Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Fabio Fuligni"'
Autor:
Samuele Renzi, Fatimah Algawahmed, Scott Davidson, Karin P. S. Langenberg, Fabio Fuligni, Salah Ali, Nathaniel Anderson, Ledia Brunga, Jack Bartram, Mohamed Abdelhaleem, Ahmed Naqvi, Kassa Beimnet, Andre Schuh, Anne Tierens, David Malkin, Adam Shlien, Mary Shago, Anita Villani
Publikováno v:
Current Oncology, Vol 30, Iss 7, Pp 5946-5952 (2023)
ETV6-ABL1 gene fusion is a rare genetic rearrangement in a variety of malignancies, including myeloproliferative neoplasms (MPN), acute lymphoblastic leukemia (ALL), and acute myeloid leukemia (AML). Here, we report the case of a 16-year-old male dia
Externí odkaz:
https://doaj.org/article/a592fb16ae0b494781fe3064b7d6424d
Autor:
Fabio Fuligni, Robert Thaenert, Aidan Hennigan, Duncan Kilburn, Valeriya Gaysinskaya, Egor Dolzhenko, Guilherme De Sena Brandine, Sarah Kingan, Jason Evans, Danuta Hietpas, Hannah White, Tamara Smith, Timothy Looney, Ray Veeraraghavan, Tina Hambuch-Hawks, Christopher Elzinga, Meaghan Russell
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101120- (2024)
Externí odkaz:
https://doaj.org/article/605140cf4b3c4596b6038a41f352dd79
Autor:
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D. Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M. Abegglen, Daniel Albertson, Jonathan L. Finlay, Jordan R. Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B. Alexandrov, Gino R. Somers, Joshua D. Schiffman, Varda Rotter, David Malkin, Adam Shlien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Li-Fraumeni syndrome (LFS) is associated with pathogenic germline TP53 variants and predisposes patients to cancer; understanding the evolution and drivers of LFS-related tumours remains crucial. Here, the authors analyse 22 LFS tumours using whole-g
Externí odkaz:
https://doaj.org/article/6313943fa94246f49c0f01dd1873ed40
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival
Autor:
Nathaniel D. Anderson, Yael Babichev, Fabio Fuligni, Federico Comitani, Mehdi Layeghifard, Rosemarie E. Venier, Stefan C. Dentro, Anant Maheshwari, Sheena Guram, Claire Wunker, J. Drew Thompson, Kyoko E. Yuki, Huayun Hou, Matthew Zatzman, Nicholas Light, Marcus Q. Bernardini, Jay S. Wunder, Irene L. Andrulis, Peter Ferguson, Albiruni R. Abdul Razak, Carol J. Swallow, James J. Dowling, Rima S. Al-Awar, Richard Marcellus, Marjan Rouzbahman, Moritz Gerstung, Daniel Durocher, Ludmil B. Alexandrov, Brendan C. Dickson, Rebecca A. Gladdy, Adam Shlien
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Heterogeneity in leiomyosarcomas (LMS) makes treatment of the disease challenging. Here the authors analyze LMS heterogeneity and molecular LMS subtypes using genomics and transcriptomics, finding origins in distinct lineages and associations with su
Externí odkaz:
https://doaj.org/article/c08bf52065ac4dcd90672db6a2810128
Autor:
Federica Loscocco, Giuseppe Visani, Annamaria Ruzzo, Irene Bagaloni, Fabio Fuligni, Sara Galimberti, Antonello Di Paolo, Fabio Stagno, Patrizia Pregno, Mario Annunziata, Antonella Gozzini, Sara Barulli, Elisa Gabucci, Mauro Magnani, Alessandro Isidori
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tyrosine kinase inhibitors (TKIs) have radically changed the outcome of chronic myeloid leukemia (CML) patients in the last 20 years. Moreover, the advent of second generation TKIs, namely nilotinib and dasatinib, have largely increased the number of
Externí odkaz:
https://doaj.org/article/43ad989d92e946a3a061a8934831529a
Autor:
