Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Fabien Darfeuille"'
Autor:
Nicolas Tourasse, Fabien Darfeuille
Publikováno v:
Bio-Protocol, Vol 10, Iss 3 (2020)
RNA molecules adopt defined structural conformations that are essential to exert their function. During the course of evolution, the structure of a given RNA can be maintained via compensatory base-pair changes that occur among covarying nucleotides
Externí odkaz:
https://doaj.org/article/a30187d5cf194698bd4501c1f7b93866
Autor:
Sara Masachis, Nicolas J Tourasse, Claire Lays, Marion Faucher, Sandrine Chabas, Isabelle Iost, Fabien Darfeuille
Publikováno v:
eLife, Vol 8 (2019)
Post-transcriptional regulation plays important roles to fine-tune gene expression in bacteria. In particular, regulation of type I toxin-antitoxin (TA) systems is achieved through sophisticated mechanisms involving toxin mRNA folding. Here, we set u
Externí odkaz:
https://doaj.org/article/21a1983998dc4302a92379603a8202dd
Autor:
Fabien Darfeuille, Nicolas J. Tourasse
Publikováno v:
RNA
Type I toxin–antitoxin (T1TA) systems constitute a large class of genetic modules with antisense RNA (asRNA)-mediated regulation of gene expression. They are widespread in bacteria and consist of an mRNA coding for a toxic protein and a noncoding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac3231d09c8b4de1fb7333bd5f57e9b
https://doi.org/10.1261/rna.078802.121
https://doi.org/10.1261/rna.078802.121
Autor:
Anaïs Le Rhun, Nicolas J Tourasse, Simon Bonabal, Isabelle Iost, Fanny Boissier, Fabien Darfeuille
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac940⟩
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac940⟩
Type I toxin–antitoxin systems (T1TAs) are extremely potent bacterial killing systems difficult to characterize using classical approaches. To assess the killing capability of type I toxins and to identify mutations suppressing the toxin expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927c016af9d3825a83cf41c7938475fa
https://hal.science/hal-03872182/document
https://hal.science/hal-03872182/document
Autor:
Cathy Staedel, Christine Varon, Phu Hung Nguyen, Brune Vialet, Lucie Chambonnier, Benoît Rousseau, Isabelle Soubeyran, Serge Evrard, Franck Couillaud, Fabien Darfeuille
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
MicroRNAs regulate eukaryotic gene expression upon pairing onto target mRNAs. This targeting is influenced by the complementarity between the microRNA “seed” sequence at its 5′ end and the seed-matching sequences in the mRNA. Here, we assess th
Externí odkaz:
https://doaj.org/article/7b14f017e3e94564a27a12c0a42dfdfc
Autor:
Jean-Jacques Toulmé, Paloma H. Giangrande, Günter Mayer, Beatrix Suess, Frédéric Ducongé, Bruce Sullenger, Vittorio de Franciscis, Fabien Darfeuille, Eric Peyrin
Publikováno v:
Pharmaceuticals, Vol 10, Iss 1, p 14 (2017)
The symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances f
Externí odkaz:
https://doaj.org/article/72dcd0f4a83d4416a3067b639cdd6f30
Autor:
Nicolas J. Tourasse, Fabien Darfeuille
Type I toxin-antitoxin (T1TA) systems constitute a large class of genetic modules with antisense RNA (asRNA)-mediated regulation of gene expression. They are widespread in bacteria and consist of an mRNA coding for a toxic protein and a noncoding asR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26f21f02d25228c28f3bfe6792c3fd8
https://doi.org/10.1101/2021.04.14.439843
https://doi.org/10.1101/2021.04.14.439843
Autor:
Jessica Baud, Christine Varon, Sandrine Chabas, Lucie Chambonnier, Fabien Darfeuille, Cathy Staedel
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60315 (2013)
Chronic Helicobacter pylori infection provokes an inflammation of the gastric mucosa, at high risk for ulcer and cancer development. The most virulent strains harbor the cag pathogenicity island (cagPAI) encoding a type 4 secretion system, which allo
Externí odkaz:
https://doaj.org/article/c91f30f6b10f4165a2afd1b6702c0e9a
Autor:
Nicolas J. Tourasse, Fabien Darfeuille
Publikováno v:
Bio Protoc
RNA molecules adopt defined structural conformations that are essential to exert their function. During the course of evolution, the structure of a given RNA can be maintained via compensatory base-pair changes that occur among covarying nucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ede124eca8cf1972563bfc50b0b9f60
https://pubmed.ncbi.nlm.nih.gov/33654736
https://pubmed.ncbi.nlm.nih.gov/33654736
Autor:
Isabelle Iost, Fabien Darfeuille, Marion Faucher, Claire Lays, Nicolas J. Tourasse, Sara Masachis, Sandrine Chabas
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.47549⟩
eLife, Vol 8 (2019)
eLife, 2019, 8, ⟨10.7554/eLife.47549⟩
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.47549⟩
eLife, Vol 8 (2019)
eLife, 2019, 8, ⟨10.7554/eLife.47549⟩
Post-transcriptional regulation plays important roles to finely tune gene expression in bacteria. In particular, regulation of type I toxin-antitoxin (TA) systems is achieved through sophisticated mechanisms involving toxin mRNA folding. Here, we set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc57e38a304a22a87749c87a1617dfe
https://hal.archives-ouvertes.fr/hal-02354446
https://hal.archives-ouvertes.fr/hal-02354446