Výsledky vyhledávání - "Fabio A Digirolamo"

Akademický článek

A Preventive Cytokine Treatment of the Viral Infectious Bursal Disease (IBD) of Chickens

Autor: Rosana Mattiello, Elisa D’Ambrosio, Maximiliano Wilda, Melisa Sayé, Mariana R. Miranda, Pablo Maure, Claudio A. Pereira, Fabio A. Digirolamo

Publikováno v: The Journal of Poultry Science, Vol 52, Iss 2, Pp 145-150 (2015)

Infectious bursal disease (IBD) is a viral disease of young chickens that produce severe lesions in the bursa of Fabricius and other organs inducing immunosuppression and mortality in birds. This study indicates that oral administration of IFN-α and

Externí odkaz: https://doaj.org/article/d64bba4a45684adca1e3f543ed9df65b

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Trypanocidal activity of the anthocyanidin delphinidin, a non-competitive inhibitor of arginine kinase

Autor: Claudio A. Pereira, Chantal Reigada, Fabio A Digirolamo, Edward A. Valera-Vera, Facundo Galceran, Melisa Sayé, Mariana R. Miranda

Publikováno v: Natural Product Research. 36:3153-3157

The enzyme arginine kinase from Trypanosoma cruzi (TcAK) catalyzes the interconversion of arginine and phosphoarginine to maintain the ATP/ADP cell balance, and is involved in the parasites energetic homeostasis and stress responses. Using virtual sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23397a7a9ec3be86963562cbcdcf406d
https://doi.org/10.1080/14786419.2021.1947270

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Revisiting trypanosomatid nucleoside diphosphate kinases

Autor: Mariana R Miranda, Melisa Sayé, Chantal Reigada, Facundo Galceran, Marcos Rengifo, Belen J Maciel, Fabio A Digirolamo, Claudio A Pereira

Publikováno v: Memórias do Instituto Oswaldo Cruz. 116

An increasing amount of research has led to the positioning of nucleoside diphosphate kinases (NDPK/NDK) as key metabolic enzymes among all organisms. They contribute to the maintenance the intracellular di- and tri- phosphate nucleoside homeostasis,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab98b220af2f72eb6206698ea8883ce
https://doi.org/10.1590/0074-02760210339

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IgE antibodies against Trypanosoma cruzi arginine kinase in patients with chronic Chagas disease

Autor: Vilma G. Duschak, Mariana R. Miranda, Fabio A Digirolamo, Juan Luis Concepción, Yolanda Hernández, Luciana Lía Soprano, Gonzalo Raúl Acevedo, Ana J. Cáceres, Karina A. Gómez, Edward A. Valera-Vera, Claudio A. Pereira, Marisa M. Fernández

Publikováno v: Molecular immunology. 138

Arginine kinase (AK) is an enzyme present in various invertebrates, as well as in some trypanosomatids such as T. cruzi, the etiological agent that causes Chagas disease. In invertebrates, this protein acts as an allergen inducing an IgE-type humoral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1f6ab64e976fe8a3e91c15f47699da
https://pubmed.ncbi.nlm.nih.gov/34364074

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Effect of capsaicin on the protozoan parasite Trypanosoma cruzi

Autor: Claudio A. Pereira, Fabio A Digirolamo, Facundo Galceran, Melisa Sayé, Edward A. Valera-Vera, Chantal Reigada, Mariana R. Miranda

Publikováno v: FEMS Microbiology Letters. 367

Trypanosoma cruzi is the causative agent of Chagas disease. There are only two approved treatments, both of them unsuitable for the chronic phase, therefore the development of new drugs is a priority. Trypanosoma cruzi arginine kinase (TcAK) is a pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dc5e640e5720ccd5f08ff6c919ca15
https://doi.org/10.1093/femsle/fnaa194

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Capsaicin inhibits arginine kinase and exerts anti-Trypanosoma cruzi activity

Autor: Melisa Sayé, Claudio A. Pereira, Fabio A Digirolamo, Mariana R. Miranda, Edward A. Valera-Vera, Chantal Reigada

Trypanosoma cruzi is the causative agent of Chagas disease, considered within the list of twenty neglected diseases according to the World Health Organization. There are only two therapeutic drugs for Chagas disease, both of them unsuitable for the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ffc466b0187dacedd883b7614fe0c8c
https://doi.org/10.1101/2020.06.23.167346

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A novel stage-specific glycosomal nucleoside diphosphate kinase from Trypanosoma cruzi

Autor: León A. Bouvier, Claudio A. Pereira, Chantal Reigada, Fabio A Digirolamo, María de los Milagros Camara, Melisa Sayé

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Nucleoside diphosphate kinases (NDPK) are key enzymes involved in the intracellular nucleotide maintenance in all living organisms, especially in trypanosomatids which are unable to synthesise purines de novo. Four putative NDPK isoforms were identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b210573ac6c86d4254cd32b1d9230c
https://folia.paru.cas.cz/artkey/fol-201701-0006_a_novel_stage-specific_glycosomal_nucleoside_diphosphate_kinase_from_trypanosoma_cruzi.php

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Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure

Autor: Claudio A. Pereira, Fabio A Digirolamo, Chantal Reigada, Mariana R. Miranda, Melisa Sayé

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Nucleoside diphosphate kinase (NDPK) is a key enzyme in the control of cellular concentrations of nucleoside triphosphates, and has been shown to play important roles in many cellular processes. In this work we investigated the subcellular localizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c519e827c7c422752740fb1103c982a1
https://doi.org/10.1016/j.exppara.2014.04.009

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