Tumor microenvironment affects exogenous sodium/iodide symporter expression

Autor: Fabio Castillo-Rivera, Alejandro Ondo-Méndez, Julien Guglielmi, Jean-Marie Guigonis, Lun Jing, Sabine Lindenthal, Andrea Gonzalez, Diana López, Béatrice Cambien, Thierry Pourcher

Publikováno v: Translational Oncology, Vol 14, Iss 1, Pp 100937- (2021)

For decades, sodium/iodide symporter NIS-mediated iodide uptake has played a crucial role in the radioactive ablation of thyroid cancer cells. NIS-based gene therapy has also become a promising tool for the treatment of tumors of extrathyroidal origi

Externí odkaz: https://doaj.org/article/d5baa942ad04456ab8599c560d83ff6e

Tareas de un futuro inmediato (Tomado de La Universidad hacia el siglo XXI, 1995)

Autor: Fabio Castillo Figueroa

Publikováno v: La Universidad, Vol 9, Iss 28 (2017)

Fabio Castillo Figueroa fue un prestigioso académico y revolucionario, graduado de médico por la Universidad de El Salvador. Posteriormente estudió un doctorado en Fisiología en la Universidad de Pennsylvania. Siendo todavía estudiante de la Uni

Externí odkaz: https://doaj.org/article/379d9e268c684b0080e04829b56ad5fa

Hypoxia-inducible factor HIF-1α modulates drugs resistance in colon cancer cells

Autor: Lilia Del Riesgo, Alejandro Ondo, Yenith Cuellar, Luisa M. Matheus, Martha L. Pinzon-Daza, Fabio Castillo, Ruth Garzón

Publikováno v: Revista de la Facultad de Medicina, Volume: 66, Issue: 4, Pages: 543-550, Published: DEC 2018
Revista de la Facultad de Medicina, Vol 66, Iss 4, Pp 543-550 (2018)
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

Introduction: Drug resistance mechanisms may be associated with decreased cell death and its induction may depend on the response to oxidative stress caused by hypoxia. The correlation between hypoxia-inducible factor HIF-1α, the number of reactive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f187ffc97b101d5cd699b6e6682dfa
https://doi.org/10.15446/revfacmed.v66n4.55149

Xer Site Specific Recombination: Double and Single Recombinase Systems

Autor: Fabio Castillo, George Szatmari, Amal Benmohamed

Publikováno v: Frontiers in Microbiology

The separation and segregation of newly replicated bacterial chromosomes can be constrained by the formation of circular chromosome dimers caused by crossing over during homologous recombination events. In Escherichia coli and most bacteria, dimers a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957ea4a65f412335b7ae4fc92a7089ed

Identifying putativeMycobacterium tuberculosisRv2004c protein sequences that bind specifically to U937 macrophages and A549 epithelial cells

Autor: Manuel A. Patarroyo, Alvaro Puentes, Ricardo Vera, Hernando Curtidor, Jaiver E. Rosas, Manuel E. Patarroyo, Jimena Cortés, John Valbuena, Gloria Barrera, Marisol Ocampo, Fabio Castillo, Martha Forero, Luis E. Rodríguez, Rosalba Alfonso, Javier García

Publikováno v: Protein Science. 14:2767-2780

Virulence and immunity are still poorly understood in Mycobacterium tuberculosis. The H37Rv M. tuberculosis laboratory strain genome has been completely sequenced, and this along with proteomic technology represent powerful tools contributing toward

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9280cea68a33fc1d8260a533cdbc448
https://doi.org/10.1110/ps.051592505