Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fabio M. Simoes de Souza"'
Autor:
Ming Ma, Gregory L. Futia, Fabio M. Simoes de Souza, Baris N. Ozbay, Isabel Llano, Emily A. Gibson, Diego Restrepo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
This study shows that cerebellar molecular layer interneurons (MLIs) develop responses encoding for identity of the stimulus in an associative learning task. Chemogenetic inhibition of MLIs decreased the ability of mice to discriminate stimuli sugges
Externí odkaz:
https://doaj.org/article/e939dd0379a7491e9b71c703b9d39a49
Autor:
Elizabeth A Gould, Nicolas Busquet, Douglas Shepherd, Robert M Dietz, Paco S Herson, Fabio M Simoes de Souza, Anan Li, Nicholas M George, Diego Restrepo, Wendy B Macklin
Publikováno v:
eLife, Vol 7 (2018)
Myelin, the insulating sheath around axons, supports axon function. An important question is the impact of mild myelin disruption. In the absence of the myelin protein proteolipid protein (PLP1), myelin is generated but with age, axonal function/main
Externí odkaz:
https://doaj.org/article/12b48b733414432e91d57f613adc033b
Publikováno v:
Acta Physiologica. 234
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950c80b738b5e4055b660ad3c4a1a641
https://doi.org/10.1111/apha.13755
https://doi.org/10.1111/apha.13755
Publikováno v:
Acta Physiologica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c6ecf3d4b069a53e8fdb1c9e1d97f9b
https://doi.org/10.1111/apha.13669
https://doi.org/10.1111/apha.13669
Publikováno v:
Journal of Visualized Experiments.
Computational modeling of diffusion and reaction of chemical species in a three-dimensional (3D) geometry is a fundamental method to understand the mechanisms of synaptic plasticity in dendritic spines. In this protocol, the detailed 3D structure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9650f410e9c2d2acbab088abb1ed7c
https://doi.org/10.3791/60896
https://doi.org/10.3791/60896
Autor:
Isabel Llano, Fabio M Simoes de Souza, Ming Ma, Emily A. Gibson, Diego Restrepo, Gregory L. Futia, Baris N. Ozbay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
The cerebellum plays a crucial role in sensorimotor and associative learning. However, the contribution of molecular layer interneurons (MLIs) to these processes is not well understood. We used two-photon microscopy to study the role of ensembles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dda10f9840c11db06108265086a4ea
https://doi.org/10.1101/2019.12.14.876201
https://doi.org/10.1101/2019.12.14.876201
Autor:
Paco S. Herson, Nicolas Busquet, Diego Restrepo, Elizabeth A. Gould, Fabio M Simoes de Souza, Wendy B. Macklin, Robert M. Dietz, Douglas P. Shepherd, Anan Li, Nicholas M. George
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a61d4b1d552ab1c4931b167d70719a
https://doi.org/10.7554/elife.34783.036
https://doi.org/10.7554/elife.34783.036
Publikováno v:
International journal of neural systems. 28(5)
Mirror neurons fire action potentials both when the agent performs a certain behavior and watches someone performing a similar action. Here, we present an original mirror neuron model based on the spike-timing-dependent plasticity (STDP) between two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d74e6a48f1956dfdd5401f9b2a3e5bf
https://pubmed.ncbi.nlm.nih.gov/29297264
https://pubmed.ncbi.nlm.nih.gov/29297264
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Frequently, a common chemical entity triggers opposite cellular processes, which implies that the components of signalling networks must detect signals not only through their chemical natures, but also through their dynamic properties. To gain insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710a16a36632f1c1bdd94915172f92af
Publikováno v:
Neurocomputing. 70:1663-1667
We developed a detailed computational model of an olfactory sensory neuron to investigate the functional properties of the sensory adaptation in the peripheral olfactory system. The model consists of a system of first-order differential equations tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7c4ef53ce50f1efc47292b8327a668
https://doi.org/10.1016/j.neucom.2006.10.090
https://doi.org/10.1016/j.neucom.2006.10.090