Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fabienne Mésange"'
Autor:
Marc Poirot, Jean-Charles Faye, Mohamed Sebbar, Jean-Claude Guillemot, Francis Bayard, Pascual Ferrara, Joël Capdevielle, Fabienne Mésange
Publikováno v:
Bioconjug Chem
Bioconjug Chem, 2002, 13, pp.766-72
Bioconjug Chem, 2002, 13, pp.766-72
Our quest to identify target proteins involved in the activity of tamoxifen led to the design of photoaffinity ligand analogues of tamoxifen able to cross-link such proteins. A new tritiated photoprobe, 4-(2-morpholinoethoxy)benzophenone (MBoPE), was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4371279ce7045ed10c7d263a294f396
https://www.hal.inserm.fr/inserm-00090779
https://www.hal.inserm.fr/inserm-00090779
Autor:
Fabienne Mésange, Marc Poirot, Blandine Kedjouar, Francis Bayard, Frédéric Delarue, Jean-Charles Faye
Publikováno v:
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 1999, 57, pp.657-61
Biochemical Pharmacology, Elsevier, 1999, 57, pp.657-61
The antiestrogen binding site (AEBS) is a membranous protein complex that has been shown to be intimately linked with the antiproliferative and antiretroviral effects of certain antiestrogenic compounds such as tamoxifen (Tx). Various specific ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98625f71f05cc3fb493cacd5f1c61426
https://www.hal.inserm.fr/inserm-00090781
https://www.hal.inserm.fr/inserm-00090781
Autor:
Mohamed Sebbar, Fabienne Mésange, Marc Poirot, Jean-Charles Faye, Francis Bayard, Frédéric Delarue, Joël Capdevielle, Pascual Ferrara, Jean-Claude Guillemot, Blandine Kedjouar
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 1998, 334 ( Pt 1), pp.107-12
Biochemical Journal, Portland Press, 1998, 334 ( Pt 1), pp.107-12
A tritiated photoaffinity labelling analogue of tamoxifen, [(2-azido-4-benzyl)-phenoxy]-N-ethylmorpholine (azido-MBPE), was used to identify the anti-oestrogen-binding site (AEBS) in rat liver tissue [Poirot, Chailleux, Fargin, Bayard and Faye (1990)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd631f437ba0c6035f2dfa7881f3078
https://www.hal.inserm.fr/inserm-00090782
https://www.hal.inserm.fr/inserm-00090782
Publikováno v:
Journal of receptor research. 14(1)
We previously demonstrated that, in addition to the estrogen receptor, the Antiestrogen Binding Site (ABS) is also a potent mediator of the antitumorous activity of the clinical drug tamoxifen. Because of reported discrepancies in the binding paramet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640e89c03a3cffe040206cc75d7f3eab
https://pubmed.ncbi.nlm.nih.gov/8158580
https://pubmed.ncbi.nlm.nih.gov/8158580
Publikováno v:
Journal of receptor research. 14(1)
Our knowledge of the biological role of the antiestrogen binding site ABS in the antitumoral activity of tamoxifen, will be increased with the determination of its coding gene sequence. To this end our team has for some time attempted to purify this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aca91ef3604d1869329c35f90d488b1
https://pubmed.ncbi.nlm.nih.gov/8158581
https://pubmed.ncbi.nlm.nih.gov/8158581
Autor:
Marie-Ange Dupont, Fabienne Mésange, Nicole Gas, Catherine Zanibellato, Martine Garnier, Francis Bayard, Jean-Charles Faye
Publikováno v:
Experimental cell research. 205(1)
Benzylphenoxyethanamine derivatives are known to display antiproliferative activities on tumor cell lines consistently with their binding affinity to the microsomal antiestrogen binding site. In the present study we show that pyrrolidinobenzylphenoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e243b34267c2980348cc831b24d7e44
https://pubmed.ncbi.nlm.nih.gov/8453993
https://pubmed.ncbi.nlm.nih.gov/8453993