Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Fabio, Penna"'
Autor:
Alessio Molfino, Marc Beltrà, Maria Ida Amabile, Roberta Belli, Giovanni Birolo, Elena Belloni, Serena De Lucia, Lorena Garcia‐Castillo, Fabio Penna, Giovanni Imbimbo, Giuseppe Nigri, Barbara Pardini, Paola Costelli, Maurizio Muscaritoli
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 6, Pp 2692-2702 (2023)
Abstract Background Small non‐coding (snc)RNAs, including microRNAs and P‐element induced wimpy testis (PIWI)‐interacting‐RNAs (piRNAs), crucially regulate gene expression in both physiological and pathological conditions. In particular, some
Externí odkaz:
https://doaj.org/article/6dd9930d14424edda15aa29fd3b334a2
Autor:
Marc Beltrà, Noora Pöllänen, Claudia Fornelli, Kialiina Tonttila, Myriam Y. Hsu, Sandra Zampieri, Lucia Moletta, Samantha Corrà, Paolo E. Porporato, Riikka Kivelä, Carlo Viscomi, Marco Sandri, Juha J. Hulmi, Roberta Sartori, Eija Pirinen, Fabio Penna
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
The loss of nicotinamide adenine dinucleotide is reported to be associated with muscle mitochondrial dysfunction in murine cancer models. Here the authors show that niacin supplementation improves mitochondrial metabolism and reduces muscle wasting i
Externí odkaz:
https://doaj.org/article/ee51ca7f97a74e20ad7e2101da472762
Autor:
Fabrizio Pin, Marc Beltrà, Lorena Garcia‐Castillo, Barbara Pardini, Giovanni Birolo, Giuseppe Matullo, Fabio Penna, Denis Guttridge, Paola Costelli
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 481-494 (2022)
Abstract Background Cachexia, a syndrome frequently occurring in cancer patients, is characterized by muscle wasting, altered energy and protein metabolism and impaired myogenesis. Tumour‐derived microvesicles (TMVs) containing proteins, messenger
Externí odkaz:
https://doaj.org/article/bae6881d62c64c0fa01a8c15fe09eb44
Autor:
Marc Beltrà, Fabrizio Pin, Domiziana Costamagna, Robin Duelen, Alessandra Renzini, Riccardo Ballarò, Lorena Garcia-Castillo, Ambra Iannuzzi, Viviana Moresi, Dario Coletti, Maurilio Sampaolesi, Fabio Penna, Paola Costelli
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105480- (2022)
Summary: Skeletal muscle repair is accomplished by satellite cells (MuSCs) in cooperation with interstitial stromal cells (ISCs), but the relationship between the function of these cells and the metabolic state of myofibers remains unclear. This stud
Externí odkaz:
https://doaj.org/article/d23a3e4def1d4333a183327d1e23d406
Publikováno v:
Oncogenesis, Vol 10, Iss 1, Pp 1-13 (2021)
Abstract Cachexia is a severe complication of cancer that adversely affects the course of the disease, with currently no effective treatments. It is characterized by a progressive atrophy of skeletal muscle and adipose tissue, resulting in weight los
Externí odkaz:
https://doaj.org/article/a3367099d5984b60abb4cc747fa3d2a7
Autor:
Domiziana Costamagna, Robin Duelen, Fabio Penna, Detlef Neumann, Paola Costelli, Maurilio Sampaolesi
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 3, Pp 783-801 (2020)
Abstract Background Anorexia, body wasting, inflammation, muscle, and adipose tissue loss are hallmarks of cancer cachexia, a syndrome that affects the majority of cancer patients, impairing their ability to endure chemotherapeutic therapies and redu
Externí odkaz:
https://doaj.org/article/72d4e09cf61844cebcb3d9037f667760
Autor:
Tuuli A. Nissinen, Jaakko Hentilä, Fabio Penna, Anita Lampinen, Juulia H. Lautaoja, Vasco Fachada, Tanja Holopainen, Olli Ritvos, Riikka Kivelä, Juha J. Hulmi
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 3, Pp 514-529 (2018)
Abstract Background Cancer cachexia increases morbidity and mortality, and blocking of activin receptor ligands has improved survival in experimental cancer. However, the underlying mechanisms have not yet been fully uncovered. Methods The effects of
Externí odkaz:
https://doaj.org/article/8b4386525c204ba9bbc5c04414cf63e4
Publikováno v:
Cells, Vol 10, Iss 11, p 3150 (2021)
Cancer cachexia is a frequently neglected debilitating syndrome that, beyond representing a primary cause of death and cancer therapy failure, negatively impacts on patients’ quality of life. Given the complexity of its multisystemic pathogenesis,
Externí odkaz:
https://doaj.org/article/5cfc9d5895df420a8f92fa117f58ac2b
Autor:
Massimiliano Leigheb, Alessandro de Sire, Matteo Colangelo, Domenico Zagaria, Federico Alberto Grassi, Ottavio Rena, Patrizio Conte, Pierluigi Neri, Alessandro Carriero, Gian Mauro Sacchetti, Fabio Penna, Giuseppina Caretti, Elisabetta Ferraro
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2158 (2021)
Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarco
Externí odkaz:
https://doaj.org/article/001ae096e7824884835b0f699ea67503
Autor:
Fabio Penna, Riccardo Ballarò, Marc Beltrà, Serena De Lucia, Lorena García Castillo, Paola Costelli
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The management of cancer patients is frequently complicated by the occurrence of cachexia. This is a complex syndrome that markedly impacts on quality of life as well as on tolerance and response to anticancer treatments. Loss of body weight, wasting
Externí odkaz:
https://doaj.org/article/3e338a48c9cb4a4583edb4bf9c7bdae2