A Decade of Plague in Mahajanga, Madagascar: Insights into the Global Maritime Spread of Pandemic Plague

Autor: Amy J. Vogler, Fabien Chan, Roxanne Nottingham, Genevieve Andersen, Kevin Drees, Stephen M. Beckstrom-Sternberg, David M. Wagner, Suzanne Chanteau, Paul Keim

Publikováno v: mBio, Vol 4, Iss 1 (2013)

ABSTRACT A cluster of human plague cases occurred in the seaport city of Mahajanga, Madagascar, from 1991 to 1999 following 62 years with no evidence of plague, which offered insights into plague pathogen dynamics in an urban environment. We analyzed

Externí odkaz: https://doaj.org/article/7ca0691c24e3471e8abe3a8b3faed316

8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases

Autor: Damijan Knez, Daniel Diez-Iriepa, Mourad Chioua, Andrea Gottinger, Milica Denic, Fabien Chantegreil, Florian Nachon, Xavier Brazzolotto, Anna Skrzypczak-Wiercioch, Anže Meden, Anja Pišlar, Janko Kos, Simon Žakelj, Jure Stojan, Kinga Sałat, Julia Serrano, Ana Patricia Fernández, Aitana Sánchez-García, Ricardo Martínez-Murillo, Claudia Binda, Francisco López-Muñoz, Stanislav Gobec, José Marco-Contelles

Publikováno v: Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 2152-2175 (2023)

We describe the development of quinolylnitrones (QNs) as multifunctional ligands inhibiting cholinesterases (ChEs: acetylcholinesterase and butyrylcholinesterase–hBChE) and monoamine oxidases (hMAO-A/B) for the therapy of neurodegenerative diseases

Externí odkaz: https://doaj.org/article/7f16c8ed45a64b12942b299889a26612

Current epidemiology of human plague in Madagascar

Autor: Lila Rahalison, Dieudoné Rabeson, B. Rasoamanana, Fabien Chan, Pascal Boisier, Jean Roux, Suzanne Chanteau, Ratsitorahina M

Publikováno v: Microbes and Infection. 2:25-31

From 1996 to 1998, 5,965 patients with suspected plague were identified in 38 districts of Madagascar (40% of the total population are exposed). Using standard bacteriology, 917 of them were confirmed or presumptive (C + P) cases. However, more than

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9828eb33be94d25f7f01dd03adafed69
https://doi.org/10.1016/s1286-4579(00)00289-6

Phylogeography and molecular epidemiology of Yersinia pestis in Madagascar

Autor: Paul Keim, Judy Lee, Suzanne Chanteau, David M. Wagner, Jacques Ravel, Roxanne D. Nera, Stephen M. Beckstrom-Sternberg, Mark Achtman, Fabien Chan, Mark Eppinger, Lila Rahalison, B. Rasoamanana, Philippe Roumagnac, Amy J. Vogler

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2011, 5 (9), pp.e1319. ⟨10.1371/journal.pntd.0001319⟩
PLoS Neglected Tropical Diseases, Vol 5, Iss 9, p e1319 (2011)

Background Plague was introduced to Madagascar in 1898 and continues to be a significant human health problem. It exists mainly in the central highlands, but in the 1990s was reintroduced to the port city of Mahajanga, where it caused extensive human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46929fa1441dd09ba842d8ec5eded2b6