Efficient Enzymatic Hydrolysis of Biomass Hemicellulose in the Absence of Bulk Water

Autor: Shaghayegh Ostadjoo, Fabien Hammerer, Karolin Dietrich, Marie-Josée Dumont, Tomislav Friščić, Karine Auclair

Publikováno v: Molecules, Vol 24, Iss 23, p 4206 (2019)

Current enzymatic methods for hemicellulosic biomass depolymerization are solution-based, typically require a harsh chemical pre-treatment of the material and large volumes of water, yet lack in efficiency. In our study, xylanase (E.C. 3.2.1.8) from

Externí odkaz: https://doaj.org/article/2389592af5624bd3a12f669dca7eec04

An Artificial Hemoprotein with Inducible Peroxidase‐ and Monooxygenase‐Like Activities

Autor: Philippe Minard, Agathe Urvoas, Thibault Di Meo, Jean-Didier Maréchal, Kalani Kariyawasam, Marie Valerio-Lepiniec, Rémy Ricoux, Fabien Hammerer, Jean-Pierre Mahy, Giuseppe Sciortino

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, 2020, ⟨10.1002/chem.202002434⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2020, ⟨10.1002/chem.202002434⟩

A new inducible artificial metalloenzyme was obtained by covalent attachment of a Mn(III)-tetraphenylporphyrin to the artificial bidomain repeat protein (A3A3')Y26C. The biohybrid was characterized by MALDI-ToF MS, circular dichroism and UV-Vis spect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00575d3fe1d5ba0ea97f698450dd938f
https://doi.org/10.1002/chem.202002434

Mechanoenzymatic Breakdown of Chitinous Material to N ‐Acetylglucosamine: The Benefits of a Solventless Environment

Autor: Tomislav Friščić, Fabien Hammerer, J. P. Daniel Therien, Karine Auclair

Publikováno v: ChemSusChem. 12:3481-3490

Chitin is not only the most abundant nitrogen-containing biopolymer on the planet, but also a renewable feedstock that is often treated as a waste. Current chemical methods to break down chitin typically employ harsh conditions, large volumes of solv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ca1c391f8576f18edf955cad44e0c1
https://doi.org/10.1002/cssc.201901310

Solvent-Free Enzyme Activity: Quick, High-Yielding Mechanoenzymatic Hydrolysis of Cellulose into Glucose

Autor: Karine Auclair, Tomislav Friščić, Jean-Louis Do, J. P. Daniel Therien, Fabien Hammerer, Leigh Loots, Christopher W. Nickels

Publikováno v: Angewandte Chemie. 130:2651-2654

Mechanochemistry enables enzymatic cleavage of cellulose into glucose without bulk solvents, acids, other aggressive reagents, or substrate pre-treatment. This clean mechanoenzymatic process (coined RAging) is also directly applicable to biomass, avo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a257e4e23644487bfb4c34926db43c1
https://doi.org/10.1002/ange.201711643

Regioselective Epoxidations by Cytochrome P450 3A4 Using a Theobromine Chemical Auxiliary to Predictably Produce N-Protected β- or γ-Amino Epoxides

Autor: Vanja Polic, Karine Auclair, Fabien Hammerer, Kin Jack Cheong

Publikováno v: Advanced Synthesis & Catalysis. 359:3983-3989

N-Protected β- and γ-amino epoxides are useful chiral synthons. We report here that the enzyme cytochrome P450 3A4 can catalyze the formation of such compounds in a regio- and stereo-selective manner, even in the presence of multiple double bonds o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::947793429fdc88ff51b94d59268c978a
https://doi.org/10.1002/adsc.201700637