Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Fabio, Pastorino"'
Autor:
Mario Capasso, Chiara Brignole, Vito A. Lasorsa, Veronica Bensa, Sueva Cantalupo, Enrico Sebastiani, Alessandro Quattrone, Eleonora Ciampi, Marianna Avitabile, Angela R. Sementa, Katia Mazzocco, Barbara Cafferata, Gabriele Gaggero, Valerio G. Vellone, Michele Cilli, Enzo Calarco, Elena Giusto, Patrizia Perri, Sanja Aveic, Doriana Fruci, Annalisa Tondo, Roberto Luksch, Rossella Mura, Marco Rabusin, Francesco De Leonardis, Monica Cellini, Paola Coccia, Achille Iolascon, Maria V. Corrias, Massimo Conte, Alberto Garaventa, Loredana Amoroso, Mirco Ponzoni, Fabio Pastorino
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Although the overall survival of patients with NB has improved in the last years, more than 50% of high-risk patients stil
Externí odkaz:
https://doaj.org/article/dbb768f368d643d1a5a9f03a388be936
Autor:
Ezio Bonvini, Chiara Brignole, Enzo Calarco, Veronica Bensa, Elena Giusto, Patrizia Perri, Eleonora Ciampi, Maria Valeria Corrias, Simonetta Astigiano, Michele Cilli, Derik Loo, Fabio Pastorino, Mirco Ponzoni
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Introduction B7-H3 is a potential target for pediatric cancers, including neuroblastoma (NB). Vobramitamab duocarmazine (also referred to as MGC018 and herein referred to as vobra duo) is an investigational duocarmycin-based antibody-drug conjugate (
Externí odkaz:
https://doaj.org/article/c4e676297dc848ee96ef5ee33733a991
Autor:
Valeria Lucarini, Ombretta Melaiu, Silvia D’Amico, Fabio Pastorino, Patrizia Tempora, Marco Scarsella, Marco Pezzullo, Adele De Ninno, Valentina D’Oria, Michele Cilli, Laura Emionite, Paola Infante, Lucia Di Marcotullio, Maria Antonietta De Ioris, Giovanni Barillari, Rita Alaggio, Luca Businaro, Mirco Ponzoni, Franco Locatelli, Doriana Fruci
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Poor infiltration of functioning T cells renders tumors unresponsive to checkpoint-blocking immunotherapies. Here, we identified a combinatorial in situ immunomodulation strategy based on the administration of selected immunogenic
Externí odkaz:
https://doaj.org/article/7da718b9d0384f1794918c8d3fdad88d
Publikováno v:
Animal, Vol 17, Iss , Pp 100837- (2023)
The paper analyzes the impact of trade relations between the European Union (EU) and Mercosur with its member states (Argentina, and Brazil, in particular), on the adoption of legislation on animal welfare inspired by the EU model. In the first part,
Externí odkaz:
https://doaj.org/article/5a866751fa9e40079ec4775ef4634142
Autor:
Mirco Ponzoni, Tiziana Bachetti, Maria Valeria Corrias, Chiara Brignole, Fabio Pastorino, Enzo Calarco, Veronica Bensa, Elena Giusto, Isabella Ceccherini, Patrizia Perri
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-28 (2022)
Abstract Neuroblastoma (NB) is a pediatric tumor that originates from neural crest-derived cells undergoing a defective differentiation due to genomic and epigenetic impairments. Therefore, NB may arise at any final site reached by migrating neural c
Externí odkaz:
https://doaj.org/article/499ab520b9e04ba692ee13279c564d7e
Autor:
Davide Cangelosi, Chiara Brignole, Veronica Bensa, Roberto Tamma, Fabiana Malaguti, Barbara Carlini, Elena Giusto, Enzo Calarco, Patrizia Perri, Domenico Ribatti, Nuno André Fonseca, Joao Nuno Moreira, Alessandra Eva, Loredana Amoroso, Massimo Conte, Alberto Garaventa, Angela Rita Sementa, Maria Valeria Corrias, Mirco Ponzoni, Fabio Pastorino
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104300- (2022)
Summary: Background: Neuroblastoma (NB) represents the most frequent form of extra-cranial solid tumour of infants, responsible for 15% of childhood cancer deaths. Nucleolin (NCL) prognostic value in NB was investigated. Methods: NCL protein expressi
Externí odkaz:
https://doaj.org/article/7c7feb7bb2a447eba44682ff9676b2fb
Autor:
Chiara Brignole, Veronica Bensa, Nuno A. Fonseca, Genny Del Zotto, Silvia Bruno, Ana F. Cruz, Fabiana Malaguti, Barbara Carlini, Fabio Morandi, Enzo Calarco, Patrizia Perri, Vera Moura, Laura Emionite, Michele Cilli, Francesco De Leonardis, Annalisa Tondo, Loredana Amoroso, Massimo Conte, Alberto Garaventa, Angela R. Sementa, Maria V. Corrias, Mirco Ponzoni, Joao N. Moreira, Fabio Pastorino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Nucleolin (NCL) is a protein overexpressed and partially localized on the cell surface of tumor cells of adult cancers. Li
Externí odkaz:
https://doaj.org/article/74d59ac150f64c2ab3aaf5e3f878f108
Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib
Autor:
Diana Corallo, Fabio Pastorino, Marcella Pantile, Elena Mariotto, Federico Caicci, Giampietro Viola, Mirco Ponzoni, Gian Paolo Tonini, Sanja Aveic
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Despite reported advances, acquired resistance to tyrosine kinase inhibitors still represents a serious problem in successful cancer treatment. Among this class of drugs, ponatinib (PON) has been shown to have notable long-term ef
Externí odkaz:
https://doaj.org/article/3544c2c213fe41539b897649ac845d8c
Autor:
Fabio Pastorino, Mario Capasso, Chiara Brignole, Serena Giglio, Veronica Bensa, Sueva Cantalupo, Vito Alessandro Lasorsa, Annalisa Tondo, Rossella Mura, Angela Rita Sementa, Alberto Garaventa, Mirco Ponzoni, Loredana Amoroso
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11236 (2022)
Neuroblastoma (NB) is the most common extracranial solid tumor encountered in childhood. Although there has been significant improvement in the outcomes of patients with high-risk disease, the prognosis for patients with metastatic relapse or refract
Externí odkaz:
https://doaj.org/article/1195b54c0f9b40d39b51b6b67ca8cb07
Publikováno v:
Biología Acuática, Iss 35 (2020)
El trabajo se inicia con una descripción de los criterios propios del derecho, que influyeron en la lógica de sus disposiciones en relación con los bienes de la naturaleza en general y del agua en particular y que explican cómo, aún hoy, las cat
Externí odkaz:
https://doaj.org/article/be45e9c449e34613bbca0a464f9cd437