Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Fabio, Zuccotto"'
Autor:
Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K. Tamaki, Kirsteen I. Buchanan, John Post, Karen Dowers, Sharon M. Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H. Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C. Kim, James M. Bean, Navid Nahiyaan, Kyu Y. Rhee, Qinglan Wang, Vee Y. Tan, Helena I. M. Boshoff, Paul J. Converse, Si-Yang Li, Yong S. Chang, Nader Fotouhi, Anna M. Upton, Eric L. Nuermberger, Dirk Schnappinger, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Paul G. Wyatt, Laura A. T. Cleghorn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Tuberculosis is a major cause of mortality, and the rise of drug-resistant strains of Mycobacterium tuberculosis requires the urgent development of safe and effective treatments. In this work, the authors develop a compound against lysyl-tRNA synthet
Externí odkaz:
https://doaj.org/article/3aefb9dc25794e5b8cda7dfd998654ed
Autor:
Peter C. Ray, Margaret Huggett, Penelope A. Turner, Malcolm Taylor, Laura A. T. Cleghorn, Julie Early, Anuradha Kumar, Shilah A. Bonnett, Lindsay Flint, Douglas Joerss, James Johnson, Aaron Korkegian, Steven Mullen, Abraham L. Moure, Susan H. Davis, Dinakaran Murugesan, Michael Mathieson, Nicola Caldwell, Curtis A. Engelhart, Dirk Schnappinger, Ola Epemolu, Fabio Zuccotto, Jennifer Riley, Paul Scullion, Laste Stojanovski, Lisa Massoudi, Gregory T. Robertson, Anne J. Lenaerts, Gail Freiberg, Dale J. Kempf, Thierry Masquelin, Philip A. Hipskind, Joshua Odingo, Kevin D. Read, Simon R. Green, Paul G. Wyatt, Tanya Parish
Publikováno v:
ACS Omega, Vol 6, Iss 3, Pp 2284-2311 (2021)
Externí odkaz:
https://doaj.org/article/0a27546e2eeb4807bfe33c85491f6518
Publikováno v:
ACS Omega. 8:15083-15098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3828b6af71e58964fed8b5e1fc1d1d4f
https://doi.org/10.1021/acsomega.2c08132
https://doi.org/10.1021/acsomega.2c08132
Autor:
James S. Martin, Claire J. Mackenzie, De Lin, Nadine Homeyer, David W. Gray, Fabio Zuccotto, Ian H. Gilbert
Publikováno v:
ACS Omega. 8:12787-12804
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce02eeb04ff7b9d23bcab7c2b09d305
https://doi.org/10.1021/acsomega.2c08031
https://doi.org/10.1021/acsomega.2c08031
Autor:
Juan F Quintana, Juan Bueren-Calabuig, Fabio Zuccotto, Harry P de Koning, David Horn, Mark C Field
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008458 (2020)
Defining mode of action is vital for both developing new drugs and predicting potential resistance mechanisms. Sensitivity of African trypanosomes to pentamidine and melarsoprol is predominantly mediated by aquaglyceroporin 2 (TbAQP2), a channel asso
Externí odkaz:
https://doaj.org/article/f3985bc0ed7a43708934feb0f30f6f83
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217828 (2019)
The discovery of 20 unconventional kinetochore proteins in Trypanosoma brucei has opened a new and interesting area of evolutionary research to study a biological process previously thought to be highly conserved in all eukaryotes. In addition, the d
Externí odkaz:
https://doaj.org/article/10a149edc2654e08b646177273df4903
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Supplementary Figure S2 - PDF file 456K, Time-lapse imaging of A375 cells treated with NMS-E973
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f283c674905df024deea1ce236ca7aa
https://doi.org/10.1158/1078-0432.22451829.v1
https://doi.org/10.1158/1078-0432.22451829.v1
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Supplementary Table S1 - PDF file 94K, Antiproliferative activity of NMS-E973
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d89fb90cbe5dad008cd241246f1ef48
https://doi.org/10.1158/1078-0432.22451817.v1
https://doi.org/10.1158/1078-0432.22451817.v1
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Purpose: Recent developments of second generation Hsp90 inhibitors suggested a potential for development of this class of molecules also in tumors that have become resistant to molecular targeted agents. Disease progression is often due to brain meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0947fcab05687d15962c1dd2f2c4d7a7
https://doi.org/10.1158/1078-0432.c.6522303.v1
https://doi.org/10.1158/1078-0432.c.6522303.v1
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Supplementary Methods - PDF file 56K, Time-lapse imaging of A375 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890811bb8dc8943c26d3ed639f1dc414
https://doi.org/10.1158/1078-0432.22451820
https://doi.org/10.1158/1078-0432.22451820