Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Fabienne Godin"'
Autor:
Elodie Villalonga, Christine Mosrin, Thierry Normand, Caroline Girardin, Amandine Serrano, Bojan Žunar, Michel Doudeau, Fabienne Godin, Hélène Bénédetti, Béatrice Vallée
Publikováno v:
Cells, Vol 12, Iss 5, p 805 (2023)
LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) are serine/threonine and tyrosine kinases and the only two members of the LIM kinase family. They play a crucial role in the regulation of cytoskeleton dynamics by controlling actin filaments and microtub
Externí odkaz:
https://doaj.org/article/b3b06cb558dc48d3866e0df980021655
Autor:
Mohammed Bergoug, Michel Doudeau, Fabienne Godin, Christine Mosrin, Béatrice Vallée, Hélène Bénédetti
Publikováno v:
Cells, Vol 9, Iss 11, p 2365 (2020)
Neurofibromin is a large and multifunctional protein encoded by the tumor suppressor gene NF1, mutations of which cause the tumor predisposition syndrome neurofibromatosis type 1 (NF1). Over the last three decades, studies of neurofibromin structure,
Externí odkaz:
https://doaj.org/article/e87b3ee4bbdf4b3883a5c5c84fc2ec10
Autor:
Béatrice Vallée, Michel Doudeau, Fabienne Godin, Aurélie Gombault, Aurélie Tchalikian, Marie-Ludivine de Tauzia, Hélène Bénédetti
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47283 (2012)
BACKGROUND: Ras GTPases mediate numerous biological processes through their ability to cycle between an inactive GDP-bound form and an active GTP-bound form. Guanine nucleotide exchange factors (GEFs) favor the formation of the active Ras-GTP, wherea
Externí odkaz:
https://doaj.org/article/9f09953b68e94f839a86b19f8bb87796
Autor:
Mohammed Bergoug, Christine Mosrin, Fabienne Godin, Michel Doudeau, Iva Sosic, Marcin Suskiewicz, Béatrice Vallée, Hélène Bénédetti
Neurofibromin (Nf1) is a large multidomain protein encoded by the tumour-suppressor gene NF1. NF1 is mutated in a frequently occurring genetic disease, neurofibromatosis type I, and in various cancers. The best described function of Nf1 is its Ras-GT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed97e11006e0a18e17e2c012db60dba1
https://doi.org/10.1101/2021.12.09.471973
https://doi.org/10.1101/2021.12.09.471973
Autor:
Fabienne Godin, Denise Sy, Hélène Chautard, Béatrice Vallée, Françoise Vovelle, Hélène Bénédetti, Baptiste Legrand, Aurélie Gombault
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩
Journal of Molecular Biology, Elsevier, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩
Tfs1p and Ylr179cp are yeast proteins belonging to the PEBP family. Tfs1p, but not Ylr179cp, has been shown to interact with and inhibit Ira2p, a GTPase-activating protein of Ras. Tfs1p has been shown to be a specific inhibitor of the CPY protease an
Publikováno v:
Journal of Molecular Evolution. 54:227-234
We compared deleted copies of the seven mauritiana subfamilies of mariner transposable elements in species of the Drosophilidae. All elements were detected by PCR using the inverted terminal repeats of the Mos1 element of Drosophila mauritiana as pri
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩
Journal of Proteome Research, American Chemical Society, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩
International audience; The PEBP (phosphatidylethanolamine-binding protein) family is a large group of proteins whose human member, hPEBP1, has been shown to play multiple functions, influencing intracellular signaling cascades, cell cycle regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853b048d8d261434d28cba9b1a0380d6
https://hal.archives-ouvertes.fr/hal-00721771
https://hal.archives-ouvertes.fr/hal-00721771
Autor:
Michel Doudeau, Séverine Morisset-Lopez, Hélène Bénédetti, Béatrice Vallée, Sandrine Villette, Tobias Hévor, Chantal Pichon, Fabienne Godin, Maryvonne Ardourel
Publikováno v:
Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩
Biochemical and Biophysical Research Communications, Elsevier, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩
International audience; Neurofibromatosis type 1 is a common genetic disease that causes nervous system tumors, and cognitive deficits. It is due to mutations within the NF1 gene, which encodes the Nf1 protein. Nf1 has been shown to be involved in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1691c660781adba9d0858f3c2ab59f08
https://hal.archives-ouvertes.fr/hal-00721861
https://hal.archives-ouvertes.fr/hal-00721861
Publikováno v:
Heredity. 73:377-385
The distribution of the mariner transposable element among Drosophilidae species was investigated using three different techniques, i.e. squash blots, Southern blots and PCR amplification, using two sets of primers (one corresponding to the Inverted
Autor:
Robert Caesar, Fabienne Godin, Hélène Chautard, Béatrice Vallée, Michel Doudeau, Hélène Bénédetti, Jonas Warringer, Anders Blomberg, Aurélie Gombault
Publikováno v:
FEMS Yeast Research
FEMS Yeast Research, Oxford University Press (OUP), 2009, 9 (6), pp.867-874. ⟨10.1111/j.1567-1364.2009.00535.x⟩
FEMS Yeast Research, Oxford University Press (OUP), 2009, 9 (6), pp.867-874. ⟨10.1111/j.1567-1364.2009.00535.x⟩
International audience; The Saccharomyces cerevisiae protein Tfs1p is known as a dual protein. On the one hand, it inhibits the carboxypeptidase Y protease, and on the other, it inhibits Ira2p, a GTPase-activating protein of Ras. We managed to dissec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c0d31841d6b580a67028ca7fb139a9
https://hal.archives-ouvertes.fr/hal-00522432
https://hal.archives-ouvertes.fr/hal-00522432