Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Fabienne Glacial"'
Autor:
Huilong Luo, Bruno Saubamea, Stéphanie Chasseigneaux, Véronique Cochois, Maria Smirnova, Fabienne Glacial, Nicolas Perrière, Catarina Chaves, Salvatore Cisternino, Xavier Declèves
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Transient receptor potential vanilloid 1-4 (TRPV1-4) expression and functionality were investigated in brain microvessel endothelial cells (BMEC) forming the blood–brain barrier (BBB) from rat and human origins. In rat, Trpv1-4 were detected by qRT
Externí odkaz:
https://doaj.org/article/f367cf1943ff4c6e91196b4b2b382f4f
Autor:
Catarina Chaves, Federica Campanelli, Hélène Chapy, David Gomez-Zepeda, Fabienne Glacial, Maria Smirnova, Meryam Taghi, Johan Pallud, Nicolas Perrière, Xavier Declèves, Marie-Claude Menet, Salvatore Cisternino
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 308 (2020)
Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear. The presence of OCT1,2,3 (SLC22A1-3) in mouse, rat
Externí odkaz:
https://doaj.org/article/c2afaafc389e4db8b9cc11af61128488
Autor:
David Gomez-Zepeda, Nicolas Perrière, Fabienne Glacial, Meryam Taghi, Cérina Chhuon, Jean-Michel Scherrmann, Philippe Sergent, Amélie Moreau, Claire Denizot, Yannick Parmentier, Salvatore Cisternino, Xavier Decleves, Marie-Claude Menet
Publikováno v:
Toxicology and Applied Pharmacology. 465:116456
Autor:
Nicolas Perrière, Bruno Saubaméa, Sandrine Bourdoulous, David M. Smadja, Stéphanie Chasseigneaux, Huilong Luo, Véronique Cochois, Nina Choublier, Elisa Rossi, Pierre-Olivier Couraud, Maria Smirnova, Xavier Declèves, Salvatore Cisternino, Fabienne Glacial, Marie-Claude Menet
Publikováno v:
Molecular Pharmaceutics
Molecular Pharmaceutics, American Chemical Society, 2019, ⟨10.1021/acs.molpharmaceut.8b01252⟩
Molecular Pharmaceutics, American Chemical Society, 2019, ⟨10.1021/acs.molpharmaceut.8b01252⟩
International audience; The effect of cannabidiol (CBD), a high-affinity agonist of the transient receptor potential vanilloid-2 (TRPV2) channel, has been poorly investigated in human brain microvessel endothelial cells (BMEC) forming the blood−bra
Autor:
Jean-François Ghersi-Egea, Mathieu Santin, Christiane Charriaut-Marlangue, Mickael Tanter, Fabienne Glacial, Luigi Titomanlio, Stéphane Lehéricy, Zsolt Csaba, Charlie Demene, Pierre-Louis Leger, Pascal Dournaud, Bérard Coqueran, Stéphane Auvin, Iolanda Parente, Alice Jacquens, Isabelle Margaill, Homa Adle-Biassette, Jean-François Aubry, Pierre Gressens, Charlotte Constans, Nicolas Perrière, Tania Vitalis
Publikováno v:
Neuropathology and Applied Neurobiology
Neuropathology and Applied Neurobiology, 2021, 47 (2), pp.297-315. ⟨10.1111/nan.12665⟩
Neuropathology and Applied Neurobiology, 2021, 47 (2), pp.297-315. ⟨10.1111/nan.12665⟩
We introduce a novel approach based on agonist‐induced internalization of a neuronal G protein‐coupled receptor widely distributed in the mammalian brain, the somatostatin receptor type 2 (SST2).This approach provides an alternative and simple ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cf08e65f5f6f615d024a87931ccdae
https://hal.science/hal-03818501
https://hal.science/hal-03818501
Autor:
Dominique Crété, Hélène Chapy, Sophie Potin, Fabienne Glacial, Kayathiri Ganeshamoorthy, Pierre-Olivier Couraud, Aude Jacob, Jean-Michel Scherrmann, Xavier Declèves
Publikováno v:
Brain Research. 1613:27-36
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor activated by a variety of widespread persistent environmental pollutants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). It can transactivate the expression of several
Autor:
Fabienne Glacial, Christian Federici, Fabrice Chrétien, François Guillonneau, Luc Camoin, Kayathiri Ganeshamoorthy, Pierre-Olivier Couraud, Anny-Claude Luissint
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism; Vol 32
Journal of Cerebral Blood Flow & Metabolism
Journal of Cerebral Blood Flow & Metabolism
The blood—brain barrier (BBB) selectively controls the exchanges between the blood and the brain: it is formed by tight junctions (TJs) between adjacent microvascular endothelial cells. The transmembrane protein claudin-5 is known as a key TJ prote
Autor:
Laura Lagartera, Harry P. de Koning, Anthonius A. Eze, Kayathiri Ganeshamoorthy, Florence Miller, Carlos H. Ríos Martínez, Christophe Dardonville, Marcel Kaiser, Fabienne Glacial, Tomás Herraiz
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2015, 59 (2), pp.890-904. ⟨10.1128/AAC.03958-14⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Antimicrobial Agents and Chemotherapy, 2015, 59 (2), pp.890-904. ⟨10.1128/AAC.03958-14⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Copyright © 2015 American Society for Microbiology. All Rights Reserved. Treatment of late-stage sleeping sickness requires drugs that can cross the blood-brain barrier (BBB) to reach the parasites located in the brain. We report here the synthesis
Autor:
Fabienne Glacial, Nicolas Perrière, Catherine Driancourt, Oriane Guillevic, Julie Boyer-Di Ponio, Fida El-Ayoubi, Maeva Godet, Pierre Olivier Couraud, Kayathiri Ganeshamoorthy, Georges Uzan
Publikováno v:
PLoS ONE
PLoS ONE, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
PLoS ONE, Vol 9, Iss 1, p e84179 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. 〈10.1371/journal.pone.0084179〉
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
PLoS ONE, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
PLoS ONE, Vol 9, Iss 1, p e84179 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. 〈10.1371/journal.pone.0084179〉
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
International audience; OBJECTIVE: The vascular system is adapted to specific functions in different tissues and organs. Vascular endothelial cells are important elements of this adaptation, leading to the concept of 'specialized endothelial cells'.
Autor:
Cédric Artus, Kayathiri Ganeshamoorthy, Nicole Ziegler, Fabienne Glacial, Stefan Liebner, Pierre-Olivier Couraud, Thomas Guilbert, Maeva Godet
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Wnt morphogens released by neural precursor cells were recently reported to control blood–brain barrier (BBB) formation during development. Indeed, in mouse brain endothelial cells, activation of the Wnt/ β-catenin signaling pathway, also known as