Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fabienne Hamester"'
Autor:
Joanna Kempska, Leticia Oliveira-Ferrer, Astrid Grottke, Minyue Qi, Malik Alawi, Felix Meyer, Kerstin Borgmann, Fabienne Hamester, Kathrin Eylmann, Maila Rossberg, Daniel J. Smit, Manfred Jücker, Elena Laakmann, Isabell Witzel, Barbara Schmalfeldt, Volkmar Müller, Karen Legler
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe PI3K/AKT pathway is activated in 43-70% of breast cancer (BC)-patients and promotes the metastatic potential of BC cells by increasing cell proliferation, invasion and radioresistance. Therefore, AKT1-inhibition in combination with ra
Externí odkaz:
https://doaj.org/article/7882ba2141484a4e949b72c38b608411
Autor:
Fabienne Hamester, Christine Stürken, Karen Legler, Kathrin Eylmann, Katrin Möller, Maila Roßberg, Christian Gorzelanny, Alexander T. Bauer, Sabine Windhorst, Barbara Schmalfeldt, Elena Laakmann, Volkmar Müller, Isabell Witzel, Leticia Oliveira-Ferrer
Publikováno v:
Cells, Vol 11, Iss 20, p 3275 (2022)
Breast cancer (BC) is the second-most common cause of brain metastases (BM) and BCBM patients have a reduced quality of life and a poor prognosis. Hyaluronan (HA), and in particular the hyaluronidase Hyal-1, has been already linked to the development
Externí odkaz:
https://doaj.org/article/f82c5d877d014fd1afcd83025381fe31
Autor:
Thorsten Schinke, Justine Münsterberg, Markus Glatzel, Monja Gandrass, Cecile L. Maire, Michaela Wrage, Katharina Besler, Stefan Steurer, Jakob Matschke, Jana Karbanová, Stefan Werner, Leticia Oliveira-Ferrer, Güntac Uzunoglu, Harriet Wikman, Denis Corbeil, Stefan W. Schneider, Katrin Lamszus, Jose Ramon Robador, Svenja Schneegans, Alexander Bauer, Andrea Kristina Horst, Yogesh K. Vashist, Desiree Loreth, Laura Brylka, Klaus Pantel, Fabienne Hamester
Publikováno v:
Neuro-Oncology. 22:955-966
Background Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis. The aim of our study was to investigate the role of acti
Autor:
Fabienne Hamester, Christine Stürken, Ceren Saygi, Minyue Qi, Karen Legler, Christian Gorzelanny, José R. Robador, Barbara Schmalfeldt, Elena Laakmann, Volkmar Müller, Isabell Witzel, Leticia Oliveira-Ferrer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1900
International Journal of Molecular Sciences, Vol 23, Iss 1900, p 1900 (2022)
International Journal of Molecular Sciences, Vol 23, Iss 1900, p 1900 (2022)
Brain metastases (BM) represent a growing problem for breast cancer (BC) patients. Recent studies have demonstrated a strong impact of the BC molecular subtype on the incidence of BM development. This study explores the interaction between BC cells o
Autor:
Fabienne Hamester, Karin Milde-Langosch, Barbara Schmalfeldt, Yi Ding, Kathrin Eylmann, Beatrice Wichert, Nicole Kelle, Maila Rossberg, Leticia Oliveira-Ferrer, Sascha Kürti, Karen Legler
Publikováno v:
British Journal of Cancer
BackgroundMaturation of complex N-glycans involves the action of Golgi mannosidases and plays a major role in cancer progression. We recently showed a favourable prognostic role of α-mannosidase MAN1A1 in breast cancer mainly caused by alteration of