Comparative effectiveness of chest ultrasound, chest X-ray and computer-aided diagnostic (CAD) for tuberculosis diagnosis in low-resource setting: study protocol for a cross-sectional study from Ethiopia

Autor: Giacomo Guido, Worku Nigussa, Sergio Cotugno, Birhanu Kenate Sori, Flavio Antonio Bobbio, Berhanu Gulo, Luigi Pisani, Fabio Manenti, Mulugeta Miressa, Francesco Cavallin, Surra Abata, Francesco Vladimiro Segala, Abdi Reta, Ottavia Tulome, Giovanni Putoto, Roberta Iatta, Antonino Tuttolomondo, Nicola Veronese, Mario Barbagallo, Annalisa Saracino, Francesco Di Gennaro

Publikováno v: Frontiers in Public Health, Vol 12 (2024)

IntroductionEarly and accurate diagnosis of pulmonary tuberculosis (TB) is crucial for timely treatment and prevention of transmission, but diagnostic challenges persist due to complex symptoms and limitations in diagnostic tools. Chest X-ray (CXR) i

Externí odkaz: https://doaj.org/article/6c7ea1d433694ec288c5d8f2610970dc

Protocol for an evaluation of the initiation of an integrated longitudinal outpatient care model for severe chronic non-communicable diseases (PEN-Plus) at secondary care facilities (district hospitals) in 10 lower-income countries

Autor: Archana Shrestha, Biraj Man Karmacharya, Robert Kalyesubula, Isaac Ssinabulya, Zipporah Ali, Alma J Adler, Ana Olga Mocumbi, Neil Gupta, Meghnath Dhimal, Bhagawan Koirala, Gedeon Ngoga, Symaque Dusabeyezu, Gene Kwan, Gene Bukhman, Lilian Mbau, Beatriz Manuel, Giovanni Putoto, Santigie Sesay, Emily B Wroe, Yogeshwar Kalkonde, Sergio Chicumbe, Lauren Brown, Abha Shrestha, Lucia González, Matthew M Coates, Jones K Masiye, Mary Theodory Mayige, Wubaye Walelgne Dagnaw, Chiyembekezo Kachimanga, Ana Mocumbi, Ryan McBain, Apoorva Gomber, Fabio Manenti, Roma Chilengi, Yogesh Jain, Sam Patel, Gladwell Gathecha, Julie Makani, Amy McLaughlin, Celina Trujillo, Laura Drown, Reuben Mutagaywa, Todd Ruderman, Gina Ferrari, Chantelle Boudreaux, Humberto Muquingue, Mary Mayige, Jonathan Chiwanda Banda, Andrea Atzori, Neusa Bay, Wondu Bekele, Victoria M Bhambhani, Remy Bitwayiki Nkwiro, Dawson Calixte, Katia Domingues, Darius Fenelon, Innocent Kamali, Catherine Karekezi, Alexio Mangwiro, Fastone Mathew Goma, Emmanuel Mensah, Nicole Mocumbi Salipa, Alvern Mutengerere, Marta Patiño, Devashri Salvi, Fameti Taero, Emílio Tostão, Sterman Toussaint, Abhijit Gadewar, Sunil Jadhao, Chetanya Malik, Alma Adler, Victoria Bhambhani, Susan Donnellan, Kaita Domingues, Sheila Klassen, Andrew Marx, Maia Olsen, Catherine Player, Ramon Ruiz, Ada Thapa, Leslie Wentworth, Allison Westervelt, Ariana Wolgin, Emily Yale, Michael Abiyu, Lemma Ayele, Zelalem Mengistu, Temesgen Sileshi, Natnael Alemayehu, Natnael A Abebe, Nancy Larco, Gideon Ayodo, Peter Mokaya, Jones Masiye, Evelyn Chibwe, Noel Kasomekera, Nicole M Salipa, Riaze Rafik, Lucy Ramirez, Shiva Adhikary, Krishna Aryal, Phanindra Baral, Biraj Karmachaya, Abhinav Vaidhya, Ann Akiteng, Frank Mugabe, Sarah Asio Eragu, Bernard Bukar, Namasiku Siyumbwa, Wibroad Mutale, Kudakwashe Madzeke, Alaisa Mbiriri, Nyamayaro Wencelas, Porika Nyawai, Abaden Svisva, Laura Ruckstuhl

Publikováno v: BMJ Open, Vol 14, Iss 1 (2024)

Introduction The Package of Essential Noncommunicable Disease Interventions—Plus (PEN-Plus) is a strategy decentralising care for severe non-communicable diseases (NCDs) including type 1 diabetes, rheumatic heart disease and sickle cell disease, to

Externí odkaz: https://doaj.org/article/992bdf24e8ec4d74866d7214d725d384

Priority age targets for COVID-19 vaccination in Ethiopia under limited vaccine supply

Autor: Margherita Galli, Agnese Zardini, Worku Nigussa Gamshie, Stefano Santini, Ademe Tsegaye, Filippo Trentini, Valentina Marziano, Giorgio Guzzetta, Mattia Manica, Valeria d’Andrea, Giovanni Putoto, Fabio Manenti, Marco Ajelli, Piero Poletti, Stefano Merler

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract The worldwide inequitable access to vaccination claims for a re-assessment of policies that could minimize the COVID-19 burden in low-income countries. Nine months after the launch of the national vaccination program in March 2021, only 3.4%

Externí odkaz: https://doaj.org/article/0022b2561211498fb6d2c208d3b4a86f

Directed self-assembly of a xenogeneic vascularized endocrine pancreas for type 1 diabetes

Autor: Antonio Citro, Alessia Neroni, Cataldo Pignatelli, Francesco Campo, Martina Policardi, Matteo Monieri, Silvia Pellegrini, Erica Dugnani, Fabio Manenti, Maria Chiara Maffia, Libera Valla, Elisabeth Kemter, Ilaria Marzinotto, Cristina Olgasi, Alessia Cucci, Antonia Follenzi, Vito Lampasona, Eckhard Wolf, Lorenzo Piemonti

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Cell therapy for diabetes requires the combination of bioengineering and new sources of beta cells. Here, the authors report a self-assembly platform based on neonatal pig islets, human endothelial cells and native organ extracellular matrix, which i

Externí odkaz: https://doaj.org/article/2a3c8e507cd5428db6511e1934289d0e

Stool Xpert MTB/RIF as a possible diagnostic alternative to sputum in Africa: a systematic review and meta-analysis

Autor: Francesco Vladimiro Segala, Roberta Papagni, Sergio Cotugno, Elda De Vita, Maria Chiara Susini, Valeria Filippi, Ottavia Tulone, Enzo Facci, Rossana Lattanzio, Claudia Marotta, Fabio Manenti, Davide Fiore Bavaro, Giuseppina De Iaco, Giovanni Putoto, Nicola Veronese, Mario Barbagallo, Annalisa Saracino, Francesco Di Gennaro

Publikováno v: Frontiers in Public Health, Vol 11 (2023)

IntroductionWorldwide, COVID-19 pandemic lead to a large fall in the number of newly reported TB cases. In sub-Saharan Africa, microbiological diagnosis of TB is generally based on smear microscopy and Xpert MTB/RIF on sputum samples, but good qualit

Externí odkaz: https://doaj.org/article/5724c38a65b1435a86ee4dad22259c97