Výsledky vyhledávání - "Fabien Durbesson"

Akademický článek

Quantitative fragmentomics allow affinity mapping of interactomes

Autor: Gergo Gogl, Boglarka Zambo, Camille Kostmann, Alexandra Cousido-Siah, Bastien Morlet, Fabien Durbesson, Luc Negroni, Pascal Eberling, Pau Jané, Yves Nominé, Andras Zeke, Søren Østergaard, Élodie Monsellier, Renaud Vincentelli, Gilles Travé

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Protein networks have been widely explored but most binding affinities remain unknown, limiting the quantitative interpretation of interactomes. Here the authors measure affinities of 65,000 interactions involving human PDZ domains and target sequenc

Externí odkaz: https://doaj.org/article/2abf01b5330741a686c599e55cea0dee

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Akademický článek

ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming

Publikováno v: Toxins, Vol 15, Iss 12, p 673 (2023)

Snakebite envenoming can be a life-threatening medical emergency that requires prompt medical intervention to neutralise the effects of venom toxins. Each year up to 138,000 people die from snakebites and threefold more victims suffer life-altering d

Externí odkaz: https://doaj.org/article/ec9c5b6609d8440596a5de2726789690

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Akademický článek

Display of the human mucinome with defined O-glycans by gene engineered cells

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Mucins play critical roles in maintaining the human microbiome, with their O-glycosylated tandem repeats (TRs) providing important cues for microbiota. Here, the authors develop a cellular platform for producing TRs with defined O-glycan structures t

Externí odkaz: https://doaj.org/article/052ba3410c8a4710a0be9d4b267f2de3

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Akademický článek

Endonuclease-based genotyping of the RBM as a method to track the emergence or evolution of SARS-CoV-2 variants

Autor: Eva Lopez, Margot Barthélémy, Cécile Baronti, Shirley Masse, Alessandra Falchi, Fabien Durbesson, Renaud Vincentelli, Xavier de Lamballerie, Rémi Charrel, Bruno Coutard

Publikováno v: iScience, Vol 24, Iss 11, Pp 103329- (2021)

Summary: Since the beginning of the COVID-19 pandemics, variants have emerged. Some of them display increased transmissibility and/or resistance to immune response. Most of the mutations involved in the functional adaptation are found in the receptor

Externí odkaz: https://doaj.org/article/40e3d47cc36e438991142d8e8cfecf7a

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An HMM approach expands the landscape of sesquiterpene cyclases across the kingdom Fungi

Autor: Hayat Hage, Julie Couillaud, Asaf Salamov, Margot Loussouarn-Yvon, Fabien Durbesson, Elena Ormeño, Sacha Grisel, Katia Duquesne, Renaud Vincentelli, Igor Grigoriev, Gilles Iacazio, Marie-Noëlle Rosso

Publikováno v: Microbial Genomics
Microbial Genomics, 2023, 9 (4), pp.000990. ⟨10.1099/mgen.0.000990⟩

Sesquiterpene cyclases (STC) catalyse the cyclization of the C15 molecule farnesyl diphosphate into a vast variety of mono- or polycyclic hydrocarbons and, for a few enzymes, oxygenated structures, with diverse stereogenic centres. The huge diversity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023372560bbeb1e10f308276aa5b66d0
https://hal.science/hal-04074453/document

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Light-inducible T cell engagers trigger, tune and shape the activation of primary T cells

Autor: Morgane Jaeger, Amandine Anastasio, Sophie Brustlein, Renaud Vincentelli, Fabien Durbesson, Rémy Char, Maud Boussand, Mathias Lechelon, Rafael J. Argüello, Didier Marguet, Hai-Tao He, Rémi Lasserre

To mount appropriate responses, T cells integrate complex sequences of receptor stimuli perceived during transient interactions with antigen presenting cells. Although it has been hypothesized that the dynamics of these interactions influence the out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58091222095d3444add4d829f82a60ee
https://doi.org/10.1101/2022.04.15.488452

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Endonuclease-based genotyping of the RBM as a method to track the emergence or evolution of SARS-CoV-2 variants

Autor: Xavier de Lamballerie, Alessandra Falchi, Bruno Coutard, Margot Barthelemy, Rémi N. Charrel, Shirley Masse, Cécile Baronti, Renaud Vincentelli, Fabien Durbesson, Eva Lopez

Publikováno v: iScience
iScience, 2021, 24 (11), pp.103329. ⟨10.1016/j.isci.2021.103329⟩
iScience, Vol 24, Iss 11, Pp 103329-(2021)

Since the beginning of the Covid-19 pandemics, variants have emerged. Some of them display increased transmissibility and/or resistance to immune response. Most of the mutations involved in the functional adaptation are found in the Receptor Binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350b6a0920f882fbcb14948cefad9562
https://hal.science/hal-03524036

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Endonuclease-based genotyping of the RBM, a first-line method for the surveillance of emergence or evolution of SARS-CoV-2 Variants

Autor: Rémi N. Charrel, Renaud Vincentelli, Shirley Masse, Fabien Durbesson, Bruno Coutard, Xavier de Lamballerie, Alessandra Falchi, Margot Barthelemy, Eva Lopez, Cécile Baronti

Since the beginning of the Covid-19 pandemics, variants have emerged. Whereas most of them have no to limited selective advantage, some display increased transmissibility and/or resistance to immune response. To date, most of the mutations involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dc82be5426a7f6c0b6b902c01bb8d64
https://doi.org/10.1101/2021.06.16.21259035

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Host PDZ‐containing proteins targeted by SARS‐CoV‐2

Autor: Fabien Durbesson, Nicolas Wolff, Gergo Gogl, Quang Dinh Tran, Célia Caillet-Saguy, Marco Vignuzzi, Veronica V. Rezelj, Renaud Vincentelli, Jean-Claude Twizere

Publikováno v: FEBS Journal
FEBS Journal, Wiley, 2021, ⟨10.1111/febs.15881⟩
FEBS Journal, 2021, ⟨10.1111/febs.15881⟩
The Febs Journal

Small linear motifs targeting protein interacting domains called PSD‐95/Dlg/ZO‐1 (PDZ) have been identified at the C terminus of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) proteins E, 3a, and N. Using a high‐throughput

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3669d4ace2c7195c3ecc7bd6afeb2d9
https://hal-pasteur.archives-ouvertes.fr/pasteur-03214719

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