Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Fabio, Pittella Silva"'
Autor:
Claudia C. Gatto, Cássia de Q. O. Cavalcante, Francielle C. Lima, Érica C. M. Nascimento, João B. L. Martins, Brunna L. O. Santana, Ana C. M. Gualberto, Fabio Pittella-Silva
Publikováno v:
Molecules, Vol 29, Iss 12, p 2759 (2024)
The current article reports the investigation of three new Ni(II) complexes with ONS-donor dithiocarbazate ligands: [Ni(L1)PPh3] (1), [Ni(L2)PPh3] (2), and [Ni(L2)Py] (3). Single-crystal X-ray analyses revealed mononuclear complexes with a distorted
Externí odkaz:
https://doaj.org/article/ca63981e1910438f9a7b45a9ef9c2df9
Autor:
Alan Jhones Barbosa Assis, Brunna Letícia de Oliveira Santana, Ana Cristina Moura Gualberto, Fabio Pittella-Silva
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Acute Lymphoblastic Leukemia (ALL) is the predominant hematological malignancy in pediatric populations, originating from B- or T-cell precursors within the bone marrow. The disease exhibits a high degree of heterogeneity, both at the molecular level
Externí odkaz:
https://doaj.org/article/75e5be9540044ffbb3b9c067e18f0553
Autor:
Cássia de Q. O. Cavalcante, Tales H. A. da Mota, Diêgo M. de Oliveira, Érica C. M. Nascimento, João B. L. Martins, Fabio Pittella-Silva, Claudia C. Gatto
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
In the search for new metal complexes with antitumor potential, two dithiocarbazate ligands derived from 1,1,1-trifluoro-2,4-pentanedione (H2L1) and (H2L2) and four Ni(II) complexes, [Ni(L1)PPh3] (1), [Ni(L1)Py] (2), [Ni(L2)PPh3] (3), and [Ni(L2)Py]
Externí odkaz:
https://doaj.org/article/beacccfcadd54069b775edbb33e99a4b
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/710430c85b2c483eb54103549e9dd2c0
Autor:
Doralina do Amaral Rabello, Vivian D’Afonseca da Silva Ferreira, Maria Gabriela Berzoti-Coelho, Sandra Mara Burin, Cíntia Leticia Magro, Maira da Costa Cacemiro, Belinda Pinto Simões, Felipe Saldanha-Araujo, Fabíola Attié de Castro, Fabio Pittella-Silva
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm whose pathogenesis is linked to the Philadelphia chromosome presence that generates the BCR–ABL1 fusion oncogene. Tyrosine kinase inhibitors (TKI) such as im
Externí odkaz:
https://doaj.org/article/a40b924a4a214115a250fe3a8a6535b5
Autor:
Shi Chen, Rafal P Wiewiora, Fanwang Meng, Nicolas Babault, Anqi Ma, Wenyu Yu, Kun Qian, Hao Hu, Hua Zou, Junyi Wang, Shijie Fan, Gil Blum, Fabio Pittella-Silva, Kyle A Beauchamp, Wolfram Tempel, Hualiang Jiang, Kaixian Chen, Robert J Skene, Yujun George Zheng, Peter J Brown, Jian Jin, Cheng Luo, John D Chodera, Minkui Luo
Publikováno v:
eLife, Vol 8 (2019)
Elucidating the conformational heterogeneity of proteins is essential for understanding protein function and developing exogenous ligands. With the rapid development of experimental and computational methods, it is of great interest to integrate thes
Externí odkaz:
https://doaj.org/article/a6d43dbd70b84f88920fbdbf903ea4a3
Autor:
Yoichi Furukawa, Yusuke Nakamura, Masabumi Shibuya, Takeshi Nagayasu, Kiyoshi Yamaguchi, Fabio Pittella Silva, Ryuji Hamamoto, Masaki Kunizaki
Supplementary Figure Legends 1-2 from The Lysine 831 of Vascular Endothelial Growth Factor Receptor 1 Is a Novel Target of Methylation by SMYD3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c3e4468d29307777d30cd8ba7ee344
https://doi.org/10.1158/0008-5472.22370787.v1
https://doi.org/10.1158/0008-5472.22370787.v1
Autor:
Yoichi Furukawa, Yusuke Nakamura, Masabumi Shibuya, Takeshi Nagayasu, Kiyoshi Yamaguchi, Fabio Pittella Silva, Ryuji Hamamoto, Masaki Kunizaki
Supplementary Table 1 from The Lysine 831 of Vascular Endothelial Growth Factor Receptor 1 Is a Novel Target of Methylation by SMYD3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fb48849304dac55658f487bbba2fba
https://doi.org/10.1158/0008-5472.22370781
https://doi.org/10.1158/0008-5472.22370781
Autor:
Yoichi Furukawa, Yusuke Nakamura, Masabumi Shibuya, Takeshi Nagayasu, Kiyoshi Yamaguchi, Fabio Pittella Silva, Ryuji Hamamoto, Masaki Kunizaki
We previously identified SMYD3 as a histone methyltransferase and showed that its expression was elevated in colorectal, hepatocellular, and breast carcinomas. In the investigation of methyltransferase activity of SMYD3, we have found that vascular e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167741507c9f80cba78dd44322779fb4
https://doi.org/10.1158/0008-5472.c.6496533.v1
https://doi.org/10.1158/0008-5472.c.6496533.v1
Autor:
Yoichi Furukawa, Yusuke Nakamura, Masabumi Shibuya, Takeshi Nagayasu, Kiyoshi Yamaguchi, Fabio Pittella Silva, Ryuji Hamamoto, Masaki Kunizaki
Supplementary Figures 1-2 from The Lysine 831 of Vascular Endothelial Growth Factor Receptor 1 Is a Novel Target of Methylation by SMYD3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66e63c07865d84aff79c187c48d3f46
https://doi.org/10.1158/0008-5472.22370784
https://doi.org/10.1158/0008-5472.22370784