Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Fabien Delacôte"'
1
Akademický článek
High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes.
Autor: Fabien Delacôte, Christophe Perez, Valérie Guyot, Marianne Duhamel, Christelle Rochon, Nathalie Ollivier, Rachel Macmaster, George H Silva, Frédéric Pâques, Fayza Daboussi, Philippe Duchateau
Publikováno v: PLoS ONE, Vol 8, Iss 1, p e53217 (2013)
Targeting DNA double-strand breaks is a powerful strategy for gene inactivation applications. Without the use of a repair plasmid, targeted mutagenesis can be achieved through Non-Homologous End joining (NHEJ) pathways. However, many of the DNA break
Externí odkaz: https://doaj.org/article/f3cd0e8d8ff24ecf88c47733d9ec4918
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2
Akademický článek
Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach
Autor: Fabien Delacôte, Christophe Perez, Valérie Guyot, Catherine Mikonio, Pierrick Potrel, Jean-Pierre Cabaniols, Christophe Delenda, Frédéric Pâques, Philippe Duchateau
Publikováno v: Journal of Nucleic Acids, Vol 2011 (2011)
Homologous gene targeting (HGT) is a precise but inefficient process for genome engineering. Several methods for increasing its efficiency have been developed, including the use of rare cutting endonucleases. However, there is still room for improvem
Externí odkaz: https://doaj.org/article/e61488346f9f4760adf94a2ded8d2de9
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4
Importance of the cell cycle phase for the choice of the appropriate DSB repair pathway, for genome stability mintenance: the trans-S double-strand break repair model
Autor: Bernard S. Lopez, Fabien Delacôte
Publikováno v: Cell Cycle. 7:33-38
A DNA double-strand break (DSB) is a highly harmful lesion that can lead to genome rearrangements. Two main pathways compete for DSB repair: homologous recombination (HR) and nonhomologous end-joining (NHEJ). Depending on the cell cycle phase, the ch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d054652c2cfb3b3bb7f83ad45c6fccc2
https://doi.org/10.4161/cc.7.1.5149
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6
Human POMp75 is identified as the pro-oncoprotein TLS/FUS: both POMp75 and POMp100 DNA homologous pairing activities are associated to cell proliferation
Autor: Antoine Durrbach, Bernard S. Lopez, Fabien Delacôte, Alexandre T. Akhmedov, Pascale Bertrand
Publikováno v: Oncogene. 18:4515-4521
We have previously developed an assay to measure DNA homologous pairing activities in crude extracts: The POM blot. In mammalian nuclear extracts, we detected two major DNA homologous pairing activities: POMp100 and POMp75. Here, we present the purif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e173ccee9204b664779fa38cc5db61
https://doi.org/10.1038/sj.onc.1203048
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7
High frequency targeted mutagenesis using engineered endonucleases and DNA-End processing enzymes
Autor: Rachel Macmaster, Marianne Duhamel, Valérie Guyot, Christophe Perez, Fayza Daboussi, Nathalie Ollivier, Christelle Rochon, Fabien Delacôte, George H. Silva, Frédéric Pâques, Philippe Duchateau
Publikováno v: Plos One 1 (8), 8 p.. (2013)
PLoS ONE, Vol 8, Iss 1, p e53217 (2013)
PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (1), 8 p. ⟨10.1371/journal.pone.0053217⟩
Targeting DNA double-strand breaks is a powerful strategy for gene inactivation applications. Without the use of a repair plasmid, targeted mutagenesis can be achieved through Non-Homologous End joining (NHEJ) pathways. However, many of the DNA break
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73d492fda24cfdc62da1b192eb3d203
http://prodinra.inra.fr/record/406634
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9
Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach
Autor: Christophe Perez, Christophe Delenda, Valérie Guyot, Jean-Pierre Cabaniols, Fabien Delacôte, Catherine Mikonio, Pierrick Potrel, Frédéric Pâques, Philippe Duchateau
Publikováno v: Journal of Nucleic Acids, Vol 2011 (2011)
Journal of Nucleic Acids
Homologous gene targeting (HGT) is a precise but inefficient process for genome engineering. Several methods for increasing its efficiency have been developed, including the use of rare cutting endonucleases. However, there is still room for improvem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ba319b4ce4f1d0708f97f2bf7c14ff
https://doaj.org/article/e61488346f9f4760adf94a2ded8d2de9
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10
Inhibition of S-phase progression triggered by UVA-induced ROS does not require a functional DNA damage checkpoint response in mammalian cells
Autor: Fabien Delacôte, Mariaelena Pozzebon, Violetta Smirnova, Thierry Douki, Pierre-Marie Girard, Evelyne Sage
Publikováno v: DNA Repair
DNA Repair, 2008, 7 (9), pp.1500-1516. ⟨10.1016/j.dnarep.2008.05.004⟩
Ultraviolet A (UVA) radiation represents more than 90% of the UV spectrum reaching Earth's surface. Exposure to UV light, especially the UVA part, induces the formation of photoexcited states of cellular photosensitizers with subsequent generation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638ff020002813a3ce3bb89942d59d65
https://pubmed.ncbi.nlm.nih.gov/19000790
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