Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Fabienne Denhez"'
Autor:
Paul F. Goetinck, Becki French, Stefania Saoncella, So-Hyung Lee, Wendy Neveu, Fabienne Denhez, Peter C. Baciu, Sarah A. Wilcox-Adelman
Publikováno v:
Journal of Biological Chemistry. 277:12270-12274
Syndecan-4 and integrins are the primary transmembrane receptors of focal adhesions in cells adherent to extracellular matrix molecules. Syndesmos is a cytoplasmic protein that interacts specifically with the cytoplasmic domain of syndecan-4, and it
Autor:
Danny L. Brower, James A. Lorenzen, Scott E. Baker, Fabienne Denhez, Lizabeth A. Perkins, Michael B. Melnick
Publikováno v:
Development. 128:1403-1414
The initiation of gene expression in response to Drosophila receptor tyrosine kinase signaling requires the nuclear import of the MAP kinase, D-ERK. However, the molecular details of D-ERK translocation are largely unknown. In this regard, we have id
Autor:
Michael Detmar, Paul F. Goetinck, Sarah A. Wilcox-Adelman, Stefania Saoncella, Fabienne Denhez, Frank Echtermeyer, Michael Streit
Publikováno v:
Journal of Clinical Investigation. 107:R9-R14
The syndecans make up a family of transmembrane heparan sulfate proteoglycans that act as coreceptors with integrins and growth factor tyrosine kinase receptors. Syndecan-4 is upregulated in skin dermis after wounding, and, in cultured fibroblasts ad
Autor:
Stefania Saoncella, So-Hyung Lee, Paul F. Goetinck, Peter C. Baciu, Fabienne Denhez, D. Leuthardt
Publikováno v:
Journal of Cell Science. 113:315-324
Syndecan-4 is a cell surface heparan sulfate proteoglycan which, in cooperation with integrins, transduces signals for the assembly of focal adhesions and actin stress fibers in cells plated on fibronectin. The regulation of these cellular events is
Autor:
Stephen D. Robinson, Richard O. Hynes, Stefania Saoncella, Fabienne Denhez, Frank Echtermeyer, Julie Nowlen, Deane F. Mosher, Paul F. Goetinck
Publikováno v:
Proceedings of the National Academy of Sciences. 96:2805-2810
The assembly of focal adhesions and actin stress fibers by cells plated on fibronectin depends on adhesion-mediated signals involving both integrins and cell-surface heparan sulfate proteoglycans. These two cell-surface receptors interact with differ
Autor:
John P. O'Bryan, David A. Chesnutt, Fabienne Denhez, James J. Fiordalisi, Channing J. Der, Steven C. Baragona, Patricia F. Maness, Jacqueline S. Biscardi, Georg F. Buehler, Daniel W. Fults
Publikováno v:
Journal of Biological Chemistry. 271:29049-29059
Rek (retina-expressed kinase) has been identified as a putative novel receptor-type tyrosine kinase of the Axl/Tyro3 family with a potential role in neural cell development. rek clones were isolated from a chick embryonic brain cDNA library with a DN
Publikováno v:
Nucleic Acids Research. 19:6419-6425
We have previously characterized the TGF-beta 3 promoter and shown that the activity of this promoter is highly variable in different cell types. Although the promoter contains a proximal cAMP responsive element, which is critical to basal and forsko
Autor:
Seong-Jin Kim, Fabienne Denhez, Anita B. Roberts, Paturu Kondaiah, Sonia B. Jakowlew, Robert J. Lechleider, Andrew G. Geiser, Michael B. Sporn, Shinichi Watanabe, Adam B. Glick, Takafumi Noma
Publikováno v:
Annals of the New York Academy of Sciences. 593:43-50
Publikováno v:
Growth Factors. 3:139-146
Two TGF-beta s, TGF-beta 1 and 2, have previously been isolated from the mouse. Here we report the isolation of a murine TGF-beta 3 cDNA. RNAs extracted from 15-day-old mouse embryos and several mouse cell lines were reverse-transcribed. These cDNA m
Autor:
Tokuro Iwabuchi, Sarah A. Wilcox-Adelman, Paul F. Goetinck, Stefania Saoncella, Fabienne Denhez, Enzo Calautti
Publikováno v:
Glycoconjugate journal. 19(4-5)
Studies examining the role of the cell-surface heparan sulfate proteoglycan syndecan-4 have yielded a plethora of information regarding its role in both cell-matrix and growth-factor mediated signaling events. Many of the initial conclusions drawn fr