Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Fabio Brocco"'
IGFBP7 activates retinoid acid–induced responses in acute myeloid leukemia stem and progenitor cells
Autor:
Linda Smit, Fabio Brocco, Eline Vermue, Han J. M. P. Verhagen, Noortje van Gils, Renee X. Menezes, Jeroen J. W. M. Janssen, Mei-Ling Tsui, Esmée Dekens, Fedor Denkers, Gert J. Ossenkoppele, Arjo Rutten, Floortje L. Kessler
Publikováno v:
Blood, 4(24), 6368-6383. American Society of Hematology
van Gils, N, Verhagen, H J M P, Rutten, A, Menezes, R X, Tsui, M-L, Vermue, E, Dekens, E, Brocco, F, Denkers, F, Kessler, F L, Ossenkoppele, G J, Janssen, J J W M & Smit, L 2020, ' IGFBP7 activates retinoid acid-induced responses in acute myeloid leukemia stem and progenitor cells ', Blood, vol. 4, no. 24, pp. 6368-6383 . https://doi.org/10.1182/bloodadvances.2020002812, https://doi.org/10.1182/BLOODADVANCES.2020002812
Blood Adv
van Gils, N, Verhagen, H J M P, Rutten, A, Menezes, R X, Tsui, M-L, Vermue, E, Dekens, E, Brocco, F, Denkers, F, Kessler, F L, Ossenkoppele, G J, Janssen, J J W M & Smit, L 2020, ' IGFBP7 activates retinoid acid-induced responses in acute myeloid leukemia stem and progenitor cells ', Blood, vol. 4, no. 24, pp. 6368-6383 . https://doi.org/10.1182/bloodadvances.2020002812, https://doi.org/10.1182/BLOODADVANCES.2020002812
Blood Adv
Treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA) in combination with low doses of arsenic trioxide or chemotherapy leads to exceptionally high cure rates (>90%). ATRA forces APL cells into differentiation and cell d
Autor:
Eline Vermue, Margaretha G. M. Roemer, Renee X. de Menezes, Fabio Brocco, Mei-Ling Tsui, Gert J. Ossenkoppele, Louise L.E. de Vos Klootwijk, Meyram Cil, Marjon A. Smit, Fedor Denkers, Han J.M.P. Verhagen, Sonja Zweegman, Stan Heukelom, Noortje van Gils, Arjo P Rutten, Anna van Rhenen, Linda Smit, Gerrit Jan Schuurhuis, Jeroen Janssen
Publikováno v:
Cancer Research, 78(13 Supplement), 1114-1114. American Association for Cancer Research Inc.
Cil, M, Vermue, E, Zweegman, S, Smit, M, Schuurhuis, G J, Klootwijk, L L D V, Menezes, R X, Tsui, M-L, Smit, L, Rutten, A, Gils, N V, Brocco, F, Roemer, M G, Ossenkoppele, G J, Verhagen, H J, Rhenen, A V, Janssen, J J, Denkers, F & Heukelom, S 2018, ' Abstract 1114: IGFBP7 reduces acute myeloid leukemia stem cell survival without affecting normal hematopoiesis ', Cancer Research, vol. 78, no. 13 Supplement, pp. 1114-1114 . https://doi.org/10.1158/1538-7445.am2018-1114
Cil, M, Vermue, E, Zweegman, S, Smit, M, Schuurhuis, G J, Klootwijk, L L D V, Menezes, R X, Tsui, M-L, Smit, L, Rutten, A, Gils, N V, Brocco, F, Roemer, M G, Ossenkoppele, G J, Verhagen, H J, Rhenen, A V, Janssen, J J, Denkers, F & Heukelom, S 2018, ' Abstract 1114: IGFBP7 reduces acute myeloid leukemia stem cell survival without affecting normal hematopoiesis ', Cancer Research, vol. 78, no. 13 Supplement, pp. 1114-1114 . https://doi.org/10.1158/1538-7445.am2018-1114
Only 30-40% of acute myeloid leukemia (AML) patients survive five years after diagnosis. This poor prognosis is mainly caused by treatment failure due to chemotherapy resistance and relapse. Leukemic stem cells (LSCs) are thought to be the major dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74fd79b27d4c2c4fcd78e51b85b1a9d
https://research.vumc.nl/en/publications/1814fe13-a507-41db-9ad8-11ca4feed46c
https://research.vumc.nl/en/publications/1814fe13-a507-41db-9ad8-11ca4feed46c
Autor:
Loredana Bruno, Fabio Brocco, Patrick Pauwels, Valentina Calò, Florinda Di Piazza, Viviana Bazan, Stefano Caruso, Antonio Russo, Marc Peeters, Marta Castiglia, Daniela Cabibi, Christian D. Rolfo, Francesco Passiglia, Konstantinos Papadimitriou
Publikováno v:
Cancer Research. 74:448-448
Introduction There are numerous causes triggering CRC. 25-80% of CRC shown a deregulation in Epidermal Growth Factor Receptor (EGFR) pathway. Two signaling pathways downstream of the EGFR are dysregulated in CRC the mitogen-activated protein kinase (