Výsledky vyhledávání - "Fabio Giuseppe Liberante"

Akademický článek

Post-diagnostic antipsychotic use and cancer mortality: a population based cohort study

Autor: Blánaid M. Hicks, John Busby, Ken Mills, Francis A. O’Neil, Stuart A. McIntosh, Shu-Dong Zhang, Fabio Giuseppe Liberante, Chris R. Cardwell

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)

Abstract Background Many antipsychotics elevate prolactin, a hormone implicated in breast cancer aetiology however no studies have investigated antipsychotic use in patients with breast cancer. This study investigated if antipsychotic use is associat

Externí odkaz: https://doaj.org/article/9ff8bc7343754e999d071091598c0e07

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Akademický článek

Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study

Autor: John Busby, Ken Mills, Shu-Dong Zhang, Fabio Giuseppe Liberante, Chris R. Cardwell

Publikováno v: Breast Cancer Research, Vol 20, Iss 1, Pp 1-10 (2018)

Abstract Background Nearly 50% of breast cancer patients suffer from depression or anxiety. Selective serotonin reuptake inhibitors (SSRIs), the first-line pharmacological treatment for depression, have been implicated in breast cancer development th

Externí odkaz: https://doaj.org/article/8e5f24e0995c42c491b03bac093d2fae

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Prediction of prime editing insertion efficiencies using sequence features and DNA repair determinants

Autor: Jonas Koeppel, Juliane Weller, Elin Madli Peets, Ananth Pallaseni, Ivan Kuzmin, Uku Raudvere, Hedi Peterson, Fabio Giuseppe Liberante, Leopold Parts

Publikováno v: Nature Biotechnology.

Most short sequences can be precisely written into a selected genomic target using prime editing; however, it remains unclear what factors govern insertion. We design a library of 3,604 sequences of various lengths and measure the frequency of their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c713398ca7bcb093a7bd3ecbfe465931
https://doi.org/10.1038/s41587-023-01678-y

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From kilobases to megabases: Design and delivery of large DNA constructs into mammalian genomes

Autor: Tom Ellis, Fabio Giuseppe Liberante

Publikováno v: Current Opinion in Systems Biology. 25:1-10

As DNA synthesis has become cheaper, it has made assembly of larger and larger genes possible. To fully realise this opportunity for a new era of synthetic biology in mammals, a number of gaps are beginning to be addressed in the design, synthesis, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af68edf6a28627ec0bb09b6555bd690c
https://doi.org/10.1016/j.coisb.2020.11.003

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Predicting efficiency of writing short sequences into the genome using prime editing

Autor: Ananth Pallaseni, Fabio Giuseppe Liberante, Elin Madli Peets, Jonas Koeppel, Leopold Parts, Juliane Weller

SUMMARYShort sequences can be precisely written into a selected genomic target using prime editing. This ability facilitates protein tagging, correction of pathogenic deletions, and many other exciting applications. However, it remains unclear what t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89034d65ff747e099f5b079f1314765a
https://doi.org/10.1101/2021.11.10.468024