Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fabienne Breillout"'
Autor:
Filip Lardon, Bea Pauwels, Cindy Simoens, Fabienne Breillout, Greet G. O. Pattyn, Jan B. Vermorken, Hilde A. J. Lambrechts
Publikováno v:
Cancer chemotherapy and pharmacology
Vinflunine is an innovative microtubule inhibitor belonging to the vinca alkaloid class that possesses radiosensitising properties, which could lead to promising activity in chemoradiation studies in the clinic. In the current study, different incuba
Autor:
Gianfranco Bazzoni, Luca Paris, Elena Bononi, Fabienne Breillout, Nathalie Corvaia, Christian Bailly, Laura Tonutti
Publikováno v:
Anti-cancer drugs. 22(3)
In this study, we investigated the effects of microtubuletargeting drugs, which either destabilize (the Vinca alkaloid vincristine) or stabilize (the taxane derivative docetaxel) microtubules, on the cell–cell and cell–matrix adhesive junctions o
Publikováno v:
Anti-Cancer Drugs. 4:511-516
Navelbine (NVB) pharmacokinetics has been investigated in the dog after p.o. administration of increasing doses (0.5-8 mg/kg) and in the monkey after a single dose of 40 mg/ml. In the dog, NVB pharmacokinetic parameters, Cmax, tmax, AUC, t1/2 and Cl,
Publikováno v:
Seminars in oncology. 35(3 Suppl 3)
Autor:
Greet G. O. Pattyn, Filip Lardon, Cindy Simoens, Hilde A. J. Lambrechts, Fabienne Breillout, Bea Pauwels, Christel De Pooter, Jan B. Vermorken
Publikováno v:
BMC cancer
BMC Cancer, Vol 8, Iss 1, p 65 (2008)
BMC Cancer
BMC Cancer, Vol 8, Iss 1, p 65 (2008)
BMC Cancer
Background Vinca alkaloids are an important class of anticancer agents and semisynthetic vinca alkaloids are developed to improve the therapeutic index of this class of drugs. In the present study, a direct comparison was made between vinflunine and
Autor:
Fabienne Breillout, Annelies E. C. Korst, Bea Pauwels, Jan B. Vermorken, Filip Lardon, Christel De Pooter, Hilde A. J. Lambrechts, Greet G. O. Pattyn, Cindy Simoens
Publikováno v:
Cancer chemotherapy and pharmacology
Purpose: Vinflunine (VFL) is a novel third generation Vinca alkaloid with superior antitumour activity in preclinical models and an anticipated more favourable toxicity profile compared to the other Vinca alkaloids. Method: We investigate the radiose