Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Fabio, Romerio"'
Autor:
Angelo Pavesi, Fabio Romerio
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTDespite being first identified more than three decades ago, the antisense gene asp of HIV-1 remains an enigma. asp is present uniquely in pandemic (group M) HIV-1 strains, and it is absent in all non-pandemic (out-of-M) HIV-1 strains and virt
Externí odkaz:
https://doaj.org/article/ea66f4ae852e4a19800c2f6e94eebef4
Autor:
Fabio Romerio
Publikováno v:
Retrovirology, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Most proteins expressed by endogenous and exogenous retroviruses are encoded in the sense (positive) strand of the genome and are under the control of regulatory elements within the 5’ long terminal repeat (LTR). A number of retroviral gen
Externí odkaz:
https://doaj.org/article/794baa8c20c04265b12a1be22a5295e2
Autor:
Matthew Weichseldorfer, Yvonne Affram, Alonso Heredia, Zahra Rikhtegaran-Tehrani, Mohammad M. Sajadi, Sumiko P. Williams, Yutaka Tagaya, Francesca Benedetti, Habib O. Ramadhani, Frank Denaro, Arshi Munawwar, Joseph Bryant, Davide Zella, Marvin Reitz, Fabio Romerio, Olga S. Latinovic
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract HIV-1 reservoirs persist in the presence of combined antiretroviral therapy (cART). However, cART has transformed HIV-1 infection into a chronic disease marked by control of HIV-1 viral load and mortality reduction. Major challenges remain,
Externí odkaz:
https://doaj.org/article/6527c26b880c42f399bb579aa07db0c0
Autor:
Angelo Pavesi, Fabio Romerio
Publikováno v:
Viruses, Vol 15, Iss 7, p 1580 (2023)
A common feature of the mammalian Lentiviruses (family Retroviridae) is an RNA genome that contains an extremely high frequency of adenine (31.7–38.2%) while being extremely poor in cytosine (13.9–21.2%). Such a biased nucleotide composition has
Externí odkaz:
https://doaj.org/article/270696a7c4bc4fcd92e0d1a834d2ce19
Publikováno v:
Non-Coding RNA, Vol 9, Iss 1, p 5 (2023)
Nucleosomes positioned on the HIV-1 5′ long terminal repeat (LTR) regulate sense transcription as well as the establishment and maintenance of latency. A negative-sense promoter (NSP) in the 3′ LTR expresses antisense transcripts with coding and
Externí odkaz:
https://doaj.org/article/9d0d0ae31abd4dc88aee33a87fb4f5d6
Autor:
Angelo Pavesi, Fabio Romerio
Publikováno v:
Viruses, Vol 14, Iss 1, p 146 (2022)
Gene overprinting occurs when point mutations within a genomic region with an existing coding sequence create a new one in another reading frame. This process is quite frequent in viral genomes either to maximize the amount of information that they e
Externí odkaz:
https://doaj.org/article/a7fd6cd97b45442ab9bec4ac83b355a4
Publikováno v:
Vaccines, Vol 9, Iss 5, p 513 (2021)
Viruses have developed incredibly creative ways of making a virtue out of necessity, including taking full advantage of their small genomes. Indeed, viruses often encode multiple proteins within the same genomic region by using two or more reading fr
Externí odkaz:
https://doaj.org/article/d993ba3355ba4158a4f40696d9b37340
Publikováno v:
Viruses, Vol 13, Iss 5, p 795 (2021)
Natural antisense transcripts (NATs) represent a class of RNA molecules that are transcribed from the opposite strand of a protein-coding gene, and that have the ability to regulate the expression of their cognate protein-coding gene via multiple mec
Externí odkaz:
https://doaj.org/article/506484c7640042b6bf74fdbcd2459ef5
Autor:
Mariana Estevez, Rui Li, Biplab Paul, Kaveh Daneshvar, Alan C. Mullen, Fabio Romerio, Balasubrahmanyam Addepalli
Publikováno v:
RNA. 28:697-710
The human immunodeficiency virus type 1 (HIV-1) encodes multiple RNA molecules. Transcripts that originate from the proviral 5′ long terminal repeat (LTR) function as messenger RNAs for the expression of 16 different mature viral proteins. In addit
Autor:
Gavin C. Sampey, Sergey Iordanskiy, Michelle L. Pleet, Catherine DeMarino, Fabio Romerio, Renaud Mahieux, Fatah Kashanchi
Publikováno v:
Viruses, Vol 12, Iss 10, p 1067 (2020)
Human immunodeficiency virus 1 (HIV-1) is the most prevalent human retrovirus. Recent data show that 34 million people are living with HIV-1 worldwide. HIV-1 infections can lead to AIDS which still causes nearly 20,000 deaths annually in the USA alon
Externí odkaz:
https://doaj.org/article/d929319136b64e188d46ab8bc45c16ba