Maria Rosaria Sapienza, Francesco Abate, Federica Melle, Stefania Orecchioni, Fabio Fuligni, Maryam Etebari, Valentina Tabanelli, Maria Antonella Laginestra, Alessandro Pileri, Giovanna Motta, Maura Rossi, Claudio Agostinelli, Elena Sabattini, Nicola Pimpinelli, Mauro Truni, Brunangelo Falini, Lorenzo Cerroni, Giovanna Talarico, Rossana Piccioni, Stefano Amente, Valentina Indio, Giuseppe Tarantino, Francesco Brundu, Marco Paulli, Emilio Berti, Fabio Facchetti, Gaetano Ivan Dellino, Francesco Bertolini, Claudio Tripodo, Raul Rabadan, Stefano A. Pileri
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective therapy. In order to identify genetic alterations useful for a new treatment design, we used whole-exome sequen
Externí odkaz:
https://doaj.org/article/01681f3120c147ab8e9eafb72e1bb596
Autor:
Adam Shlien, Keiran Raine, Fabio Fuligni, Roland Arnold, Serena Nik-Zainal, Serge Dronov, Lira Mamanova, Andrej Rosic, Young Seok Ju, Susanna L. Cooke, Manasa Ramakrishna, Elli Papaemmanuil, Helen R. Davies, Patrick S. Tarpey, Peter Van Loo, David C. Wedge, David R. Jones, Sancha Martin, John Marshall, Elizabeth Anderson, Claire Hardy, Violetta Barbashina, Samuel A.J.R. Aparicio, Torill Sauer, Øystein Garred, Anne Vincent-Salomon, Odette Mariani, Sandrine Boyault, Aquila Fatima, Anita Langerød, Åke Borg, Gilles Thomas, Andrea L. Richardson, Anne-Lise Børresen-Dale, Kornelia Polyak, Michael R. Stratton, Peter J. Campbell
Publikováno v:
Cell Reports, Vol 16, Iss 7, Pp 2032-2046 (2016)
Disordered transcriptomes of cancer encompass direct effects of somatic mutation on transcription, coordinated secondary pathway alterations, and increased transcriptional noise. To catalog the rules governing how somatic mutation exerts direct trans
Externí odkaz:
https://doaj.org/article/4492535398b04897a7bfaecb4a9c01d9
Autor:
Francesco Abate, Maria Raffaella Ambrosio, Lucia Mundo, Maria Antonella Laginestra, Fabio Fuligni, Maura Rossi, Sakellarios Zairis, Sara Gazaneo, Giulia De Falco, Stefano Lazzi, Cristiana Bellan, Bruno Jim Rocca, Teresa Amato, Elena Marasco, Maryam Etebari, Martin Ogwang, Valeria Calbi, Isaac Ndede, Kirtika Patel, David Chumba, Pier Paolo Piccaluga, Stefano Pileri, Lorenzo Leoncini, Raul Rabadan
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005158 (2015)
Endemic Burkitt lymphoma (eBL) is primarily found in children in equatorial regions and represents the first historical example of a virus-associated human malignancy. Although Epstein-Barr virus (EBV) infection and MYC translocations are hallmarks o
Externí odkaz:
https://doaj.org/article/5733963b8ab24a61b54eeb99cf03c4ed
Autor:
Pier Paolo Piccaluga, Claudio Agostinelli, Fabio Fuligni, Simona Righi, Claudio Tripodo, Maria Carla Re, Alberto Clò, Anna Miserocchi, Silvia Morini, Marisa Gariglio, Gian Gaetano Ferri, Alberto Rinaldi-Ceroni, Ottavio Piccin, Marco De Andrea, Stefano A. Pileri, Santo Landolfo, Davide Gibellini
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The interferon-inducible DNA sensor IFI16 is involved in the modulation of cellular survival, proliferation, and differentiation. In the hematopoietic system, IFI16 is consistently expressed in the CD34+ stem cells and in peripheral blood lymphocytes
Externí odkaz:
https://doaj.org/article/79b1eaf075e94380852eca3625ee107e
Autor:
Francesca Turroni, Clelia Peano, Daniel A Pass, Elena Foroni, Marco Severgnini, Marcus J Claesson, Colm Kerr, Jonathan Hourihane, Deirdre Murray, Fabio Fuligni, Miguel Gueimonde, Abelardo Margolles, Gianluca De Bellis, Paul W O'Toole, Douwe van Sinderen, Julian R Marchesi, Marco Ventura
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36957 (2012)
The human gastrointestinal tract (GIT) represents one of the most densely populated microbial ecosystems studied to date. Although this microbial consortium has been recognized to have a crucial impact on human health, its precise composition is stil
Externí odkaz:
https://doaj.org/article/4972798fa58542d19b4ce813f19411f3