Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fabienne Piras"'
Autor:
Deborah Andouard, Valentin Tilloy, Elodie Ribot, Melissa Mayeras, Daniel Diaz-Gonzalez, Chahrazed El Hamel, Fabienne Piras-Douce, Nathalie Mantel, Sophie Alain
Publikováno v:
Pathogens, Vol 12, Iss 8, p 985 (2023)
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, leading to a variety of symptoms in the unborn child that range from asymptomatic to death in utero. Our objective was to better understand the mechanisms of placental i
Externí odkaz:
https://doaj.org/article/8fb319e4c9fb489b86c9cb5ab479ad80
Autor:
Ilona Baraniak, Ariane C. Gomes, Isabella Sodi, Toby Langstone, Emily Rothwell, Claire Atkinson, Sylvie Pichon, Fabienne Piras-Douce, Paul D. Griffiths, Matthew B. Reeves
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 45-54 (2019)
Background: Human cytomegalovirus (HCMV) causes a ubiquitous infection which can pose a significant threat for immunocompromised individuals, such as those undergoing solid organ transplant (SOT). Arguably, the most successful vaccine studied to date
Externí odkaz:
https://doaj.org/article/08a927984721435f8ea3079281257f12
Autor:
Marie Garinot, Fabienne Piras-Douce, Patricia Probeck, Véronique Chambon, Kucku Varghese, Yuanqing Liu, Ernesto Luna, Donald Drake, Jean Haensler
Publikováno v:
International Journal of Pharmaceutics: X, Vol 2, Iss , Pp 100054- (2020)
A structure-activity study was conducted to identify the structural characteristics underlying the adjuvant activity of straight (i.e. non-crosslinked) polyacrylate polymers (PAAs) in order to select a new PAA adjuvant candidate for future clinical d
Externí odkaz:
https://doaj.org/article/c058087f24e54b13820a3efc5985a8b8
Autor:
Fabienne Piras-Douce, Karine Broudic, Emilie Chautard, Franck Raynal, Virginie Courtois, Sylviane Gautheron, Nathalie Mantel
Publikováno v:
Vaccine. 41:1457-1470
Publikováno v:
Journal of applied toxicology : JATREFERENCES.
Herpes simplex virus type 2 (HSV-2) is the most common cause of genital disease worldwide. The development of an effective HSV-2 vaccine would significantly impact global health based on the psychological distress caused by genital herpes for some in
Autor:
Martha Erika Navarro Sanchez, Fabienne Piras-Douce, Nathalie Mantel, Manuel Vangelisti, Sylviane Gautheron, Franck Raynal, Alix Raquin, Yves Girerd-Chambaz
Publikováno v:
Vaccine
Highlights • vYF-247 was cloned from YF-VAX and adapted for growth in serum-free Vero cells. • vYF-247 selected by safety/immunogenicity/efficacy criteria in small animal models. • vYF-247 was less neurovirulent than Stamaril and YF-VAX. • vY
Publikováno v:
Toxicology and Applied Pharmacology. 460:116358
A full nonclinical safety package was performed to support the clinical use of SPA14, a novel liposome-based vaccine adjuvant containing the synthetic toll-like receptor 4 agonist E6020 and saponin QS21. E6020 and QS21 were tested negative for their
Autor:
Fabienne Piras-Douce, Emily Rothwell, Toby Langstone, Sylvie Pichon, Paul D. Griffiths, Ariane C Gomes, Ilona Baraniak, Matthew B. Reeves, Isabella Sodi, Claire Atkinson
Publikováno v:
EBioMedicine, Vol 50, Iss, Pp 45-54 (2019)
EBioMedicine
EBioMedicine
Background: Human cytomegalovirus (HCMV) causes a ubiquitous infection which can pose a significant threat for immunocompromised individuals, such as those undergoing solid organ transplant (SOT). Arguably, the most successful vaccine studied to date
Autor:
Danielle Salha, Marin Ming, Nidhi Kapoor, Kimberley Williams, Pappachan E. Kolattukudy, Beata Gajewska, Lidice Bernardo, Fabienne Piras, Leslie G. Chan, Anke Pagnon, Jin Su, Lucy Gisonni-Lex
Publikováno v:
Vaccine. 37:2960-2966
Potency assays for vaccine products are an important regulatory requirement, and are used to assess product quality and consistency prior to lot release for clinical testing. Ideally they measure an established correlate of efficacy or protection. In
Autor:
Ernesto Luna, Donald Drake, Jean Haensler, Yuanqing Liu, Kucku Varghese, Marie Garinot, Fabienne Piras-Douce, Patricia Probeck, Véronique Chambon
Publikováno v:
International Journal of Pharmaceutics: X
International Journal of Pharmaceutics: X, Vol 2, Iss, Pp 100054-(2020)
International Journal of Pharmaceutics: X, Vol 2, Iss, Pp 100054-(2020)
A structure-activity study was conducted to identify the structural characteristics underlying the adjuvant activity of straight (i.e. non-crosslinked) polyacrylate polymers (PAAs) in order to select a new PAA adjuvant candidate for future clinical d