Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Fabio, Santoro"'
SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation
Autor:
Zivojin Jevtic, Vittoria Matafora, Francesca Casagrande, Fabio Santoro, Saverio Minucci, Massimilliano Garre’, Milad Rasouli, Olaf Heidenreich, Giovanna Musco, Jürg Schwaller, Angela Bachi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Acute myeloid leukemia (AML) is characterized by accumulation of aberrantly differentiated hematopoietic myeloid progenitor cells. The karyotyping-silent NUP98-NSD1 fusion is a molecular hallmark of pediatric AML and is associated
Externí odkaz:
https://doaj.org/article/de8b70eb51e347ddba8b9d02fc7d69e4
Autor:
Elena Ceccacci, Emanuela Villa, Fabio Santoro, Saverio Minucci, Christiana Ruhrberg, Alessandro Fantin
Publikováno v:
Journal of Developmental Biology, Vol 11, Iss 2, p 15 (2023)
During prenatal life, the foetal liver is colonised by several waves of haematopoietic progenitors to act as the main haematopoietic organ. Single cell (sc) RNA-seq has been used to identify foetal liver cell types via their transcriptomic signature
Externí odkaz:
https://doaj.org/article/99f3cf3dd2824fc58e6b0cef3105543c
Autor:
Simona Moretti, Amal Kamal Abdel-Aziz, Elena Ceccacci, Isabella Pallavicini, Fabio Santoro, Hugues de Thé, Saverio Minucci
Publikováno v:
Leukemia. 36:1306-1312
According to a hierarchical model, targeting leukemia-initiating cells (LICs) was speculated to achieve complete remission (CR) or cure. Nonetheless, increasing evidence emphasized the plasticity of differentiated blasts undergoing interconversion in
Autor:
Brucato, Alberto, Caputo, Giuseppe, Grisafi, Franco, Scargiali, Francesca, Gianluca Minelli, Gaetano Tuzzolino, Calogero Gattuso, Roberto Rizzo, Marialaura Alessi, Fabio Santoro
Described herein is a reactor (1) includes: a first reaction volume (V1), a second reaction volume (V2), wherein: the first reaction volume (V1) is in fluid communication with an inlet port for an oxidizer agent (OX_IN), an inlet port for at least on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::b8f70e21822d2a10caf27723284367a1
https://hdl.handle.net/10447/588993
https://hdl.handle.net/10447/588993
Autor:
Glòria Mas, Fabio Santoro, Enrique Blanco, Gianni Paolo Gamarra Figueroa, François Le Dily, Gianmaria Frigè, Enrique Vidal, Francesca Mugianesi, Cecilia Ballaré, Arantxa Gutierrez, Aleksandra Sparavier, Marc A. Marti-Renom, Saverio Minucci, Luciano Di Croce
Publikováno v:
Genes & Dev
Genome organization plays a pivotal role in transcription, but how transcription factors (TFs) rewire the structure of the genome to initiate and maintain the programs that lead to oncogenic transformation remains poorly understood. Acute promyelocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3103e2f22d1ac61ebb6216e89023f71d
http://hdl.handle.net/10230/53063
http://hdl.handle.net/10230/53063
Autor:
Glòria, Mas, Fabio, Santoro, Enrique, Blanco, Gianni Paolo, Gamarra Figueroa, François, Le Dily, Gianmaria, Frigè, Enrique, Vidal, Francesca, Mugianesi, Cecilia, Ballaré, Arantxa, Gutierrez, Aleksandra, Sparavier, Marc A, Marti-Renom, Saverio, Minucci, Luciano, Di Croce
Publikováno v:
Genesdevelopment. 36(7-8)
Genome organization plays a pivotal role in transcription, but how transcription factors (TFs) rewire the structure of the genome to initiate and maintain the programs that lead to oncogenic transformation remains poorly understood. Acute promyelocyt
Autor:
Ilaria Schiavoni, Saverio Minucci, Bruno Achutti Duso, Isabella Pallavicini, Emanuele Bonetti, Elena Gaviln, Mauro Romanenghi, Rani Pallavi, Gianluca Fossati, Giuseppe Meroni, Giorgio Fedele, Pier Giuseppe Pelicci, Luca Mazzarella, Fabio Santoro, Sebastiano Pasqualato, Paola Stefanelli, Roberto Ravasio, Deborah Trastulli, Gabriele Buttinelli, Angela Di Martino, Tommaso Leonardi, Paul Edward Massa, Christian Steinkühler, Simona Rodighiero, Claudia Gentile
Tissue-resident macrophages exert critical but conflicting effects on the progression of coronavirus infections by secreting both anti-viral type I Interferons and tissue-damaging inflammatory cytokines. Steroids, the only class of host-targeting dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d1887ee346a84e090fc401fe4be292
https://doi.org/10.1101/2021.05.02.441948
https://doi.org/10.1101/2021.05.02.441948
Autor:
Fabio Santoro, Oreste Maria Petrillo
A Legal Thriller about two lawyers working on opposite sides of the Channel, whose destinies are fatally intertwined. A pharmaceutical patent worth billions, a brutally murdered man and a trial that appears impossible to win. These are the facts at t
Autor:
Fabio Santoro, Oreste Maria Petrillo
Юридический триллер о двух адвокатах, которые работают на противоположных берегах Ла-Манша и судьбы которых пересекаются в смертельной
Autor:
Christopher R. Vakoc, Colin M. House, Eva Vidacs, Parinaz Mehdipour, Katrina J. Falkenberg, Eric Wang, Geoffrey M. Matthews, Leonie A. Cluse, Ricky W. Johnstone, James R. Rusche, Fabio Santoro, Johannes Zuber, Mareike Roth, Kym Stanley, Saverio Minucci
Publikováno v:
Blood. 126:2392-2403
Histone deacetylase (HDAC) inhibitors (HDACis) have demonstrated activity in hematological and solid malignancies. Vorinostat, romidepsin, belinostat, and panobinostat are Food and Drug Administration-approved for hematological malignancies and inhib