Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Fabienne Condevaux"'
Publikováno v:
Journal of Immunotoxicology, Vol 19, Iss 1, Pp 41-52 (2022)
Although an extrapolation from the clinical experience in adults can often be considered to support the pediatric use for most pharmaceutical compounds, differences in safety profiles between adult and pediatric patients can be observed. The developi
Externí odkaz:
https://doaj.org/article/791ac427c2544ba5a394ee9ffe37d225
Publikováno v:
Reproductive Toxicology. 28:230-238
The pups from 32 litters of SD rats were given 0, 1, 3 or 10 mg/kg-d of cyclosporin by oral gavage from 4 to 28 days of age. 10 mg/kg-d resulted in a persistent impairment of the primary antibody response at 10 weeks of age. Indications of systemic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d99da7f26ab219a7beba1b0943d4b07
https://doi.org/10.1016/j.reprotox.2009.04.012
https://doi.org/10.1016/j.reprotox.2009.04.012
Autor:
Guillaume Ravel, Fabienne Condevaux, Jacques Descotes, Marie-France Perron-Lepage, Marielle Christ
Publikováno v:
Journal of Immunotoxicology. 1:141-148
Pre-existing or contributing risk factors, including genetic predisposition and environmental influences, are largely thought to play a crucial (though ill-elucidated) role in the development of autoimmunity. Trichloroethylene (TCE) is a widely used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a2d55d27bf628f1e207fbc887a2557
https://doi.org/10.1080/15476910490916044
https://doi.org/10.1080/15476910490916044
Publikováno v:
Toxicology. 185:241-250
NK-cell activity as a tool for detection of immunotoxic effects of new human drugs has gained further attention when the recent European note for guidance CPMP/SWP/1042/99 was adopted. The inclusion of NK-cell activity plus distribution of lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f114b8f60d809ede37d57b1f10f2a21
https://doi.org/10.1016/s0300-483x(02)00613-3
https://doi.org/10.1016/s0300-483x(02)00613-3
Publikováno v:
Journal of Applied Toxicology. 21:431-434
The measurement of natural killer (NK) cell activity often is recommended as an endpoint for inclusion in the non-clinical immunotoxicity evaluation of environmental chemicals and pharmaceuticals. To date, most data on the impact of immunotoxicants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00569b95bac6bc9caf3cf2902d90752
https://doi.org/10.1002/jat.776
https://doi.org/10.1002/jat.776
Publikováno v:
Toxicology. 105:81-90
Lymphocyte subset counts and cytokine assays are useful to investigate the interactions of pharmaceuticals, particularly new biotechnology products, with the immune system. As no specific reagents are available to label monkey lymphocytes or to assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd84e6948b9577dcbe2e2503bff56d5
https://doi.org/10.1016/0300-483x(95)03127-2
https://doi.org/10.1016/0300-483x(95)03127-2
Publikováno v:
Toxicology Methods. 1:263-272
The use of a nonrodent species is helpful to confirm results obtained in preclinical immunotoxicity assessment in rodents. As no specific reagents are available to study lymphocyte subsets in monkeys, the cross-staining properties of a panel of comme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e97edf9da8bf2fe8f8ff89508a67783
https://doi.org/10.3109/15376519109050857
https://doi.org/10.3109/15376519109050857
Publikováno v:
Reproductive Toxicology. 26:56-57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e3949c976986fc3c2bb3f4699b12989
https://doi.org/10.1016/j.reprotox.2008.05.003
https://doi.org/10.1016/j.reprotox.2008.05.003
Publikováno v:
Toxicology Letters. 144:s34-s35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0853f58c1a93815ddea192d3ee7971f0
https://doi.org/10.1016/s0378-4274(03)90117-2
https://doi.org/10.1016/s0378-4274(03)90117-2
Autor:
Phoukham Phothirath, Fabienne Condevaux, Françoise Horand, Nadine Eltchinger, Hugues Contamin
Publikováno v:
Toxicology Letters. 180:S152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da40a8a6a13863dad321cc330b420978
https://doi.org/10.1016/j.toxlet.2008.06.334
https://doi.org/10.1016/j.toxlet.2008.06.334