Small intestine remodeling in male Goto–Kakizaki rats

Autor: Joice Naiara Bertaglia Pereira, Gilson Masahiro Murata, Fabio Takeo Sato, Aline Rosa Marosti, Carla Roberta de Oliveira Carvalho, Rui Curi

Publikováno v: Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)

Abstract Background Obesity is associated with the development of insulin resistance (IR) and type‐2 diabetes mellitus (T2DM); however, not all patients with T2DM are obese. The Goto–Kakizaki (GK) rat is an experimental model of spontaneous and n

Externí odkaz: https://doaj.org/article/97b4783806b84c38b1cf4d06e55aa68d

Tributyrin Attenuates Metabolic and Inflammatory Changes Associated with Obesity through a GPR109A-Dependent Mechanism

Autor: Fabio Takeo Sato, Yu Anne Yap, Amanda Rabello Crisma, Mariana Portovedo, Gilson Masahiro Murata, Sandro Massao Hirabara, Willian Rodrigues Ribeiro, Caroline Marcantonio Ferreira, Maysa Mariana Cruz, Joice Naiara Bertaglia Pereira, Tanyara Baliani Payolla, Suzana Eiko Sato Guima, Andrew Maltez Thomas, João Carlos Setubal, Maria Isabel Cardoso Alonso-Vale, Marinilce Fagundes Santos, Rui Curi, Eliana Marino, Marco A. R. Vinolo

Publikováno v: Cells, Vol 9, Iss 9, p 2007 (2020)

Obesity is linked with altered microbial short-chain fatty acids (SCFAs), which are a signature of gut dysbiosis and inflammation. In the present study, we investigated whether tributyrin, a prodrug of the SCFA butyrate, could improve metabolic and i

Externí odkaz: https://doaj.org/article/951345acd32f4b8292d95047e44f900b

Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats.

Autor: Hosana G Rodrigues, Marco A R Vinolo, Fabio T Sato, Juliana Magdalon, Carolina M C Kuhl, Ana S Yamagata, Ana Flávia M Pessoa, Gabriella Malheiros, Marinilce F Dos Santos, Camila Lima, Sandra H Farsky, Niels O S Camara, Maria R Williner, Claudio A Bernal, Philip C Calder, Rui Curi

Publikováno v: PLoS ONE, Vol 11, Iss 10, p e0165115 (2016)

Impaired wound healing has been widely reported in diabetes. Linoleic acid (LA) accelerates the skin wound healing process in non-diabetic rats. However, LA has not been tested in diabetic animals.We investigated whether oral administration of pure L

Externí odkaz: https://doaj.org/article/81988f370c1b4083be74be150f76cedb

Long-term increase of insulin secretion in mice subjected to pregnancy and lactation

Autor: Silvana Bordin, Everardo M. Carneiro, Fabio Takeo Sato, Caio Jordão Teixeira, Jean Franciesco Vettorazzi, Gabriel Forato Anhê, Fabiola Sales Furtuoso, Isabel Gouveia Adabo, Julia Modesto Vicente, Junia Carolina Santos-Silva, Dailson Nogueira de Souza, Marco Aurélio Ramirez Vinolo

Publikováno v: Endocrine Connections
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Endocrine Connections, Vol 9, Iss 4, Pp 299-308 (2020)

Purpose Observational studies show that longer breastfeeding periods reduce maternal risk of type 2 diabetes mellitus. However, it is currently unknown if the long-term benefits of breastfeeding for maternal glucose homeostasis are linked to changes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50dc30c729113981c18d2443fef0668
http://europepmc.org/articles/PMC7159261

As bases neurobiológicas do transtorno obsessivo-compulsivo e da síndrome de Tourette The neurobiological bases of obsessive-compulsive disorder and Tourette syndrome

Autor: Marcos T. Mercadante, Maria C. Rosario-Campos, Lucas C. Quarantini, Fabio P. Sato

Publikováno v: Jornal de Pediatria, Vol 80, Iss 2, Pp 35-44 (2004)

OBJETIVO: Revisar as teorias e evidências das bases neurobiológicas do transtorno obsessivo-compulsivo e da síndrome de Tourette. FONTES DOS DADOS: Revisão dos estudos que investigam a neuroanatomia, neuroimagem, genética e imunologia desses tra

Externí odkaz: https://doaj.org/article/574b9c346f6d43668911d1579fc8ed04