Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Fabio Gualtieri"'
Autor:
Eva-Lotta von Rüden, Fabio Gualtieri, Katharina Schönhoff, Maria Reiber, Fabio Wolf, Wolfgang Baumgärtner, Florian Hansmann, Andrea Tipold, Heidrun Potschka
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-14 (2020)
Abstract Background Cumulating evidence from rodent models points to a pathophysiological role of inflammatory signaling in the epileptic brain with Toll-like receptor-4 signaling acting as one key factor. However, there is an apparent lack of inform
Externí odkaz:
https://doaj.org/article/1b13645435504471a5438fa249104a85
Autor:
Valentina Di Liberto, R. Maarten van Dijk, Matthias Brendel, Ann-Marie Waldron, Christina Möller, Ines Koska, Isabel Seiffert, Fabio Gualtieri, Franz Josef Gildehaus, Barbara von Ungern-Sternberg, Magdalena Lindner, Sibylle Ziegler, Rupert Palme, Rainer Hellweg, Peter Gass, Peter Bartenstein, Heidrun Potschka
Publikováno v:
Neurobiology of Disease, Vol 118, Iss , Pp 9-21 (2018)
Psychiatric comorbidities are prevalent in patients with epilepsy and greatly contribute to the overall burden of disease. The availability of reliable biomarkers to diagnose epilepsy-associated comorbidities would allow for effective treatment and i
Externí odkaz:
https://doaj.org/article/5acfa05fe62c4f00a97d52eaf26cf3d3
Autor:
Michael Keck, Ganna Androsova, Fabio Gualtieri, Andreas Walker, Eva-Lotta von Rüden, Vera Russmann, Cornelia A. Deeg, Stefanie M. Hauck, Roland Krause, Heidrun Potschka
Publikováno v:
Neurobiology of Disease, Vol 105, Iss , Pp 164-178 (2017)
Despite intense research efforts, the knowledge about the mechanisms of epileptogenesis and epilepsy is still considered incomplete and limited. However, an in-depth understanding of molecular pathophysiological processes is crucial for the rational
Externí odkaz:
https://doaj.org/article/b09bb45ef2fc4963888a49748a876b56
Autor:
Fabio Gualtieri, Catherine Brégère, Grace C. Laws, Elena A. Armstrong, Nicholas J. Wylie, Theo T. Moxham, Raphael Guzman, Timothy Boswell, Tom V. Smulders
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Adult hippocampal neurogenesis (AHN) in the dentate gyrus is known to respond to environmental enrichment, chronic stress, and many other factors. The function of AHN may vary across the septo-temporal axis of the hippocampus, as different subdivisio
Externí odkaz:
https://doaj.org/article/60e6a871f13c4996bfcda7c583376f77
Autor:
Chiara Lucchi, Giulia Curia, Jonathan Vinet, Fabio Gualtieri, Elena Bresciani, Vittorio Locatelli, Antonio Torsello, Giuseppe Biagini
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72716 (2013)
In models of status epilepticus ghrelin displays neuroprotective effects mediated by the growth hormone secretagogue-receptor 1a (GHS-R1a). This activity may be explained by anticonvulsant properties that, however, are controversial. We further inves
Externí odkaz:
https://doaj.org/article/79bdfe551ac5474d90ff70904034e29c
Autor:
Fabio Gualtieri, Eva-Lotta von Rüden, Marta Nowakowska, Heidrun Potschka, Wolfgang Baumgärtner, Andrea Tipold, Florian Hansmann
Publikováno v:
Neuroscience. 429:156-172
Unfolded protein response is a signaling cascade triggered by misfolded proteins in the endoplasmic reticulum. Heat shock protein H4 (HSPH4) and A5 (HSPA5) are two chaperoning proteins present within the organelle, which target misfolded peptides dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042b19fa0906f5da3120e0231613c2c1
https://doi.org/10.1016/j.neuroscience.2019.12.015
https://doi.org/10.1016/j.neuroscience.2019.12.015
Autor:
Francesca Testa, Francesco Fontana, Federico Pollastri, Johanna Chester, Marco Leonelli, Francesco Giaroni, Fabio Gualtieri, Federico Bolelli, Elena Mancini, Maurizio Nordio, Paolo Sacco, Giulia Ligabue, Silvia Giovanella, Maria Ferri, Gaetano Alfano, Loreto Gesualdo, Simonetta Cimino, Gabriele Donati, Costantino Grana, Riccardo Magistroni
Digital pathology and artificial intelligence offer new opportunities for automatic histologic scoring. We applied a deep learning approach to IgA nephropathy biopsy images to develop an automatic histologic prognostic score, assessed against ground
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac7d8f42fad50afdd3e42be5e449609
https://hdl.handle.net/11380/1291987
https://hdl.handle.net/11380/1291987
Publikováno v:
Neuroscience. 415:44-58
Temporal lobe epilepsy is triggered by an initial insult, such as status epilepticus, that initiates the process of epilepsy development. Heat shock protein 70 (Hsp70) is a ubiquitously expressed molecular chaperone, involved in the inflammatory resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00980bf1d9b6b3795e4aa2c0c3120527
https://doi.org/10.1016/j.neuroscience.2019.06.031
https://doi.org/10.1016/j.neuroscience.2019.06.031
Autor:
Marta Nowakowska, Michael Oglesbee, Fabio Wolf, Michael Keck, Eva-Lotta von Rüden, Fabio Gualtieri, Heidrun Potschka
Publikováno v:
Neuroscience. 386:108-120
Strong evidence exists that Toll-like receptor (TLR)-mediated effects on microglia functional states can promote ictogenesis and epileptogenesis. So far, research has focused on the role of high-mobility group box protein 1 as an activator of TLRs. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13e12be66e2a905ea22b1b20544bc31
https://doi.org/10.1016/j.neuroscience.2018.06.031
https://doi.org/10.1016/j.neuroscience.2018.06.031
Autor:
Fabio Gualtieri, Victoria Sandilands, Tom V. Smulders, Georgia K. Longmoor, Elena A. Armstrong, Timothy Boswell, R. B. D'Eath
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
In the mammalian brain, adult hippocampal neurogenesis (AHN) is suppressed by chronic stress, primarily at the ventral pole of the hippocampus. Based upon anatomy, we hypothesise that the caudal pole of the avian Hippocampal Formation (HF) presents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da442c7342eda46f86b7b7ef7efa3b24
https://doi.org/10.1038/s41598-019-43584-x
https://doi.org/10.1038/s41598-019-43584-x