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Autor:
James E. Crooks, Emmanuel Scotet, Richard Breathnach, Andrew Sandstrom, Cassie Marie Peigné, Marie Claude Gesnel, Alexandra Leger, Fabienne Konczak, Marc Bonneville, Erin J. Adams
Publikováno v:
Immunity. 40(4)
SummaryIn humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections, including Mycobacterium tuberculosis, through recognition of small pyrophosphate containing organic molecules known as phosphoantigens (pAgs). Key to pAg-mediated activat