Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Fabio Luciani"'
Autor:
Dmitrii Shek, Bo Gao, Hema Mahajan, Adnan Nagrial, Matteo S. Carlino, Fabio Luciani, Scott A. Read, Golo Ahlenstiel
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101189- (2024)
Externí odkaz:
https://doaj.org/article/e2af2ae363bc4a0f897578e366061bc5
Autor:
Raymond Hall Yip Louie, Curtis Cai, Jerome Samir, Mandeep Singh, Ira W. Deveson, James M. Ferguson, Timothy G. Amos, Helen Marie McGuire, Kavitha Gowrishankar, Thiruni Adikari, Robert Balderas, Martina Bonomi, Marco Ruella, David Bishop, David Gottlieb, Emily Blyth, Kenneth Micklethwaite, Fabio Luciani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Chimeric antigen receptor (CAR) T cell therapy is effective in treating B cell malignancies, but factors influencing the persistence of functional CAR+ T cells, such as product composition, patients’ lymphodepletion, and immune reconstitut
Externí odkaz:
https://doaj.org/article/012a087278b14da7bf94cbc8b4123134
Autor:
Golo Ahlenstiel, Matteo Carlino, Bo Gao, Adnan Nagrial, Hema Mahajan, Fabio Luciani, Dmitrii Shek, Scott Read
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e32e32c95f504657a849e914b5a9f641
Autor:
Curtis Cai, Jerome Samir, Mehdi R. Pirozyan, Thiruni N. Adikari, Money Gupta, Preston Leung, Brendan Hughes, Willem Van der Byl, Simone Rizzetto, Auda Elthala, Elizabeth Keoshkerian, Jean-Louis Palgen, Timothy Peters, Thi H. O. Nguyen, Raymond Louie, Katherine Kedzierska, Silvana Gaudieri, Rowena A. Bull, Andrew R. Lloyd, Fabio Luciani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The early immune response following exposure to HCV is not fully explored. Here the authors use single cell analysis and immune profiling to relate the infection sequence and immune response to early HCV infection showing that exhausted phenotypes of
Externí odkaz:
https://doaj.org/article/588f772ffcbf4737b2226e6c72bd6b81
Autor:
Yanping Yang, Raymond Louie, Janusz Puc, Yogindra Vedvyas, Yago Alcaina, Irene M. Min, Matt Britz, Fabio Luciani, Moonsoo M. Jin
Publikováno v:
Cancers, Vol 15, Iss 23, p 5552 (2023)
Epithelial cell adhesion molecule (EpCAM) is a tumor-associated antigen that is frequently overexpressed in various carcinomas. We have developed chimeric antigen receptor (CAR) T cells specifically targeting EpCAM for the treatment of gastric cancer
Externí odkaz:
https://doaj.org/article/928eb59e70d34c83aecca3355fb6d78f
Autor:
Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James R. Torpy, Deborah Knight, Sinead Reading, Kevin Thia, Lisa A. Miosge, Debbie R. Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Exhausted T cells arise when chronic activation triggers functional defects. Here the authors show that chronic antigenic stimulation in both tumour and infection models induces the expression of EGR2, which drives and stabilises exhausted cell epige
Externí odkaz:
https://doaj.org/article/835402bfc1a5448994d0c742c77cfabd
Autor:
Luca Hensen, Patricia T. Illing, E. Bridie Clemens, Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Nicole A. Mifsud, Andrea T. Nguyen, Christopher Szeto, Brendon Y. Chua, Hanim Halim, Simone Rizzetto, Fabio Luciani, Liyen Loh, Emma J. Grant, Phillipa M. Saunders, Andrew G. Brooks, Steve Rockman, Tom C. Kotsimbos, Allen C. Cheng, Michael Richards, Glen P. Westall, Linda M. Wakim, Thomas Loudovaris, Stuart I. Mannering, Michael Elliott, Stuart G. Tangye, David C. Jackson, Katie L. Flanagan, Jamie Rossjohn, Stephanie Gras, Jane Davies, Adrian Miller, Steven Y. C. Tong, Anthony W. Purcell, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The immunology of Indigenous populations is generally understudied outside the context of diseases that are prevalent in these communities. Here the authors identify prevalence of influenza CD8+ T cell epitopes in an Indigenous Australian population
Externí odkaz:
https://doaj.org/article/a3a6a4c017e544c7b83819f5cde0c3d5
Autor:
Rowena A. Bull, Thiruni N. Adikari, James M. Ferguson, Jillian M. Hammond, Igor Stevanovski, Alicia G. Beukers, Zin Naing, Malinna Yeang, Andrey Verich, Hasindu Gamaarachchi, Ki Wook Kim, Fabio Luciani, Sacha Stelzer-Braid, John-Sebastian Eden, William D. Rawlinson, Sebastiaan J. van Hal, Ira W. Deveson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nanopore sequencing (ONT) has been used in SARS-CoV-2 studies, however adoption of ONT for SARS-CoV-2 surveillance has been limited due to common concerns around sequencing accuracy. Here, the authors perform a comprehensive evaluation of ONT analyti
Externí odkaz:
https://doaj.org/article/d77df009f76046bb9bfe8be6833f8152
Autor:
Thiruni N. Adikari, Francesca Di Giallonardo, Preston Leung, Alba Grifoni, Alex Sette, Daniela Weiskopf, Rowena A. Bull, Fabio Luciani
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Cytotoxic CD8+ T cells are key for immune protection against viral infections. The breadth and cross-reactivity of these responses are important against rapidly mutating RNA viruses, such as dengue (DENV), yet how viral diversity affect T ce
Externí odkaz:
https://doaj.org/article/51745d141be148b08de2cd69f032174f
Autor:
Jennifer Massey, Katherine Jackson, Mandeep Singh, Brendan Hughes, Barbara Withers, Carole Ford, Melissa Khoo, Kevin Hendrawan, John Zaunders, Bénédicte Charmeteau-De Muylder, Rémi Cheynier, Fabio Luciani, David Ma, John Moore, Ian Sutton
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autologous haematopoietic stem cell transplantation (AHSCT) is a vital therapeutic option for patients with highly active multiple sclerosis (MS). Rates of remission suggest AHSCT is the most effective form of immunotherapy in controlling the disease
Externí odkaz:
https://doaj.org/article/806db025e95b40b88aee3c8ef34ecd0b