Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fabienne Leidel"'
Publikováno v:
Viruses, Vol 13, Iss 5, p 811 (2021)
Prion diseases like scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt–Jakob disease (CJD) in humans are fatal neurodegenerative diseases characterized by the conformational conversion of the normal, mainly α-helical
Externí odkaz:
https://doaj.org/article/7fffca17497746de968e8ebb1acea10f
Autor:
Armin Giese, Paul Tavan, Fabienne Leidel, Hans A. Kretzschmar, Markus Geissen, Martin H. Groschup, Martin Eiden, Thomas Hirschberger, Hermann M. Schätzl
Publikováno v:
Biochemical and Biophysical Research Communications. 445:23-29
Prion diseases are fatal neurodegenerative disorders, which are not curable and no effective treatment exists so far. The major neuropathological change in diseased brains is the conversion of the normal cellular form of the prion protein PrPc(C) int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9d8ed4fb44bd6f73a65f78c70bd541
https://doi.org/10.1016/j.bbrc.2014.01.122
https://doi.org/10.1016/j.bbrc.2014.01.122
Autor:
Armin Giese, Markus Geissen, Thomas Hirschberger, Martin Eiden, Hermann M. Schätzl, Paul Tavan, Fabienne Leidel, Martin H. Groschup, Hans A. Kretzschmar
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:4774-4781
Transmissible spongiform encephalopathies (TSEs) represent a group of fatal neurodegenerative disorders that can be transmitted by natural infection or inoculation. TSEs include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaa4512f0847c6122682d055675cfbe
https://doi.org/10.1128/aac.00151-11
https://doi.org/10.1128/aac.00151-11
Autor:
Wolfgang Zinth, Song Shi, Francisco J Pan-Montojo, Jens Wagner, Armin Giese, Thomas Hirschberger, Kai Bötzel, Sergey Ryazanov, Gerda Mitteregger-Kretzschmar, Henning Urlaub, Johannes Levin, Jens Pilger, Hans A. Kretzschmar, Felix Schmidt, Tobias Frank, Catharina Prix, Paul Tavan, Ulrike Teichmann, Jochen H. Weishaupt, Uwe Bertsch, Markus Geissen, Julian J. Krauth, Fabienne Leidel, Manfred Uhr, Mathias Bähr, Andreas A. Deeg, Matthias Samwer, Christian Griesinger, Markus Zweckstetter, Martin H. Groschup, Andrei Leonov, Martin Eiden
Publikováno v:
Acta Neuropathologica
Wagner, J, Ryazanov, S, Leonov, A, Levin, J, Shi, S, Schmidt, F, Prix, C, Pan-Montojo, F, Bertsch, U, Mitteregger-Kretzschmar, G, Geissen, M, Eiden, M, Leidel, F, Hirschberger, T, Deeg, A A, Krauth, J J, Zinth, W, Tavan, P, Pilger, J, Zweckstetter, M, Frank, T, Bähr, M, Weishaupt, J H, Uhr, M, Urlaub, H, Teichmann, U, Samwer, M, Bötzel, K, Groschup, M, Kretzschmar, H, Griesinger, C & Giese, A 2013, ' Anle138b : A novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease ', Acta Neuropathologica, vol. 125, no. 6, pp. 795-813 . https://doi.org/10.1007/s00401-013-1114-9
Acta neuropathologica 125(6), 795-813 (2013). doi:10.1007/s00401-013-1114-9
Acta Neuropathologica, 125(6), 795-813. Springer Verlag
Wagner, J, Ryazanov, S, Leonov, A, Levin, J, Shi, S, Schmidt, F, Prix, C, Pan-Montojo, F, Bertsch, U, Mitteregger-Kretzschmar, G, Geissen, M, Eiden, M, Leidel, F, Hirschberger, T, Deeg, A A, Krauth, J J, Zinth, W, Tavan, P, Pilger, J, Zweckstetter, M, Frank, T, Bähr, M, Weishaupt, J H, Uhr, M, Urlaub, H, Teichmann, U, Samwer, M, Bötzel, K, Groschup, M, Kretzschmar, H, Griesinger, C & Giese, A 2013, ' Anle138b : A novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease ', Acta Neuropathologica, vol. 125, no. 6, pp. 795-813 . https://doi.org/10.1007/s00401-013-1114-9
Acta neuropathologica 125(6), 795-813 (2013). doi:10.1007/s00401-013-1114-9
Acta Neuropathologica, 125(6), 795-813. Springer Verlag
In neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and prion diseases, deposits of aggregated disease-specific proteins are found. Oligomeric aggregates are presumed to be the key neurotoxic agent. Here we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a56d941b2d4372a3c8fbfc7ff0362f1
https://hdl.handle.net/11858/00-001M-0000-0018-DADA-D11858/00-001M-0000-0018-DAD8-211858/00-001M-0000-0013-B22A-911858/00-001M-0000-0013-B22D-3
https://hdl.handle.net/11858/00-001M-0000-0018-DADA-D11858/00-001M-0000-0018-DAD8-211858/00-001M-0000-0013-B22A-911858/00-001M-0000-0013-B22D-3
Publikováno v:
Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 3 (2012)
Frontiers in Psychiatry, Vol 3 (2012)
Transmissible spongiform encephalopathies (TSE) are characterized by the misfolding of the host encoded prion protein (PrP(C)) into a pathogenic isoform (PrP(Sc)) which leads to the accumulation of β-sheet-rich fibrils and subsequent loss of neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e917ef281fbce7aa9e73007a20a3eea4
Autor:
Christine Fast, Armin Giese, Hans A. Kretzschmar, Markus Geissen, Martin Eiden, Uwe Bertsch, Paul Tavan, Fabienne Leidel, Hermann M. Schätzl, Thomas Hirschberger, Martin H. Groschup
Publikováno v:
ChemMedChem. 6(10)
Transmissible spongiform encephalopathies (TSE) or prion diseases belong to a category of fatal and so far untreatable neurodegenerative conditions. All prion diseases are characterized by both degeneration in the central nervous system (CNS) in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69879d0213e32a7f017221fbf01bd9f
https://pubmed.ncbi.nlm.nih.gov/21755599
https://pubmed.ncbi.nlm.nih.gov/21755599