Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Fabio Palombo"'
Autor:
Antonella Conforti, Elisa Sanchez, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Fabio Palombo, Emanuela D’Acunto, Alessia Muzi, Giuseppe Roscilli, Yuhua Sun, Brian Viscount, James Hayward, Clay Shorrock, Diego G. Diel, Joseph A. Impellizeri, Luigi Aurisicchio
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 238-248 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of the COVID-19 pandemic, has been shown to infect a wide range of animal species, especially mammals, and besides human-to-human transmission, human-to-animal transmis
Externí odkaz:
https://doaj.org/article/8cf94db2dc954d46883132f49d55d11a
Autor:
Antonella Conforti, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Clay Shorrock, James A. Hayward, Yuhua Sun, Ben Minghwa Liang, Fabio Palombo, Brian Viscount, Luigi Aurisicchio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-13 (2022)
Abstract Background DNA-based vaccines represent a simple, safe and promising strategy for harnessing the immune system to fight infectious diseases as well as various forms of cancer and thus are considered an important tool in the cancer immunother
Externí odkaz:
https://doaj.org/article/c3f61ccbcf314d79b2dad66b10fb3300
Autor:
Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Antonella Conforti, Gennaro Ciliberto, Luigi Aurisicchio, Fabio Palombo
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Immune checkpoint inhibitors (ICI) based on anti-CTLA-4 (αCTLA-4) and anti-PD1 (αPD1) are being tested in combination with different therapeutic approaches including other immunotherapies such as neoantigen cancer vaccines (NCV). Here we e
Externí odkaz:
https://doaj.org/article/fb0d0521420643b58531e5cd5ee96758
Autor:
Federico D’Alessio, Lucia Lione, Erika Salvatori, Federica Bucci, Alessia Muzi, Giuseppe Roscilli, Mirco Compagnone, Eleonora Pinto, Gianfranco Battistuzzi, Antonella Conforti, Luigi Aurisicchio, Fabio Palombo
Publikováno v:
Vaccines, Vol 11, Iss 3, p 678 (2023)
DNA integrity is a key issue in gene therapy and genetic vaccine approaches based on plasmid DNA. In contrast to messenger RNA that requires a controlled cold chain for efficacy, DNA molecules are considered to be more stable. In this study, we chall
Externí odkaz:
https://doaj.org/article/2856ce0df8aa476781eb9ce4d224582a
Autor:
Alice Massacci, Eleonora Sperandio, Lorenzo D’Ambrosio, Mariano Maffei, Fabio Palombo, Luigi Aurisicchio, Gennaro Ciliberto, Matteo Pallocca
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-7 (2020)
Abstract Background Tracking the genetic variability of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) is a crucial challenge. Mainly to identify target sequences in order to generate robust vaccines and neutralizing monoclonal antibodi
Externí odkaz:
https://doaj.org/article/467bef07d6ac449dbed9b6befc7719f3
Autor:
Mirco Compagnone, Eleonora Pinto, Erika Salvatori, Lucia Lione, Antonella Conforti, Silvia Marchese, Micol Ravà, Kathryn Ryan, Yper Hall, Emma Rayner, Francisco J. Salguero, Jemma Paterson, Matteo Iannacone, Raffaele De Francesco, Luigi Aurisicchio, Fabio Palombo
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1178 (2022)
The COVID-19 pandemic is entering a new era with the approval of many SARS-CoV-2 vaccines. In spite of the restoration of an almost normal way of life thanks to the immune protection elicited by these innovative vaccines, we are still facing high vir
Externí odkaz:
https://doaj.org/article/66b84d88d8474a12bacb290c702f7d51
Autor:
Giovanni Salvatori, Laura Luberto, Mariano Maffei, Luigi Aurisicchio, Giuseppe Roscilli, Fabio Palombo, Emanuele Marra
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-3 (2020)
Abstract COVID-19 has rapidly spread all over the world, progressing into a pandemic. This situation has urgently impelled many companies and public research institutes to concentrate their efforts on research for effective therapeutics. Here, we out
Externí odkaz:
https://doaj.org/article/24ff44bc513e44619d1a1c8e72df4d30
Autor:
Matteo Pallocca, Davide Angeli, Fabio Palombo, Francesca Sperati, Michele Milella, Frauke Goeman, Francesca De Nicola, Maurizio Fanciulli, Paola Nisticò, Concetta Quintarelli, Gennaro Ciliberto
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-8 (2019)
Abstract Background There are no accepted universal biomarkers capable to accurately predict response to immuno-checkpoint inhibitors (ICI). Although recent literature has been flooded with studies on ICI predictive biomarkers, available data show th
Externí odkaz:
https://doaj.org/article/b489c74a3a514dcdba84c262daf9eed8
Autor:
Luigi Aurisicchio, Erika Salvatori, Lucia Lione, Silvio Bandini, Matteo Pallocca, Roberta Maggio, Maurizio Fanciulli, Francesca De Nicola, Frauke Goeman, Gennaro Ciliberto, Antonella Conforti, Laura Luberto, Fabio Palombo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Personalized cancer vaccines based on neoantigens have reached the clinical trial stage in melanoma. Different vaccination protocols showed efficacy in preclinical models without a clear indication of the quality and the number of
Externí odkaz:
https://doaj.org/article/2d2cec89e01e4ec9871150c20f7cdb51
Autor:
Lucia Lione, Erika Salvatori, Adriana Petrazzuolo, Alice Massacci, Roberta Maggio, Antonella Conforti, Mirco Compagnone, Luigi Aurisicchio, Gennaro Ciliberto, Fabio Palombo
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Cancer is a heterogeneous disease and its treatment remains unsatisfactory with inconstant therapeutic responses. This variability could be related, at least in part, to different and highly personalized gut microbiota compositions. Different studies
Externí odkaz:
https://doaj.org/article/d41c219028fd4c74b7f18129fa62b6fe