:
Thiago Seike Nakahara, Vinicius Miessler de Andrade Carvalho, Mateus Augusto de Andrade Souza, Guilherme Ziegler Trintinalia, Fabio Papes
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100153- (2020)
Summary: This protocol combines fluorescent in situ hybridization and immunostaining to simultaneously detect, in histological sections from the same animal, subpopulations of neurons activated after two episodes of sensory stimulation. It allows the
Externí odkaz:
https://doaj.org/article/008245aa294f4a59bf15afae2ef8a589
Autor:
Vinicius Miessler de Andrade Carvalho, Thiago Seike Nakahara, Mateus Augusto de Andrade Souza, Leonardo Minete Cardozo, Guilherme Ziegler Trintinalia, Leonardo Granato Pissinato, José Otávio Venancio, Lisa Stowers, Fabio Papes
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108061- (2020)
Summary: The internal representation of sensory information via coherent activation of specific pathways in the nervous system is key to appropriate behavioral responses. Little is known about how chemical stimuli that elicit instinctive behaviors le
Externí odkaz:
https://doaj.org/article/dc0e0325389d4121bc33cc7e65aeb459
Autor:
Ximena Ibarra-Soria, Thiago S Nakahara, Jingtao Lilue, Yue Jiang, Casey Trimmer, Mateus AA Souza, Paulo HM Netto, Kentaro Ikegami, Nicolle R Murphy, Mairi Kusma, Andrea Kirton, Luis R Saraiva, Thomas M Keane, Hiroaki Matsunami, Joel Mainland, Fabio Papes, Darren W Logan
Publikováno v:
eLife, Vol 6 (2017)
The mouse olfactory sensory neuron (OSN) repertoire is composed of 10 million cells and each expresses one olfactory receptor (OR) gene from a pool of over 1000. Thus, the nose is sub-stratified into more than a thousand OSN subtypes. Here, we employ
Externí odkaz:
https://doaj.org/article/15a96e0e6af7466bb3e8a8110bb7da7a
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational psychiatry, vol 11, iss 1
Translational Psychiatry
Translational psychiatry, vol 11, iss 1
Translational Psychiatry
The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription factor widely expressed throughout the body and during neural development. Mutations in TCF4 cause a devastating autism spectrum disorder known as Pitt–Hopkin
Autor:
Luciana Simões Rafagnin, Marinho, Gabrielly Maria Denadai, Chiarantin, Juliane Midori, Ikebara, Débora Sterzeck, Cardoso, Théo Henrique, de Lima-Vasconcellos, Guilherme Shigueto Vilar, Higa, Mariana Sacrini Ayres, Ferraz, Roberto, De Pasquale, Silvia Honda, Takada, Fabio, Papes, Alysson R, Muotri, Alexandre Hiroaki, Kihara
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The use of antidepressants during pregnancy benefits the mother's well-being, but the effects of such substances on neurodevelopment remain poorly understood. Moreover, the consequences of early exposure to antidepressants may not be immediately appa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e4d02e3617d9ececd341a197ea623b
Autor:
Lori Broderick, Gwendolyn M. Clay, Robert H. Blum, Yang Liu, Rachael McVicar, Fabio Papes, Laela M. Booshehri, Ian G. Cowell, Caroline A. Austin, Christopher D. Putnam, Dan S. Kaufman
Publikováno v:
The Journal of allergy and clinical immunology. 149(6)
Hoffman syndrome is a syndromic, inborn error of immunity due to autosomal-dominant mutations in TOP2B, an essential gene required to alleviate topological stress during DNA replication and gene transcription. Although mutations identified in patient
Autor:
Pinar Mesci, Janaina S. de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W. Adams, Simoni H. Avansini, Roberto H. Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A. Szeto, Gabriela Goldberg, Patrick T. Bruck, Fabio Papes, Sumit K. Chanda, Alysson R. Muotri
Publikováno v:
PLoS biology, vol 20, iss 11
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by the World Health Organization (WHO). Early clinical symptomatology focused mainly