Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fabio Annunziata"'
Autor:
Nunzia Pastore, Keith Blomenkamp, Fabio Annunziata, Pasquale Piccolo, Pratibha Mithbaokar, Rosa Maria Sepe, Francesco Vetrini, Donna Palmer, Philip Ng, Elena Polishchuk, Simona Iacobacci, Roman Polishchuk, Jeffrey Teckman, Andrea Ballabio, Nicola Brunetti‐Pierri
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 3, Pp 397-412 (2013)
Abstract Alpha‐1‐anti‐trypsin deficiency is the most common genetic cause of liver disease in children and liver transplantation is currently the only available treatment. Enhancement of liver autophagy increases degradation of mutant, hepatoto
Externí odkaz:
https://doaj.org/article/f439b5daf4144d6699e801b90df4847d
Autor:
Antoni Matyjaszkiewicz, Mario di Bernardo, Claire S. Grierson, Nigel J. Savery, Lucia Marucci, Fabio Annunziata, Gianfranco Fiore
Publikováno v:
Matyjaszkiewicz, A W, Fiore, G, Annunziata, F, Grierson, C S, Savery, N J, Marucci, L & di Bernardo, M 2017, ' BSim 2.0 : An Advanced Agent-Based Cell Simulator ', ACS Synthetic Biology, vol. 6, no. 10, pp. 1969-1972 . https://doi.org/10.1021/acssynbio.7b00121
Agent-based models (ABMs) provide a number of advantages relative to traditional continuum modeling approaches, permitting incorporation of great detail and realism into simulations, allowing in silico tracking of single-cell behaviors and correlatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8bb8ed58b38ed9776e51dd9e45343b
https://doi.org/10.1021/acssynbio.7b00121
https://doi.org/10.1021/acssynbio.7b00121
Autor:
Nigel J. Savery, Antoni Matyjaszkiewicz, Claire S. Grierson, Lucia Marucci, Gianfranco Fiore, Fabio Annunziata, Mario di Bernardo
Publikováno v:
Annunziata, F, Matyjaszkiewicz, A, Fiore, G, Grierson, C, Di Bernardo, M, Marucci, L & Savery, N 2017, ' An Orthogonal Multi-input Integration System to Control Gene Expression in Escherichia coli ', ACS Synthetic Biology, vol. 6, no. 10, pp. 1816-1824 . https://doi.org/10.1021/acssynbio.7b00109
In many biotechnological applications, it is useful for gene expression to be regulated by multiple signals, as this allows the programming of complex behavior. Here we implement, in Escherichia coli, a system that compares the concentration of two s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987e8c8a64c5557ffac551cbe2a75667
https://pubmed.ncbi.nlm.nih.gov/28723080
https://pubmed.ncbi.nlm.nih.gov/28723080
Autor:
Lucia Marucci, Fabio Annunziata, Gianfranco Fiore, Claire S. Grierson, Mario di Bernardo, Antoni Matyjaszkiewicz, Nigel J. Savery
Publikováno v:
Fiore, G, Matyjaszkiewicz, A, Annunziata, F, Grierson, C, Savery, N J, Marucci, L & Di Bernardo, M 2017, Design of a multicellular feedback control strategy in a synthetic bacterial consortium . in 2016 IEEE 55th Conference on Decision and Control (CDC 2016) : Proceedings of a meeting held 12-14 December 2016, Las Vegas, Nevada, USA ., 7798771, Institute of Electrical and Electronics Engineers (IEEE), pp. 3338-3343, 55th IEEE Conference on Decision and Control, CDC 2016, Las Vegas, United States, 12/12/16 . https://doi.org/10.1109/CDC.2016.7798771
CDC
CDC
Living organisms employ endogenous negative feedback loops to maintain homeostasis despite environmental fluctuations. An intriguing challenge in Synthetic Biology is that of designing and implementing synthetic circuits to control host cells' behavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478a8371e3e2780a70647dc1a3d87ec3
http://www.scopus.com/inward/record.url?scp=85010801618&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85010801618&partnerID=8YFLogxK
Autor:
Fabio Annunziata, Mario di Bernardo, Gianfranco Fiore, Antoni Matyjaszkiewicz, Lucia Marucci, Claire S. Grierson, Nigel J. Savery
