Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Fabien Lamoureux"'
Autor:
Thomas Duflot, Tony Pereira, Marie‐Pierre Tavolacci, Robinson Joannidès, Frédéric Aubrun, Fabien Lamoureux, Virginie Eve Lvovschi
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 82-93 (2022)
Abstract Intravenous (i.v.) morphine is a safe, robust, and recommended treatment for severe pain using the titration principle. Despite its high efficacy, it is impacted by organizational constraints related to venous access. Nebulized (NEB) morphin
Externí odkaz:
https://doaj.org/article/06a6ff83bf344bd2b1034a191f3ccd30
Autor:
Thomas Duflot, Charlotte Laurent, Anne Soudey, Xavier Fonrose, Mouad Hamzaoui, Michèle Iacob, Dominique Bertrand, Julie Favre, Isabelle Etienne, Clothilde Roche, David Coquerel, Maëlle Le Besnerais, Safa Louhichi, Tracy Tarlet, Dongyang Li, Valéry Brunel, Christophe Morisseau, Vincent Richard, Robinson Joannidès, Françoise Stanke-Labesque, Fabien Lamoureux, Dominique Guerrot, Jérémy Bellien
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract This study addressed the hypothesis that epoxyeicosatrienoic acids (EETs) synthesized by CYP450 and catabolized by soluble epoxide hydrolase (sEH) are involved in the maintenance of renal allograft function, either directly or through modula
Externí odkaz:
https://doaj.org/article/bdccddf5b20441ff9d36a503e8db992b
Autor:
Marine Cavelier, Henri Gondé, Damien Costa, Fabien Lamoureux, Tony Pereira, Nimrod Buchbinder, Rémi Varin, Charles Hervouët
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 446 (2023)
Nicardipine hydrochloride is an anti-hypertensive drug that is used off-label to treat hypertension in children. A previous oral formulation of nicardipine hydrochloride was developed using a commercial vehicle as an excipient. However, ready-to-use
Externí odkaz:
https://doaj.org/article/f5277e31fd434afc889ac1e6205341ec
Autor:
Camille Berel, Ulysse Mossé, Julien Wils, Lauriane Cousin, Laurent Imbert, Priscille Gerardin, Boris Chaumette, Fabien Lamoureux, Vladimir Ferrafiat
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Despite its drastic efficacy in resistant psychiatric disorders, clozapine remains rarely used in youth due to its side effects. Clozapine plasma level is determined through its metabolism involving several isoforms of cytochromes 450 (CYP450) family
Externí odkaz:
https://doaj.org/article/3ef8c8046a9c4b18a7f9e924fe927b97
Autor:
Thomas Duflot, Lucile Moreau-Grangé, Clothilde Roche, Michèle Iacob, Julien Wils, Isabelle Rémy-Jouet, Anne-Françoise Cailleux, Matthieu Leuillier, Sylvanie Renet, Dongyang Li, Christophe Morisseau, Fabien Lamoureux, Vincent Richard, Gaëtan Prévost, Robinson Joannidès, Jérémy Bellien
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background This pathophysiological study addressed the hypothesis that soluble epoxide hydrolase (sEH), which metabolizes the vasodilator and anti-inflammatory epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic acids (DHETs), contri
Externí odkaz:
https://doaj.org/article/ddcb0ad6d4434a15bb7558eeef506fbb
Autor:
Sacha Sarfati, Julien Wils, Timothée Lambert, Céline Mory, Laurent Imbert, Gilles Gargala, Hélène Morisse-Pradier, Fabien Lamoureux
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1598 (2022)
Voriconazole is one of the most used antifungal azoles against pulmonary aspergillosis. Therapeutic drug monitoring (TDM) of the voriconazole concentration in plasma is recommended in clinical practice guidelines to prevent treatment failure and toxi
Externí odkaz:
https://doaj.org/article/90fdaaa81ade4f5a8dc30e7cce3c7068
Autor:
Camille Tron, Régis Bouvet, Marie-Clémence Verdier, Fabien Lamoureux, Benjamin Hennart, Christèle Dubourg, Eric Bellissant, Marie-Dominique Galibert
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 637 (2022)
In the field of pharmacogenetics, the trend is to analyze a panel of several actionable genetic polymorphisms. It may require the use of high-throughput sequencing which demands expensive reagents/instruments and specific skills to interpret results.
Externí odkaz:
https://doaj.org/article/168123fc831e4f958b1c71211710a678
Autor:
Pierre Bourgoin, Jules Lecomte, Mehdi Oualha, Lionel Berthomieu, Tony Pereira, Emeline Davril, Fabien Lamoureux, Nicolas Joram, Alexis Chenouard, Thomas Duflot
Publikováno v:
Clinical Pharmacokinetics. 62:335-348
Autor:
Léa Darnaud, Fabien Lamoureux, Cendrine Godet, Sandrine Pontier, Alexia Debard, Nicolas Venisse, Pauline Martins, Didier Concordet, Peggy Gandia
Publikováno v:
Drugs in R&D, Vol 18, Iss 4, Pp 317-321 (2018)
Abstract Background Isavuconazole is a new antifungal prodrug for the treatment of invasive aspergillosis and mucormycosis. As no clear pharmacokinetic-pharmacodynamic relationship has been established for patients, therapeutic drug monitoring is not
Externí odkaz:
https://doaj.org/article/e8262af5e4e142659e33e7d2a864af00
Autor:
Vincent Scherrer, Fabien Lamoureux, Céline Chaventre, Caroline Thill, Zoe Demailly, Jean Selim, Fabrice Bauer, Laurent Imbert, Véronique Wurtz, Vincent Compère, Thomas Clavier, Emmanuel Besnier
Publikováno v:
British Journal of Anaesthesia. 129:163-171
The Minto pharmacokinetic model is used for target-controlled infusion of remifentanil. The reliability of this model has never been evaluated during normothermic cardiac surgery with cardiopulmonary bypass (CPB). The aim of this study was to assess