Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fabienne Regnier"'
Autor:
Marion V. Guerin, Fabienne Regnier, Vincent Feuillet, Lene Vimeux, Julia M. Weiss, Georges Bismuth, Gregoire Altan-Bonnet, Thomas Guilbert, Maxime Thoreau, Veronica Finisguerra, Emmanuel Donnadieu, Alain Trautmann, Nadège Bercovici
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Interferons have been shown to mediate tumour rejection. Here, in a spontaneous mouse model of breast cancer, the authors show that this is disrupted owing to high levels of TGFβ produced in the tumour.
Externí odkaz:
https://doaj.org/article/4998cfedc6d240aeaec2f8249ea1a3ed
Autor:
Maxime Thoreau, Fabienne Regnier, Alain Trautmann, Nadege Bercovici, Marion v Guerin, Lene Vimeux, Matthieu Benard, Hweixian L Penny
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Tumor relapse constitutes a major challenge for anti-tumoral treatments, including immunotherapies. Indeed, most cancer-related deaths occur during the tumor relapse phase.Methods We designed a mouse model of tumor relapse in which mice tr
Externí odkaz:
https://doaj.org/article/eb416a1a1ddb4c35877b667537985dcb
Autor:
Julia M. Weiss, Marion V. Guérin, Fabienne Regnier, Gilles Renault, Isabelle Galy-Fauroux, Lene Vimeux, Vincent Feuillet, Elisa Peranzoni, Maxime Thoreau, Alain Trautmann, Nadège Bercovici
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Regressing tumors are usually associated with a large immune infiltrate, but the molecular and cellular interactions that govern a successful anti-tumor immunity remain elusive. Here, we have triggered type I Interferon (IFN) signaling in a breast tu
Externí odkaz:
https://doaj.org/article/4ac923f415d746199290f548e5b954c5
Autor:
Shu-Fang Wang, Stéphane Fouquet, Maxime Chapon, Hélène Salmon, Fabienne Regnier, Karine Labroquère, Cécile Badoual, Diane Damotte, Pierre Validire, Eve Maubec, Nicolas B Delongchamps, Aurélie Cazes, Laure Gibault, Marylène Garcette, Marie-Caroline Dieu-Nosjean, Marc Zerbib, Marie-Françoise Avril, Armelle Prévost-Blondel, Clotilde Randriamampita, Alain Trautmann, Nadège Bercovici
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17621 (2011)
To improve cancer immunotherapy, a better understanding of the weak efficiency of tumor-infiltrating T lymphocytes (TIL) is necessary. We have analyzed the functional state of human TIL immediately after resection of three types of tumors (NSCLC, mel
Externí odkaz:
https://doaj.org/article/d2afef42ddaf41d89e21bed6e32dffde
Autor:
Fabienne Regnier, Alain Trautmann, Grégoire Altan-Bonnet, Lene Vimeux, Marion V. Guérin, Julia Miriam Weiss, Vincent Feuillet, Nadège Bercovici, Emmanuel Donnadieu
Publikováno v:
Live Talks.
Background Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce a strong production of IFNα/β and the rejection of transplanted primary tumors. However, the efficacy of such therapeutic
Autor:
Emmanuel Donnadieu, Thomas Guilbert, Vincent Feuillet, Fabienne Regnier, Maxime Thoreau, Veronica Finisguerra, Alain Trautmann, Lene Vimeux, Nadège Bercovici, Julia Miriam Weiss, Marion V. Guerin, Gilles Renault
Publikováno v:
Nature Communications
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-11998-w⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-11998-w⟩
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-11998-w⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-11998-w⟩
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Type I interferons (IFN) are being rediscovered as potent anti-tumoral agents. Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce strong production of IFNα/β and rejection of transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e17412bd5ea94db5b6ff7a7d04c5eb2
https://hal.archives-ouvertes.fr/hal-02404270
https://hal.archives-ouvertes.fr/hal-02404270
Autor:
Elisa Peranzoni, Thomas Guilbert, Vincent Feuillet, Julia Miriam Weiss, Gilles Renault, Maxime Thoreau, Nadège Bercovici, Fabienne Regnier, Marion Guerin, Alain Trautmann
Publikováno v:
Cancer Immunology Research. 5:A05-A05
Despite significant advances, cancer immunotherapies fail to systematically elicit tumor regression. It is therefore crucial to understand what conditions the efficacy of immune responses against solid tumors. In particular, while the involvement of
Publikováno v:
Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, 2006, 348 (3), pp.857-863. ⟨10.1016/j.bbrc.2006.07.092⟩
Biochemical and Biophysical Research Communications, Elsevier, 2006, 348 (3), pp.857-863. ⟨10.1016/j.bbrc.2006.07.092⟩
Biochemical and Biophysical Research Communications, 2006, 348 (3), pp.857-863. ⟨10.1016/j.bbrc.2006.07.092⟩
Biochemical and Biophysical Research Communications, Elsevier, 2006, 348 (3), pp.857-863. ⟨10.1016/j.bbrc.2006.07.092⟩
HSiah1 and 2 are members of the Ring finger-type family of ubiquitin E3-ligase proteins. They contribute to the degradation of multiple targets by interacting with both the ubiquitin conjugating enzyme E2 and the substrate to be ubiquitylated prior t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12a5c26621d7675c69c7c906a04e18e
https://sorbonne-paris-nord.hal.science/hal-02061449
https://sorbonne-paris-nord.hal.science/hal-02061449
Autor:
Morgane Simao, Fabienne Régnier, Sarah Taheraly, Achille Fraisse, Rachida Tacine, Marie Fraudeau, Adam Benabid, Vincent Feuillet, Mireille Lambert, Jérôme Delon, Clotilde Randriamampita
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
T lymphocyte migration is an essential step to mounting an efficient immune response. The rapid and random motility of these cells which favors their sentinel role is conditioned by chemokines as well as by the physical environment. Morphological cha
Externí odkaz:
https://doaj.org/article/f31aa56e6844414fbabbb87e1b0df820
Autor:
Romain Deshayes de Cambronne, Lionel Costa, Caroline Rambaud, Martine Cohen-Salmon, Abdelouhab Bouaboud, Asmaa Tazi, Anne-Cécile Boulay, Anne-Sophie Bourrel, Agnès Fouet, Amandine Picart, Cristina Candeias, Claire Poyart, Julie Guignot, Guillaume Bouvier, Isabelle Plu, Cyril Anjou, Corinne Albiges-Rizo, Eva Faurobert
Publikováno v:
The Journal of clinical investigation
The Journal of clinical investigation, 2021, 131 (5), pp.e136737. ⟨10.1172/JCI136737⟩
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2021, 131 (5), ⟨10.1172/JCI136737⟩
J Clin Invest
The Journal of clinical investigation, 2021, 131 (5), pp.e136737. ⟨10.1172/JCI136737⟩
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2021, 131 (5), ⟨10.1172/JCI136737⟩
J Clin Invest
We are grateful to Pierre-Olivier Couraud (INSERM, Paris, France) for the gift of hCMEC/D3 cells, Alain Duperray for the gift of CHO-ICAM1 cells, Yoshikazu Takada for the gift of CHO-αvβ3 cells, and Glen Ulett for the gift of the GFP plasmid. We ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9990e6b8af3856a03b1cd06d11fc1640
https://hal.archives-ouvertes.fr/hal-03408728
https://hal.archives-ouvertes.fr/hal-03408728