Publikováno v:
Fiore, G, Matyjaszkiewicz, A, Annunziata, F, Grierson, C, Savery, N, Marucci, L & Di Bernardo, M 2017, ' In-Silico Analysis and Implementation of a Multicellular Feedback Control Strategy in a Synthetic Bacterial Consortium ', ACS Synthetic Biology, vol. 6, no. 3, pp. 507–517 . https://doi.org/10.1021/acssynbio.6b00220
Living organisms employ endogenous negative feedback loops to maintain homeostasis despite environmental fluctuations. A pressing open challenge in Synthetic Biology is to design and implement synthetic circuits to control host cells' behavior, in or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de83202534d4c2a2100e38034063b983
https://research-information.bris.ac.uk/en/publications/dc58951f-c31d-42a3-85e8-6e548a819278
https://research-information.bris.ac.uk/en/publications/dc58951f-c31d-42a3-85e8-6e548a819278
Autor:
Roman S. Polishchuk, Erin J. Feeney, Hossein Zare, Lishu Li, Carmine Spampanato, Monica Cardone, Fabio Annunziata, Giancarlo Parenti, Rosa Puertollano, Jeong-A Lim, Andrea Ballabio, Nina Raben
Publikováno v:
EMBO Molecular Medicine
A recently proposed therapeutic approach for lysosomal storage disorders (LSDs) relies upon the ability of transcription factor EB (TFEB) to stimulate autophagy and induce lysosomal exocytosis leading to cellular clearance. This approach is particula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48b84e4d50ab04e5b1ae24f9082caae
http://europepmc.org/articles/PMC3662313
http://europepmc.org/articles/PMC3662313
Autor:
Philip Ng, Elena Polishchuk, Nicola Brunetti-Pierri, Simona Iacobacci, Andrea Ballabio, Rosa Maria Sepe, Donna Palmer, Roman S. Polishchuk, Keith Blomenkamp, Nunzia Pastore, Fabio Annunziata, Jeffrey Teckman, Francesco Vetrini, Pasquale Piccolo, Pratibha Mithbaokar
Publikováno v:
EMBO Molecular Medicine
Alpha-1-anti-trypsin deficiency is the most common genetic cause of liver disease in children and liver transplantation is currently the only available treatment. Enhancement of liver autophagy increases degradation of mutant, hepatotoxic alpha-1-ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66ad9f5c1e7d5000459125a7ce9b732
https://doi.org/10.1002/emmm.201202046
https://doi.org/10.1002/emmm.201202046
Autor:
Roman S. Polishchuk, Kai Simons, Alessia Lombardi, Nicolina Cristina Sorrentino, Alessandro Fraldi, Anthony O. Fedele, Diego L. Medina, Fabio Annunziata, Hermann-Josef Kaiser, Andrea Ballabio, Carmine Spampanato
Publikováno v:
EMBO J
Partial Retraction of: The EMBO Journal (2010) 29: 3607-3620. DOI: 10.1038/emboj.2010.237 | Published online 24 September 2010 Journal statement The journal contacted the authors in February 2022 about potential image insertions and duplications in F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0592aa5e1cb14a701c3d1cc3e90321b
https://doi.org/10.1038/emboj.2010.237
https://doi.org/10.1038/emboj.2010.237
Autor:
Lucia Marucci, Mario di Bernardo, Claire S. Grierson, Antoni Matyjaszkiewicz, Gianfranco Fiore, Fabio Annunziata, Nigel J. Savery
Publikováno v:
New Biotechnology. 33:S184-S185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda5f675d6fbdccde98992476480233a
https://doi.org/10.1016/j.nbt.2016.06.1360
https://doi.org/10.1016/j.nbt.2016.06.1360
Autor:
Alessia Lombardi, Andrea Ballabio, Roberto Sitia, Carmine Spampanato, Fabio Annunziata, Ester Zito, Marianna Cozzolino, Maria Pia Cosma, Maria Chiara Monti, Piero Pucci, Alessandro Fraldi
Sulfatase modifying factor 1 (SUMF1) encodes for the formylglicine generating enzyme, which activates sulfatases by modifying a key cysteine residue within their catalytic domains. SUMF1 is mutated in patients affected by multiple sulfatase deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99f2c6ffad9c8a26c91912a48d2b668