A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility

Autor: Alessia Varone, Stefania Mariggiò, Manpreet Patheja, Vincenzo Maione, Antonio Varriale, Mariangela Vessichelli, Daniela Spano, Fabio Formiggini, Matteo Lo Monte, Nadia Brancati, Maria Frucci, Pompea Del Vecchio, Sabato D’Auria, Angela Flagiello, Clara Iannuzzi, Alberto Luini, Piero Pucci, Lucia Banci, Carmen Valente, Daniela Corda

Publikováno v: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)

Abstract Background Shp1, a tyrosine-phosphatase-1 containing the Src-homology 2 (SH2) domain, is involved in inflammatory and immune reactions, where it regulates diverse signalling pathways, usually by limiting cell responses through dephosphorylat

Externí odkaz: https://doaj.org/article/56f9ef9873944b5b84f148cb4d4fd815

MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma.

Autor: Pasqualino de Antonellis, Chiara Medaglia, Emilio Cusanelli, Immacolata Andolfo, Lucia Liguori, Gennaro De Vita, Marianeve Carotenuto, Annamaria Bello, Fabio Formiggini, Aldo Galeone, Giuseppe De Rosa, Antonella Virgilio, Immacolata Scognamiglio, Manuela Sciro, Giuseppe Basso, Johannes H Schulte, Giuseppe Cinalli, Achille Iolascon, Massimo Zollo

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24584 (2011)

Through negative regulation of gene expression, microRNAs (miRNAs) can function as oncosuppressors in cancers, and can themselves show altered expression in various tumor types. Here, we have investigated medulloblastoma tumors (MBs), which arise fro

Externí odkaz: https://doaj.org/article/17ac1e8186224d8390780dfd50d6c9ef

A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility

Autor: Antonio Varriale, Vincenzo Maione, Maria Frucci, Mariangela Vessichelli, Fabio Formiggini, Matteo Lo Monte, Angela Flagiello, Daniela Spano, Daniela Corda, Stefania Mariggiò, Piero Pucci, Alessia Varone, Sabato D'Auria, Carmen Valente, Clara Iannuzzi, Pompea Del Vecchio, Nadia Brancati, Lucia Banci, Alberto Luini, Manpreet Patheja

Publikováno v: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
Cell communication and signaling 17 (2019). doi:10.1186/s12964-019-0329-3
info:cnr-pdr/source/autori:Varone A., Mariggiò S., Patheja M., Maione V., Varriale A., Vessichelli M., Spano D., Formiggini F., Lo Monte M., Brancati N., Frucci M., Del Vecchio P., D'Auria S., Flagiello A., Iannuzzi C., Luini A., Pucci P., Banci L., Valente C., and Corda D./titolo:A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility/doi:10.1186%2Fs12964-019-0329-3/rivista:Cell communication and signaling/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:17

Background: Shp1, a tyrosine-phosphatase-1 containing the Src-homology 2 (SH2) domain, is involved in inflammatory and immune reactions, where it regulates diverse signalling pathways, usually by limiting cell responses through dephosphorylation of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ef9f3a2a55dfa9023818306b7ae338
http://link.springer.com/article/10.1186/s12964-019-0329-3

Spatio-Temporal Control of Dynamic Topographic Patterns on Azopolymers for Cell Culture Applications

Autor: Fabio Formiggini, Paolo A. Netti, Ravichandran H. Kollarigowda, Lucia Rossano, Silvia Cavalli, Maurizio Ventre, Carmela Rianna

Publikováno v: Advanced Functional Materials. 26:7572-7580

Cell response to exogenous cues is the result of a complex integration of multiple biochemical/biophysical signals, which might occur simultaneously and might be characterized by specific spatial and temporal patterns. Among these signals, surface to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5a5e2a415d75b19d6c0cd12789c7ad
https://doi.org/10.1002/adfm.201602577

A 14-3-3γ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIIIβ to regulate post-Golgi carrier formation

Autor: Renato Gaibisso, Stefania Spanò, Daniela Corda, Alessandro Pagliuso, Carmen Valente, Alberto Luini, Fabio Formiggini, Daniele Piccini, Gabriele Turacchio, Stefania Mariggiò, Giuseppe Di Tullio, Antonino Colanzi, Michele Santoro, Roman S. Polishchuk

Publikováno v: Nature Cell Biology
Nature Cell Biology; Vol 14
Nature cell biology (2012). doi:10.1038/ncb2445
info:cnr-pdr/source/autori:Valente C., Turacchio G., Mariggiò S., Pagliuso A., Gaibisso R., Di Tullio G., Santoro M., Formiggini F., Spanò S., Piccini D., Polishchuk R. S., Colanzi A., Luini A., Corda D./titolo:A 14-3-3? dimer-based scaffold bridges CtBP1-S%2FBARS to PI(4)KIII? to regulate post-Golgi carrier formation/doi:10.1038%2Fncb2445/rivista:Nature cell biology/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

Large pleiomorphic carriers leave the Golgi complex for the plasma membrane by en bloc extrusion of specialized tubular domains, which then undergo fission. Several components of the underlying molecular machinery have been identified, including thos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4834c7e91ad2c37e396b285b08b2a49b