Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fabienne Charles de la Brousse"'
Autor:
Michael J. Grusby, Fabienne Charles de la Brousse, Ann M. Ranger, Tim Hoey, Martin R. Hodge, H. Scott Baldwin, Laurie H. Glimcher, Ellen M. Gravallese, Craig S. Mickanin
Publikováno v:
Nature. 392:186-190
Nuclear factor of activated T cells (NF-AT) is the name of a family of four related transcription factors that may be needed for cytokine gene expression in activated lymphocytes1,2,3,4. Here we report that mice with a targeted disruption of the NF-A
Autor:
Kimiaki Maruyama, Deborah F. Pinney, Fabienne Charles de la Brousse, Alexander Faerman, Charles P. Emerson, Moshe Shani
Publikováno v:
Developmental Biology. 170(1):21-38
Quail myoD (QmyoD) is the earliest myoD family member expressed in quail somites and its transcription is initiated in response to early developmental signals. We have investigated the transcriptional regulation of QmyoD to define the cis -acting seq
Publikováno v:
Trends in Genetics. 9:151-154
Thirty years ago, Jacob and Monod described how genes are selectively switched on and off in bacterial cells 1. According to their paradigm for gene regulation, specialized DNA sequences, later termed c/s-regulatory sequences, are interpreted and mob
Autor:
Steven L. McKnight, Derek E. Piper, Adrian H. Batchelor, Fabienne Charles de la Brousse, Cynthia Wolberger
Publikováno v:
Science (New York, N.Y.). 279(5353)
GA-binding protein (GABP) is a transcriptional regulator composed of two structurally dissimilar subunits. The alpha subunit contains a DNA-binding domain that is a member of the ETS family, whereas the beta subunit contains a series of ankyrin repea
Autor:
Martin R. Hodge, Timothy Hoey, Laurie H. Glimcher, Michael J. Grusby, Ann M. Ranger, Fabienne Charles de la Brousse
Publikováno v:
Immunity. 4(4)
NF-ATp is a member of a family of genes that encodes the cytoplasmic component of the nuclear factor of activated T cells (NF-AT). In this study, we show that mice with a null mutation in the NF-ATp gene have splenomegaly with hyperproliferation of b
Autor:
Timothy Hoey, Fabienne Charles de la Brousse, Mohammed Oukka, Frederick W. Alt, Martin R. Hodge, Michael J. Grusby, Laurie H. Glimcher, Ann M. Ranger, Laurie Davidson, Ellen M. Gravallese
Publikováno v:
Immunity. (1):125-134
The NF-AT family of transcription factors activates early immune response genes such as cytokines. In the adult, NF-ATc is expressed exclusively in the lymphoid system and is induced upon lymphocyte activation. NF-ATc null mutant mice die in utero of